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  1. Content type: Research article

    Cordyceps militaris (C. militaris) is reported to exert various immune-activities. To enhance its activity, we fermented C.militaris with Pediococcus pentosaceus ON89A (GRC-ON89A). In this study, we investigated ...

    Authors: Ha-Kyoung Kwon, Woo-Ri Jo and Hye-Jin Park

    Citation: BMC Complementary and Alternative Medicine 2018 18:75

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  2. Content type: Research article

    Uses of polyherbal formulations have played a major role in traditional medicine. The present study is focused on the formulations used in traditional Thai folkloric medicine as tonics or bracers. Twenty docum...

    Authors: Wipawee Chanthasri, Nuntitporn Puangkeaw, Nongluk Kunworarath, Patcharawalai Jaisamut, Surasak Limsuwan, Katesarin Maneenoon, Piyapong Choochana and Sasitorn Chusri

    Citation: BMC Complementary and Alternative Medicine 2018 18:73

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  3. Content type: Research article

    Cumulated evidence reveals that glial cells in the spinal cord play an important role in the development of chronic neuropathic pain and are also complicated in the analgesic effect of EA intervention. But the...

    Authors: Jun-ying Wang, Yong-hui Gao, Li-na Qiao, Jian-liang Zhang, Cheng-Lin Duan-mu, Ya-xia Yan, Shu-ping Chen and Jun-ling Liu

    Citation: BMC Complementary and Alternative Medicine 2018 18:74

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  4. Content type: Research article

    Pancreatic cancer is one of the leading causes of cancer related death and its incidence has risen steadily. Although anticancer drugs have been developed based on the new molecular findings, the drugs have pr...

    Authors: Maiyon Park, Danielle Upton, Melodie Blackmon, Valerie Dixon, Scott Craver, Dawn Neal and Derek Perkins

    Citation: BMC Complementary and Alternative Medicine 2018 18:71

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  5. Content type: Research article

    Evidence suggests that fasting, during which only water is consumed, results in potentially health promoting physiological effects. However, peer-reviewed research assessing the safety of water-only fasting is...

    Authors: John S. Finnell, Bradley C. Saul, Alan C. Goldhamer and Toshia R. Myers

    Citation: BMC Complementary and Alternative Medicine 2018 18:67

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  6. Content type: Research article

    Spinacia oleracea is an important dietary vegetable in India and throughout the world and has many beneficial effects. It is cultivated globally. However, its effect on osteoarthritis that mainly targets the cart...

    Authors: Dharmendra Choudhary, Priyanka Kothari, Ashish Kumar Tripathi, Sonu Singh, Sulekha Adhikary, Naseer Ahmad, Sudhir Kumar, Kapil Dev, Vijay Kumar Mishra, Shubha Shukla, Rakesh Maurya, Prabhat R. Mishra and Ritu Trivedi

    Citation: BMC Complementary and Alternative Medicine 2018 18:69

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  7. Content type: Research article

    Zanthoxylum armatum DC is an important medicinal plant of south East Asia, and has been used to treat various ailments in traditional medicine including diabetes. This study investigated the in vitro and in vivo ...

    Authors: Fiaz Alam, Qazi Najam us Saqib and Mohammad Ashraf

    Citation: BMC Complementary and Alternative Medicine 2018 18:68

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  8. Content type: Research article

    Bauhinia kockiana originates from Peninsular Malaysia and it is grown as a garden ornamental plant. Our previous study reported that this plant exhibited fairly strong antioxidant and antimicrobial activities. Th...

    Authors: Yik Ling Chew, Adlina Maisarah Mahadi, Kak Ming Wong and Joo Kheng Goh

    Citation: BMC Complementary and Alternative Medicine 2018 18:70

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  9. Content type: Research article

    Depression is a common mental disorder. Chai Hu Shu Gan San, a traditional Chinese medicine, is used to treat depression empirically. We present a systematic review and meta-analysis of the therapeutic efficac...

    Authors: Yan Sun, Xia Xu, Jinping Zhang and Yuanyuan Chen

    Citation: BMC Complementary and Alternative Medicine 2018 18:66

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  10. Content type: Research article

    In 2010, the World Health Organization published benchmarks for training in osteopathy in which osteopathic visceral techniques are included. The purpose of this study was to identify and critically appraise t...

