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  1. Content type: Research article

    Rapid emergence of multidrug resistant (MDR) organisms in hospital and community settings often result into treatment failure, thus leading the clinicians with fewer treatment options. Cyathea gigantea, an ethnom...

    Authors: Kathakali Nath, Anupam Das Talukdar, Mrinal Kanti Bhattacharya, Deepshikha Bhowmik, Shiela Chetri, Debarati Choudhury, Abhijit Mitra and Nargis Alom Choudhury

    Citation: BMC Complementary and Alternative Medicine 2019 19:279

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  2. Content type: Research article

    Recent epidemiological and experimental studies suggest that cadmium and diabetes-related hyperglycemia may act synergistically to worsen metabolic regulation. The present study aims to evaluate the potential ...

    Authors: Mohammad Nazmul Hasan, Farah Sabrin, Begum Rokeya, Md Shahinul Haque Khan, Mahtab Uddin Ahmed, Abel Matondo, Md Morsaline Billah and Salima Akter

    Citation: BMC Complementary and Alternative Medicine 2019 19:278

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  3. Content type: Research article

    Clinical Practice Guidelines (CPGs) play an important role in clinical practice, and they require appropriate evaluation, especially in application. This study explores the application evaluation method of CPG...

    Authors: Huayang Cai, Hui Li, Huizhen Zeng, Danping Xu, Wenwei Ouyang and Aiping Lv

    Citation: BMC Complementary and Alternative Medicine 2019 19:277

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  4. Content type: Research article

    Lead, mercury, cadmium, chromium, and arsenic intoxication have been associated with the use of health supplement (HS) products. The aim of this study is to estimate the concentration of heavy metals in HS pro...

    Authors: Naseem Mohammed Abdulla, Balazs Adam, Iain Blair and Abderrahim Oulhaj

    Citation: BMC Complementary and Alternative Medicine 2019 19:276

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  5. Content type: Research article

    Pyrola decorata H. Andres, is exclusively distributed in China and a source of traditional Chinese herbal medicine Luxiancao for more than 2000 years. Here, we evaluated the antioxidant and cytoprotective effects...

    Authors: Ban Chen, Xican Li, Jie Liu, Wei Qin, Minshi Liang, Qianru Liu and Dongfeng Chen

    Citation: BMC Complementary and Alternative Medicine 2019 19:275

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  6. Content type: Research article

    Recent research has suggested that autophagy can provide a better mechanism for inducing cell death than current therapeutic strategies. This study investigated the effects of using an ethanol extract of Chrys...

    Authors: Kwang-Youn Kim, Tae-Woo Oh, Hye-Jin Yang, Young-Woo Kim, Jin-Yeul Ma and Kwang-Il Park

    Citation: BMC Complementary and Alternative Medicine 2019 19:274

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  7. Content type: Research article

    Curcumin is known for its multitude of medicinal properties, including anti-cancer and migrastatic activity. Efforts to overcome poor bioavailability, stability, and side effects associated with the higher dos...

    Authors: Jinsha Koroth, Snehal Nirgude, Shweta Tiwari, Vidya Gopalakrishnan, Raghunandan Mahadeva, Sujeet Kumar, Subhas S. Karki and Bibha Choudhary

    Citation: BMC Complementary and Alternative Medicine 2019 19:273

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  8. Content type: Research article

    This study aimed to investigate the effect of the Phellinus linteus (Mesima) decoction on podocyte injury in a rat model of focal and segmental glomerulosclerosis (FSGS) and evaluate the potential mechanisms.

    Authors: Feng Wan, Ru-chun Yang, Yan-peng Shi, Yue-Wen Tang, Xuan-li Tang, Xiao-ling Zhu, You-gui Li and Yong-jun Wang

    Citation: BMC Complementary and Alternative Medicine 2019 19:272

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  9. Content type: Research article

    Plant secondary metabolites and phytochemicals that exhibit strong bioactivities have potential to be developed as safe and efficient natural antimicrobials against food contamination and addressing antimicrob...

