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  1. Study protocol

    Effectiveness of acupuncture for breast cancer related lymphedema: protocol for a single-blind, sham-controlled, randomized, multicenter trial

    Although various treatments for breast cancer related lymphedema exist, there is still a need for a more effective and convenient approach. Pilot studies and our clinical observations suggested that acupunctur...

    Huiru Zhu, Jinwan Li, Zheng Peng, Yujie Huang, Xiaolan Lv, Liuying Song, Gechen Zhou, Shengzhang Lin, Jifei Chen, Baoyu He, Fengxian Qin, Xumexiang Liu, Meiyu Dai, Yan Zou and Shengming Dai

    BMC Complementary and Alternative Medicine 2017 17:467

    Published on: 21 September 2017

  2. Research article

    Post-market outcome of an extract of traditional Cretan herbs on upper respiratory tract infections: a pragmatic, prospective observational study

    The beneficial effects of traditional herbs of Crete, Greece for the treatment of upper respiratory tract infections have been reported in observational and laboratory studies. Following a published, double bl...

    Marilena Anastasaki, Antonios Bertsias, Stergios A. Pirintsos, Elias Castanas and Christos Lionis

    BMC Complementary and Alternative Medicine 2017 17:466

    Published on: 21 September 2017

  3. Research article

    A pilot single centre, double blind, placebo controlled, randomized, parallel study of Calmagen® dermaceutical cream and lotion for the topical treatment of tinea and onychomycosis

    Most of the current anti-fungal treatments are chemical-based, fungistatic, have low efficacy in the treatment of tinea and toxicity concerns, while onychomycosis remains recalcitrant to most antifungal therap...

    Manoj Parekh, Girisha Ramaiah, Prachi Pashilkar, Ranjani Ramanujam, Peter Johnston and Leodevico L. Ilag

    BMC Complementary and Alternative Medicine 2017 17:464

    Published on: 18 September 2017

  4. Research article

    Changes in trust and the use of Korean medicine in South Korea: a comparison of surveys in 2011 and 2014

    Korean medicine (KM) has been widely used in Korea. This study aimed to assess the general perceptions of KM, to investigate the patterns of its usage in 2014, and to compare the results with those of an earli...

    Soohyun Kwon, Shinhee Heo, Dongjun Kim, Seunghyun Kang and Jong-Min Woo

    BMC Complementary and Alternative Medicine 2017 17:463

    Published on: 16 September 2017

  5. Research article

    Plectranthus amboinicus essential oil and carvacrol bioactive against planktonic and biofilm of oxacillin- and vancomycin-resistant Staphylococcus aureus

    The emergence of multidrug-resistant bacteria is a worldwide concern and in order to find an alternative to this problem, the occurrence of antimicrobial compounds in Plectranthus amboinicus essential oil was inv...

    Sara Edwirgens Costa Benício Vasconcelos, Hider Machado Melo, Theodora Thays Arruda Cavalcante, Francisco Eduardo Aragão Catunda Júnior, Mário Geraldo de Carvalho, Francisca Gleire Rodrigues Menezes, Oscarina Viana de Sousa and Renata Albuquerque Costa

    BMC Complementary and Alternative Medicine 2017 17:462

    Published on: 16 September 2017

  6. Research article

    Phytochemical-rich foods inhibit the growth of pathogenic trichomonads

    Plants produce secondary metabolites that often possess widespread bioactivity, and are then known as phytochemicals. We previously determined that several phytochemical-rich food-derived preparations were act...

    Sabrina M. Noritake, Jenny Liu, Sierra Kanetake, Carol E. Levin, Christina Tam, Luisa W. Cheng, Kirkwood M. Land and Mendel Friedman

    BMC Complementary and Alternative Medicine 2017 17:461

    Published on: 13 September 2017

  7. Research article

    Modulation of hippocampal neuronal activity by So-ochim-tang-gamibang in mice subjected to chronic restraint stress

    So-ochim-tang-gamibang (SOCG) is a decoction formula which has been used to improve mental activity in traditional Korean medicine. The present study was performed to evaluate whether ...

    Hwa Chul Shin, Jae Ho Lee, Ki Joong Kim, Hyun Jin Shin, Jeong June Choi, Chan Yong Lee, Uk Namgung and In Chul Jung

    BMC Complementary and Alternative Medicine 2017 17:456

    Published on: 9 September 2017

  8. Research article

    Radix Puerariae and Fructus Crataegi mixture inhibits renal injury in type 2 diabetes via decreasing of AKT/PI3K

    Radix puerariae (RP) is a herbal medicines for diabetes, mainly because of anti-oxidative, insulin resistance and hypoglycemic effect. Fructus crataegi (FC) also possesses strong antioxidant activity in vitro....

    Zhengyue Chen, Yanyan Yuan, Xinrong Zou, Mengqi Hong, Ming Zhao, Yu Zhao, Yuanping Liu, Guofu Li, Yabin Zhu, Lin Luo, Beiyan Bao and Shizhong Bu

    BMC Complementary and Alternative Medicine 2017 17:454

    Published on: 8 September 2017

  9. Research article

    Is cytotoxicity a determinant of the different in vitro and in vivo effects of bioactives?

    Foodstuffs of both plant and animal origin contain a wide range of bioactive compounds. Although human intervention studies are mandatory to assess the health effects of bioactives, the in vitro approach is of...