    Authors: Albin Guillaud, Nelly Darbois, Richard Monvoisin and Nicolas Pinsault

    Citation: BMC Complementary and Alternative Medicine 2018 18:65

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  11. Content type: Correction

    After the publication [1] it came to the attention of the authors that one of the co-authors was incorrectly included as Hamza Somrain. The correct spelling is as follows: Hamzeh Sumrein.

    Authors: Malek Zihlif, Fatma Afifi, Rana Abu-Dahab, Amin Malik Shah Abdul Majid, Hamza Somrain, Mohanad M. Saleh, Zeyad D. Nassar and Randa Naffa

    Citation: BMC Complementary and Alternative Medicine 2018 18:64

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    The original article was published in BMC Complementary and Alternative Medicine 2013 13:358

  12. Content type: Research article

    Traditional healing practice is an important and integral part of healthcare systems in almost all countries of the world. Very few studies have addressed the holistic scenario of traditional healing practices...

    Authors: Md. Imdadul Haque, A. B. M. Alauddin Chowdhury, Md. Shahjahan and Md. Golam Dostogir Harun

    Citation: BMC Complementary and Alternative Medicine 2018 18:62

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  13. Content type: Research article

    The thyroid gland is one of the largest endocrine glands in the body. The vast majority of TCs (> 90%) originate from follicular cells and are defined as differentiated thyroid cancers (DTC) and the two histol...

    Authors: Angelica Perna, Antonio De Luca, Laura Adelfi, Tammaro Pasquale, Bruno Varriale and Teresa Esposito

    Citation: BMC Complementary and Alternative Medicine 2018 18:63

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  14. Content type: Research article

    Dental caries is considered a multifactorial disease, in which microorganisms play an important role. The diet is decisive in the biofilm formation because it provides the necessary resources for cellular grow...

    Authors: Guilherme Roncari Rocha, Elkin Jahir Florez Salamanca, Ana Letícia de Barros, Carmélia Isabel Vitorino Lobo and Marlise Inêz Klein

    Citation: BMC Complementary and Alternative Medicine 2018 18:61

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  15. Content type: Research article

    Plants used for traditional medicine produce diverse and complex secondary metabolites exhibiting various medicinal properties. The medicinal plant Haplophyllum tuberculatum is used by native people against malar...

    Authors: Assia Hamdi, Joanne Bero, Claire Beaufay, Guido Flamini, Zohra Marzouk, Yvan Vander Heyden and Joelle Quetin-Leclercq

    Citation: BMC Complementary and Alternative Medicine 2018 18:60

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  16. Content type: Research article

    Parkinson’s disease (PD) is a progressive neurodegenerative disorder of the central nervous system. Although the causes of PD pathogenesis remain incomplete, some evidences has suggested that oxidative stress ...

    Authors: Joana Silva, Celso Alves, Susete Pinteus, Susana Mendes and Rui Pedrosa

    Citation: BMC Complementary and Alternative Medicine 2018 18:58

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  17. Content type: Research article

    Gigantol is a bibenzyl compound derived from several medicinal orchids. This biologically active compound has been shown to have promising therapeutic potential against cancer cells, but its mechanism of actio...

    Authors: Shubin Yu, Zhongyuan Wang, Zijie Su, Jiaxing Song, Liang Zhou, Qi Sun, Shanshan Liu, Shiyue Li, Ying Li, Meina Wang, Guo-Qiang Zhang, Xue Zhang, Zhong-Jian Liu and Desheng Lu

    Citation: BMC Complementary and Alternative Medicine 2018 18:59

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  18. Content type: Research article

    Breast cancer remains a leading cause of death in women worldwide. Although breast cancer therapies have greatly advanced in recent years, many patients still develop tumour recurrence and metastasis, and even...

    Authors: Siyamak Ebrahimi Nigjeh, Swee Keong Yeap, Norshariza Nordin, Behnam Kamalideghan, Huynh Ky and Rozita Rosli

    Citation: BMC Complementary and Alternative Medicine 2018 18:56

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  19. Content type: Research article

    Ocimum micranthum Willd is a plant used in traditional medicine practiced in the region of the Yucatan peninsula. In particular, it is used for the treatment of cutaneous infections and wound healing, however the...

    Authors: Isabel O. Caamal-Herrera, Leydi M. Carrillo-Cocom, Diana Y. Escalante-Réndiz, Diana Aráiz-Hernández and José A. Azamar-Barrios

    Citation: BMC Complementary and Alternative Medicine 2018 18:55

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  20. Content type: Research article

    Degradation of components of the extracellular matrix such as elastin and collagen by elastase and collagenase accelerates skin aging. Phytochemicals that inhibit the activity of these enzymes can be developed...