    Authors: Dan Zhou, Ze-Hua Liu, Dong-Mei Wang, Deng-Wu Li, Li-Na Yang and Wei Wang

    Citation: BMC Complementary and Alternative Medicine 2019 19:271

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  10. Content type: Research article

    Benign prostatic hyperplasia (BPH) is a pathological condition affecting older men. BPH complications often lead to deterioration in the quality of life. Serenoa repens (Saw Palmetto) is used for treating lower u...

    Authors: Heggar V. Sudeep, Karempudi Venkatakrishna, Ballal Amrutharaj, Anitha and Kodimule Shyamprasad

    Citation: BMC Complementary and Alternative Medicine 2019 19:270

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  11. Content type: Research article

    Puerarin exerts therapeutic effect on osteoporosis due to its inhibitory effect on the formation of osteoclasts. Puerarin is also widely established as an autophagy inhibitor. The study aimed to investigate th...

    Authors: Guoyou Zhang, Yu Wang, Guoke Tang and Yuanzheng Ma

    Citation: BMC Complementary and Alternative Medicine 2019 19:269

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  12. Content type: Research article

    Long-term use of most immunosuppressants to treat allergic contact dermatitis (ACD) generates unavoidable severe side effects, warranting discovery or development of new immunosuppressants with good efficacy a...

    Authors: Premrutai Thitilertdecha, Panwadee Pluangnooch, Sunita Timalsena and Kitipong Soontrapa

    Citation: BMC Complementary and Alternative Medicine 2019 19:268

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  13. Content type: Research article

    Cancer cachexia is a cancer-induced multifactorial debilitating syndrome directly accounting for 20% of cancer deaths without effective therapeutic approaches. It is extremely urgent to explore effective anti-...

    Authors: Huiquan Liu, Lu Li, Jun Zou, Ting Zhou, Bangyan Wang, Huihui Sun and Shiying Yu

    Citation: BMC Complementary and Alternative Medicine 2019 19:267

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  14. Content type: Research article

    Propolis is a natural bee product with a wide range of biological activities that are related to its chemical composition. The present study investigated the quantification of quercetin (Q) in Ardabil ethanol ...

    Authors: Fariba Asgharpour, Ali Akbar Moghadamnia, Ebrahim Zabihi, Sohrab Kazemi, Amirmorteza Ebrahimzadeh Namvar, Hemmat Gholinia, Mina Motallebnejad and Hamid Reza Nouri

    Citation: BMC Complementary and Alternative Medicine 2019 19:266

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  15. Content type: Research article

    Carica papaya (CP) extract is becoming popular as an unlicensed herbal remedy purported to hasten recovery in dengue infection, mostly based on observations that it may increase platelet counts. This systematic r...

    Authors: Senaka Rajapakse, Nipun Lakshitha de Silva, Praveen Weeratunga, Chaturaka Rodrigo, Chathurani Sigera and Sumadhya Deepika Fernando

    Citation: BMC Complementary and Alternative Medicine 2019 19:265

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  16. Content type: Research article

    Osteoarthritis (OA) is a common degenerative disease of synovial joints caused by inflammation. Acteoside (ACT), a major component and lipase inhibitor from the Chinese tea Ligustrum purpurascens kudingcha, has b...

    Authors: Zhiguang Qiao, Jiaxin Tang, Wen Wu, Jian Tang and Ming Liu

    Citation: BMC Complementary and Alternative Medicine 2019 19:264

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  17. Content type: Research article

    Inflammation is a symptom associated with many diseases. This symptom is treated with steroidal and non-steroidal anti-inflammatory drugs, which can cause severe side effects when used as long-term treatments....

    Authors: Axel Villagómez-Rodríguez, Julia Pérez-Ramos, Ana Laura Esquivel-Campos, Cuauhtémoc Pérez-González, Claudia Angélica Soto-Peredo and Salud Pérez-Gutiérrez

    Citation: BMC Complementary and Alternative Medicine 2019 19:263

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  18. Content type: Research article

    Natural products play a significant role in human health in relation to the prevention and treatment of inflammatory conditions. One of the plants with great medicinal potentials is Diospyros kaki which is mainly...