    Mattia Di Nunzio, Veronica Valli, Lidia Tomás-Cobos, Teresa Tomás-Chisbert, Lucía Murgui-Bosch, Francesca Danesi and Alessandra Bordoni

    BMC Complementary and Alternative Medicine 2017 17:453

    Published on: 7 September 2017

  10. Research article

    Oral administration of taheebo (Tabebuia avellanedae Lorentz ex Griseb.) water extract prevents DSS-induced colitis in mice by up-regulating type II T helper immune responses

    Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders that are mediated by pathogenic Th1 and Th17 cells. Previous studies have demonstrated that taheebo water extract (TWE) derived from Tabebuia ...

    Hyun Jung Park, Sung Won Lee, Dong-Joo Kwon, Seong-Il Heo, Se-Ho Park, Sun Young Kim and Seokmann Hong

    BMC Complementary and Alternative Medicine 2017 17:448

    Published on: 6 September 2017

  11. Research article

    Assessing the quality of reports about randomized controlled trials of scalp acupuncture combined with another treatment for stroke

    This study was designed to assess the quality of reporting on randomized controlled trials (RCTs) of scalp acupuncture for the treatment of stroke.

    Young-Nim You, Myung-Rae Cho, Jae-Hong Kim, Ju-Hyung Park, Gwang-Cheon Park, Min-Yeong Song, Jin-Bong Choi and Jae-Young Han

    BMC Complementary and Alternative Medicine 2017 17:452

    Published on: 6 September 2017

  12. Research article

    Gypenosides ameliorate memory deficits in MPTP-lesioned mouse model of Parkinson’s disease treated with L-DOPA

    Previous studies have revealed that gypenosides (GPS) improve the symptoms of anxiety disorders in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned rat model of Parkinson’s disease (PD). The pres...

    Ting Ting Zhao, Kyung Sook Kim, Keon Sung Shin, Hyun Jin Park, Hyun Jeong Kim, Kyung Eun Lee and Myung Koo Lee

    BMC Complementary and Alternative Medicine 2017 17:449

    Published on: 6 September 2017

  13. Research article

    Isolation and characterization of the compounds responsible for the antimutagenic activity of Combretum microphyllum (Combretaceae) leaf extracts

    Mutations play a major role in the pathogenesis and development of several chronic degenerative diseases including cancer. It follows, therefore that antimutagenic compound may inhibit the pathological process...

    Tshepiso Jan Makhafola, Esameldin Elzein Elgorashi, Lyndy Joy McGaw, Maurice Ducret Awouafack, Luc Verschaeve and Jacobus Nicolaas Eloff

    BMC Complementary and Alternative Medicine 2017 17:446

    Published on: 6 September 2017

  14. Research article

    Subchronic toxicity of herbal compound “Jiedu Huayu” granules in rats

    “Jiedu Huayu” (JDHY) granules are traditional Chinese herbal compounds that have been used to treat severe liver injury for many years. The purpose of the current study is to evaluate the safety of JDHY granules.

    Minggang Wang, Hua Qiu, Rongzhen Zhang, Fuli Long and Dewen Mao

    BMC Complementary and Alternative Medicine 2017 17:450

    Published on: 6 September 2017

  15. Research article

    A national survey of Chinese medicine doctors and clinical practice guidelines in China

    Clinical practice guidelines (CPGs) for Chinese medicine (CM) are being developed to assist doctors with appropriate decisions concerning CM care. To date, there has been little investigation on the perspectiv...

    Mengyu Liu, Chi Zhang, Qinglin Zha, Wei Yang, Ya Yuwen, Linda Zhong, Zhaoxiang Bian, Xuejie Han and Aiping Lu

    BMC Complementary and Alternative Medicine 2017 17:451

    Published on: 6 September 2017

  16. Study protocol

    Will Chinese external therapy with compound Tripterygium wilfordii hook F gel safely control disease activity in patients with rheumatoid arthritis: design of a double-blinded randomized controlled trial

    Chinese external therapy (CET) is a topical application with mainly Chinese herb medicine therapy with thousands of years of historical implications and is a clinical routine that is commonly used for relievin...

    Quan Jiang, Xiao-Po Tang, Xian-Chun Chen, Hong Xiao, Ping Liu and Juan Jiao

    BMC Complementary and Alternative Medicine 2017 17:444

    Published on: 5 September 2017

  17. Research article

    Anticancer activity of calyx of Diospyros kaki Thunb. through downregulation of cyclin D1 via inducing proteasomal degradation and transcriptional inhibition in human colorectal cancer cells

    Although it has been reported to contain high polyphenols, the pharmacological studies of the calyx of Diospyros kaki Thunb (DKC) have not been elucidated in detail. In this study, we elucidated anti-cancer activ...

    Su Bin Park, Gwang Hun Park, Hun Min Song, Ho-Jun Son, Yurry Um, Hyun-Seok Kim and Jin Boo Jeong

    BMC Complementary and Alternative Medicine 2017 17:445

    Published on: 5 September 2017

  18. Research article

    Agrimonia pilosa Ledeb. aqueous extract improves impaired glucose tolerance in high-fat diet-fed rats by decreasing the inflammatory response

    Agrimonia pilosa Ledeb. is a medicinal plant with physiological activities such as anti-cancer, antioxidant, anti-inflammatory activities and in vitro anti-diabetic activity. However, ...

    Hwan Hee Jang, Song Yee Nam, Mi Ju Kim, Jung Bong Kim, Jeong Sook Choi, Haeng Ran Kim and Young Min Lee

    BMC Complementary and Alternative Medicine 2017 17:442

    Published on: 5 September 2017

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