    Authors: Tinotenda Shoko, Vinesh J. Maharaj, Dashnie Naidoo, Malefa Tselanyane, Rudzani Nthambeleni, Eric Khorombi and Zeno Apostolides

    Citation: BMC Complementary and Alternative Medicine 2018 18:54

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  21. Content type: Research article

    Breastfeeding is recommended worldwide but not fully practiced. The first week after childbirth is regarded as a critical period for increasing breast milk production. The aim of the study was to investigate w...

    Authors: Shuaishuai Wang, Chi Zhang, Cuishan Li, Daocheng Li, Ping He, Zhaojuan Su, Yanling Li, Yiling Ding and Aiping Lu

    Citation: BMC Complementary and Alternative Medicine 2018 18:53

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  22. Content type: Research article

    Dracaena cinnabari (DC) is a perennial tree that located on the Southern coast of Yemen native to the Socotra Island. This tree produces a deep red resin known as the Dragon’s blood, the Twobrother’s Blood or Dam...

    Authors: Nashwan Abdullah Al-Afifi, Aied Mohammed Alabsi, Marina Mohd Bakri and Anand Ramanathan

    Citation: BMC Complementary and Alternative Medicine 2018 18:50

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  23. Content type: Research article

    In China, Panax notoginseng has been used to treat oxidative stress-related diseases for a long time. Panax notoginseng saponins is an extract from Panax notoginseng Ledeb. Its therapeutic potential is related to...

    Authors: Ming-wei Liu, Rui Wei, Mei-xian Su, Hui Li, Tian-wen Fang and Wei Zhang

    Citation: BMC Complementary and Alternative Medicine 2018 18:51

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  24. Content type: Research article

    This study was to evaluate the effects of herbal compound 861 (Cpd861) on ski-related novel protein N (SnoN) and transforming growth factor-β1 (TGF-β1) /Smad signaling in rats with bile duct ligation (BDL)-ind...

    Authors: Cheng Chi, Xiao-ya Liu, Fei Hou, Xiao-zheng Yu, Chun-yun Li, Li-jian Cui, Rui-xia Liu and Cheng-hong Yin

    Citation: BMC Complementary and Alternative Medicine 2018 18:52

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  25. Content type: Research article

    Betulinic acid (BA) is a natural triterpenoid compound and exhibits a wide range of biological and medicinal properties including anti-inflammatory activity. Therefore, this theoretical investigation is perfor...

    Authors: Mohammad Firoz Khan, Nusrat Nahar, Ridwan Bin Rashid, Akhtaruzzaman Chowdhury and Mohammad A. Rashid

    Citation: BMC Complementary and Alternative Medicine 2018 18:48

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  26. Content type: Research article

    Cisplatin (CP) drug is platinum compounds used for the treatment of various human malignancies. However, adverse outcomes related to CP restrict its usage. Acacia hydaspica is a natural shrub with various pharmac...

    Authors: Tayyaba Afsar, Suhail Razak, Ali Almajwal and Muhammad Rashid Khan

    Citation: BMC Complementary and Alternative Medicine 2018 18:49

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  27. Content type: Research article

    So-ochim-tang-gamibang (SOCG) is a traditional Korean medicine frequently used for depression in the clinical field. In this study, we evaluated the potential genotoxicity of SOCG using three standard batterie...

    Authors: Mi Young Lee, Yang-Chun Park, Mirim Jin, Eunseok Kim, Jeong June Choi and In Chul Jung

    Citation: BMC Complementary and Alternative Medicine 2018 18:47

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  28. Content type: Research article

    Guang-Pheretima, which is originated from Pheretima aspergillum, has been documented in academic Chinese herbal studies for nearly 2000 years for its prominent treating effects of various inflammatory diseases su...

    Authors: Chuanqi Huang, Wei Li, Qiufeng Zhang, Lihong Chen, Weiming Chen, Hongchao Zhang and Yuxin Ni

    Citation: BMC Complementary and Alternative Medicine 2018 18:46

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  29. Content type: Research article

    Most of herbal medicines are used without any standard safety and toxicological trials although common assumption is that these products are nontoxic. However, this assumption is incorrect and dangerous, so to...