    Authors: Jieun Choi, Mi Jeong Kim, Richard Komakech, Haiyoung Jung and Youngmin Kang

    Citation: BMC Complementary and Alternative Medicine 2019 19:262

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  19. Content type: Research article

    Our previous study exhibited free radicals scavenging and antioxidant activities of ethanolic and aqueous extracts of Tamarindus indica L. leaves in chronic sodium fluoride poisoning in rats. Tamarindus indica L....

    Authors: Bishnu Prasad Sinha, Souvick Chatterjee, Rinku Buragohain, Indranil Samanta, Siddhartha Narayan Joardar, Prasenjit Mukherjee, Asit Kumar Maji, Partha Das, Tapan Kumar Mandal and Tapas Kumar Sar

    Citation: BMC Complementary and Alternative Medicine 2019 19:261

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  20. Content type: Research article

    Dengue is a mosquito-borne viral infection that has become a major public health concern worldwide. Presently, there is no specific vaccine or treatment available for dengue viral infection.

    Authors: Kavithambigai Ellan, Ravindran Thayan, Jegadeesh Raman, Kazuya I. P. J. Hidari, Norizah Ismail and Vikineswary Sabaratnam

    Citation: BMC Complementary and Alternative Medicine 2019 19:260

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  21. Content type: Research article

    Traditional and complementary medicines (T&CM) are any form of medicine, practice, treatment, product, technology, knowledge system or ceremony outside of conventional medical practice that aims to prevent and...

    Authors: A. Gall, K. Anderson, J. Adams, V. Matthews and G. Garvey

    Citation: BMC Complementary and Alternative Medicine 2019 19:259

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  22. Content type: Research article

    Herbal and traditional medicines (HTM) are widely used in Asian countries. Specific data on prevalent of HTM usage and association with chronic diseases in the Thai population is currently lacking. We examined...

    Authors: Napatt Kanjanahattakij, Pakakrong Kwankhao, Prin Vathesatogkit, Nisakron Thongmung, Yingampa Gleebbua, Piyamitr Sritara and Chagriya Kitiyakara

    Citation: BMC Complementary and Alternative Medicine 2019 19:258

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  23. Content type: Research article

    Clinacanthus nutans extracts have been consumed by the cancer patients with the hope that the extracts can kill cancers more effectively than conventional chemotherapies. Our previous study reported its anti-infl...

    Authors: Ling-Wei Hii, Swee-Hua Erin Lim, Chee-Onn Leong, Swee-Yee Chin, Ngai-Paing Tan, Kok-Song Lai and Chun-Wai Mai

    Citation: BMC Complementary and Alternative Medicine 2019 19:257

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  24. Content type: Research article

    Arisaema jacquemontii is traditionally used in treatment of different diseases. In this study, phytochemical, in vitro biological and chemo-preventive screening of A. jacquemontii was carried out to explore its p...

    Authors: Saira Tabassum, Muhammad Zia, Esperanza J. Carcahe de Blanco, Riffat Batool, Roohi Aslam, Sajid Hussain, Qamar Wali and Muhammad Mudassar Gulzar

    Citation: BMC Complementary and Alternative Medicine 2019 19:256

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  25. Content type: Research article

    Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is characterized by excessive hepatic lipid accumulation. Many studies have suggested that lipid overload is the key initi...

    Authors: Ke Fang, Fan Wu, Guang Chen, Hui Dong, Jingbin Li, Yan Zhao, Lijun Xu, Xin Zou and Fuer Lu

    Citation: BMC Complementary and Alternative Medicine 2019 19:255

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  26. Content type: Research article

    Fumaria species (Fumariacea) has traditionally been used in wound healing in Iranian folk medicine. However, with the discovery of newer agents, its use has faded off into total obscurity. This study explored the...

    Authors: Fatemeh Davoodi-Roodbordeii, Minoo Afshar, Fatemeh Haji Abas Tabrizi, Samira Choopani, Giti Torkaman, Fariborz Moayer and Mona Salimi

    Citation: BMC Complementary and Alternative Medicine 2019 19:254

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  27. Content type: Research article

    General antiviral agents such as oseltamivir are associated with certain adverse effects and the emergence of resistance. This study investigated the phytochemical properties, antiviral activities, and safety ...

    Authors: Won-Young Bae, Hyeong-Yeop Kim, Kyoung-Sook Choi, Kyung Hoon Chang, Young-Ho Hong, Jongsu Eun, Na-Kyoung Lee and Hyun-Dong Paik

    Citation: BMC Complementary and Alternative Medicine 2019 19:253

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  28. Content type: Research article

    Turmeric is commonly used as a dietary treatment for inflammation, but few studies have evaluated the direct effect of turmeric on cartilage. The purpose of this study was to characterize cartilage explants’ i...

    Authors: Wendy Pearson and Laima S. Kott

    Citation: BMC Complementary and Alternative Medicine 2019 19:252

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  29. Content type: Research article

    While traditional, complementary and alternative medicine (TCAM) is gaining increased interest worldwide, the structural factors associated with the usage of TCAM at the social level have not been sufficiently...

    Authors: Jimpei Misawa, Rie Ichikawa, Akiko Shibuya, Yukihiro Maeda, Ichiro Arai, Teruyoshi Hishiki and Yoshiaki Kondo

    Citation: BMC Complementary and Alternative Medicine 2019 19:251

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  30. Content type: Research article

    Parents’ use of complementary health approaches (CHA) for children with autism spectrum disorder (ASD) are common despite the uncertain evidence of its benefit. Parents often adopt CHA due to dissatisfaction w...

    Authors: Jun Jean Ong

    Citation: BMC Complementary and Alternative Medicine 2019 19:250

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  31. Content type: Research article

    Bacteria have developed resistance to most of the current antibiotics. There is evidence suggesting that plant-derived compounds have a potential for interacting with biological processes. One of the plants co...

    Authors: Winnie Mozirandi, Dexter Tagwireyi and Stanley Mukanganyama

    Citation: BMC Complementary and Alternative Medicine 2019 19:249

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  32. Content type: Research article

    With the current concern caused by drug resistant microorganisms, alternatives to traditional antimicrobials are increasingly necessary. Historical holistic treatments involving natural approaches are now of i...

    Authors: Rhegan C. McGregor, Kory A. Parker, Jacob M. Hornby and Leigh C. Latta IV

    Citation: BMC Complementary and Alternative Medicine 2019 19:247

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  33. Content type: Research article

    Cosmos caudatus is an annual plant known for its medicinal value in treating several health conditions, such as high blood pressure, arthritis, and diabetes mellitus. The α-glucosidase inhibitory activity and tot...

    Authors: Wan Ahmad Wan-Nadilah, Muhammad Tayyab Akhtar, Khozirah Shaari, Alfi Khatib, Azizah Abdul Hamid and Muhajir Hamid

    Citation: BMC Complementary and Alternative Medicine 2019 19:245

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  34. Content type: Research article

    Catalpol, a natural iridoid glycoside in Rehmannia glutinosa, can alleviate proteinuria associated with diabetic nephropathy (DN), however, whether catalpol has a protective effect against podocyte injury in DN r...

    Authors: Yan Chen, Qingpu Liu, Zengfu Shan, Yingying Zhao, Meng Li, Baiyan Wang, Xiaoke Zheng and Weisheng Feng

    Citation: BMC Complementary and Alternative Medicine 2019 19:244

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  35. Content type: Research article

    Brown adipocytes are known to promote energy expenditure and limit weight gain to combat obesity. Averrhoa bilimbi, locally called belimbing buluh (DBB), is mainly used as an ethnomedicine in the treatment of met...

    Authors: Wai Kwan Lau, Nur Adelina Ahmad Noruddin, Abdul Hadi Ariffin, Muhd Zulkarnain Mahmud, Mohd Hasnan Mohd Noor, Azimah Amanah, Mohamad Faiz Hamzah and Zainuddin Zafarina

    Citation: BMC Complementary and Alternative Medicine 2019 19:243

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  36. Content type: Research article

    Cyanidin-3-rutinoside (C3R), a naturally occurring anthocyanin, possesses anti-oxidant, anti-hyperglycemic, anti-glycation and cardioprotective properties. However, its mechanisms responsible for anti-hyperlip...