    Authors: Wubayehu Kahaliw, Bjorn Hellman and Ephrem Engidawork

    Citation: BMC Complementary and Alternative Medicine 2018 18:45

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  30. Content type: Research article

    Many complementary therapies offer benefits for patients with cancer. Others may be risky for patients due to negative interactions with conventional treatment and adverse effects. Therefore, cancer patients n...

    Authors: Trine Stub, Sara A. Quandt, Thomas A. Arcury, Joanne C. Sandberg and Agnete E. Kristoffersen

    Citation: BMC Complementary and Alternative Medicine 2018 18:44

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  31. Content type: Research article

    Storage lower urinary tract symptoms (LUTS) including overactive bladder (OAB) and urinary incontinence (UI) affect millions of people worldwide, significantly impacting quality of life. Plant based medicines ...

    Authors: Niikee Schoendorfer, Nita Sharp, Tracey Seipel, Alexander G. Schauss and Kiran D. K. Ahuja

    Citation: BMC Complementary and Alternative Medicine 2018 18:42

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  32. Content type: Research article

    On account of deterioration of chronic heart failure (CHF) and extensive exploration of Chinese herbal injections (CHIs), we performed a network meta-analysis to investigate the efficacy of CHIs (Huangqi injec...

    Authors: Kai-Huan Wang, Jia-Rui Wu, Dan Zhang, Xiao-Jiao Duan and Meng-Wei Ni

    Citation: BMC Complementary and Alternative Medicine 2018 18:41

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  33. Content type: Research article

    Parrotiopsis jacquemontiana (Decne) Rehder. is locally used for skin infections and in wound healing. In this study we have evaluated methanol extract of its leaves and derived fractions against the clinical mult...

    Authors: Saima Ali, Muhammad Rashid Khan, Irfanullah, Moniba Sajid and Zartash Zahra

    Citation: BMC Complementary and Alternative Medicine 2018 18:43

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  34. Content type: Research article

    Cold hypersensitivity in the hands and feet (CHHF) is a common symptom in Korea and patients with CHHF complain of coldness in the hands and feet in an environment that is not considered cold by unaffected peo...

    Authors: Kwang-Ho Bae, Ho-Yeon Go, Ki-Hyun Park, Ilkoo Ahn, Youngheum Yoon and Siwoo Lee

    Citation: BMC Complementary and Alternative Medicine 2018 18:40

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  35. Content type: Research article

    Our team has identified 17 Boreal forest species from the traditional pharmacopeia of the Eastern James Bay Cree that presented promising in vitro and in vivo biological activities in the context of type 2 dia...

    Authors: Shilin Li, Sarah Pasquin, Hoda M. Eid, Jean-François Gauchat, Ammar Saleem and Pierre S. Haddad

    Citation: BMC Complementary and Alternative Medicine 2018 18:37

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  36. Content type: Research article

    Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. The use of natural products has been and continues to be one of the most effective...

    Authors: Victor Kuete, Dominique Ngnintedo, Ghislain W. Fotso, Oğuzhan Karaosmanoğlu, Bonaventure T. Ngadjui, Felix Keumedjio, Samuel O. Yeboah, Kerstin Andrae-Marobela and Hülya Sivas

    Citation: BMC Complementary and Alternative Medicine 2018 18:36

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  37. Content type: Research article

    It has been observed that the various part of Baccaurea ramiflora plant is used in rheumatoid arthritis, cellulitis, abscesses, constipation and injuries. This plant also has anticholinergic, hypolipidemic, hypog...

    Authors: Mst. Luthfun Nesa, S. M. Sajedul Karim, Khairunasa Api, Md. Moklesur Rahman Sarker, Md. Monirul Islam, Asma Kabir, Mithun Kumar Sarker, Kamrun Nahar, Mohammad Asadujjaman and Mohammad Sirajum Munir

    Citation: BMC Complementary and Alternative Medicine 2018 18:35

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  38. Content type: Research article

    Hesperidin is a flavonoid with antioxidant, anti-inflammatory, and immune modulatory activities. Photoaging is a consequence of chronic exposure to the sun and ultraviolet (UV) radiation. This study was design...

    Authors: Hee Jeong Lee, A-Rang Im, Su-Man Kim, Hyung-Sik Kang, Jae Dong Lee and Sungwook Chae

    Citation: BMC Complementary and Alternative Medicine 2018 18:39

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  39. Content type: Research article

    Recent studies have found that plant derived microRNA can cross-kingdom regulate the expression of genes in humans and other mammals, thereby resisting diseases. Can exogenous miRNAs cross the blood-prostate b...

    Authors: Xuan Chen, Ren-zhao Wu, Yong-qiang Zhu, Ze-ming Ren, Ye-ling Tong, Feng Yang and Guan-hai Dai

    Citation: BMC Complementary and Alternative Medicine 2018 18:38

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  40. Content type: Research article

    Skin forms an important part of human innate immune system. Wrinkles, thinning and roughening of skin are some of the symptoms that affect the skin as it ages. Reactive oxygen species induced oxidative stress ...

    Authors: Induja Kalyana Sundaram, Deepika Deeptirekha Sarangi, Vignesh Sundararajan, Shinomol George and Sahabudeen Sheik Mohideen

    Citation: BMC Complementary and Alternative Medicine 2018 18:33

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  41. Content type: Research article

    Sheng-ji Hua-yu(SJHY) formula is one of the most useful Traditional Chinese medicine (TCM) in the treatment of the delayed diabetic wound. However, elucidating the related molecular biological mechanism of how...

    Authors: Le Kuai, Jing-ting Zhang, Yu Deng, Shun Xu, Xun-zhe Xu, Min-feng Wu, Dong-jie Guo, Yu Chen, Ren-jie Wu, Xing-qiang Zhao, Hua Nian, Bin Li and Fu-lun Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:32

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  42. Content type: Research article

    Icariin (ICA), a major ingredient of Epimediumbrevicornum, has various pharmacological activities including central nervous system protective functions such as the improvement of learning and memory function in m...

    Authors: Xiaolong Fu, Shujun Li, Shaoyu Zhou, Qin Wu, Feng Jin and Jingshan Shi

    Citation: BMC Complementary and Alternative Medicine 2018 18:34

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  43. Content type: Research article

    Morinda citrifolia L. that was reported with immunomodulating and cytotoxic effects has been traditionally used to treat multiple illnesses including cancer. An anthraquinone derived from fruits of Morinda citrif...

    Authors: Nadiah Abu, Nur Rizi Zamberi, Swee Keong Yeap, Noraini Nordin, Nurul Elyani Mohamad, Muhammad Firdaus Romli, Nurulfazlina Edayah Rasol, Tamilselvan Subramani, Nor Hadiani Ismail and Noorjahan Banu Alitheen

    Citation: BMC Complementary and Alternative Medicine 2018 18:31

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  44. Content type: Research article

    Because twigs of Cinnamomum cassia (TC) have been reported to exert anti-cancer activity, the mechanistic study for TC’s anti-cancer activity is required. Thus, we elucidated the potential molecular mechanism of ...

    Authors: Gwang Hun Park, Hun Min Song, Su Bin Park, Ho-Jun Son, Yurry Um, Hyun-Seok Kim and Jin Boo Jeong

    Citation: BMC Complementary and Alternative Medicine 2018 18:28

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  45. Content type: Research article

    Different parts including the latex of Ficus racemosa L. has been used as a medicine for wound healing in the Ayurveda and in the indigenous system of medicine in Sri Lanka. This plant has been evaluated for its ...

    Authors: Nisansala Swarnamali Bopage, G. M. Kamal Bandara Gunaherath, Kithsiri Hector Jayawardena, Sushila Chandrani Wijeyaratne, Ajita Mahendra Abeysekera and Seneviratne Somaratne

    Citation: BMC Complementary and Alternative Medicine 2018 18:29

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  46. Content type: Research article

    Natural products obtained from plants can be potent sources for developing a variety of pharmaceutical products. Allium species have been widely studied for their anti-cancer effects and presented promising resul...

    Authors: Ovgu Isbilen, Nahit Rizaner and Ender Volkan

    Citation: BMC Complementary and Alternative Medicine 2018 18:30

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  47. Content type: Research article

    Oxidative stress as well as bacterial and fungal infections are common source of diseases while plants are source of medication for curative or protective purposes. Hence, aim of study was to compare the pharm...

    Authors: Iram Fatima, Sobia Kanwal and Tariq Mahmood

    Citation: BMC Complementary and Alternative Medicine 2018 18:27

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  48. Content type: Research article

    Overweight and obesity are considered major health problems that contribute to increase mortality and quality of life. Both conditions have a high prevalence across the world reaching epidemic numbers. Our aim...

    Authors: Andrea Maia-Landim, Juan M. Ramírez, Carolina Lancho, María S. Poblador and José L. Lancho

    Citation: BMC Complementary and Alternative Medicine 2018 18:26

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