    Authors: Thavaree Thilavech and Sirichai Adisakwattana

    Citation: BMC Complementary and Alternative Medicine 2019 19:242

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  37. Content type: Research article

    Mulberry silkworm larvae (Bombyx mori) are known as the oldest resource of food and traditional medicine. Although silkworm larvae have been reported to treat various chronic diseases, the effect of fermentation ...

    Authors: Hyun-Dong Cho, Hye-Ji Min, Yeong-Seon Won, Hee-Young Ahn, Young-Su Cho and Kwon-Il Seo

    Citation: BMC Complementary and Alternative Medicine 2019 19:241

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  38. Content type: Research article

    Major depression is an important complication in patients with breast cancer, but is an underrecognized and undertreated condition in this population. The Baihe Zhimu Tang (BZ formula) is a traditional Chinese...

    Authors: Hailong Li, Chunyu Wu, Yu Liu, Shuo Zhang and Xiufei Gao

    Citation: BMC Complementary and Alternative Medicine 2019 19:240

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  39. Content type: Research article

    Chronic obstructive pulmonary disease (COPD) is one global disease. Lung function gradually declines. Medication does not fully reverse the airflow limitation. Qigong’s role in COPD rehabilitation has been ass...

    Authors: Hongxuan Tong, Yihua Liu, Yutian Zhu, Boli Zhang and Jingqing Hu

    Citation: BMC Complementary and Alternative Medicine 2019 19:239

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  40. Content type: Research article

    Annonacin, an annonaceous acetogenin isolated from Annona muricata has been reported to be strongly cytotoxic against various cell lines, in vitro. Nevertheless, its effect against in vivo tumor promoting activit...

    Authors: Mohd Rohaizad Md Roduan, Roslida Abd Hamid and Norhafizah Mohtarrudin

    Citation: BMC Complementary and Alternative Medicine 2019 19:238

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  41. Content type: Research article

    Rice husk, a waste material produced during milling, contains numerous phytochemicals that may be sources of cancer chemopreventive agents. Various biological activities of white and colored rice husk have bee...

    Authors: Arpamas Chariyakornkul, Charatda Punvittayagul, Sirinya Taya and Rawiwan Wongpoomchai

    Citation: BMC Complementary and Alternative Medicine 2019 19:237

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  42. Content type: Research article

    Syzygium cumini (L.) Skeels. is one of the very popular traditionally used medicinal plants with numerous pharmacological activities including antioxidant, hypoglycemic and anti-inflammatory. However, actions of

    Authors: Ahad Abdul Rehman, Azra Riaz, Muhammad Arif Asghar, Muhammad Liaquat Raza, Shadab Ahmed and Kamran Khan

    Citation: BMC Complementary and Alternative Medicine 2019 19:236

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  43. Content type: Research article

    Oxyresveratrol is a major bioactive component derived from the heartwood of Artocarpus lacucha. This compound exerts several biological activities, including neuroprotective effects in vitro and in vivo. However,...

    Authors: Dhirarin Junsaeng, Tosapol Anukunwithaya, Phanit Songvut, Boonchoo Sritularak, Kittisak Likhitwitayawuid and Phisit Khemawoot

    Citation: BMC Complementary and Alternative Medicine 2019 19:235

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  44. Content type: Research article

    The neurobiology of persistent pain shares common underlying psychobiology with that of traumatic stress. Modern treatments for traumatic stress often involve bottom-up sensorimotor retraining/exposure therapi...

    Authors: Alison Flehr, Christopher Barton, Jan Coles, Stephen J. Gibson, Gavin W. Lambert, Elisabeth A. Lambert, Arup K. Dhar and John B. Dixon

    Citation: BMC Complementary and Alternative Medicine 2019 19:234

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  45. Content type: Research article

    Resveratrol is reported to inhibit the growth of prostate, which is characteristic of benign prostatic hyperplasia (BPH) condition. However, the mechanism remains unclear. This study aimed to identify the effe...

    Authors: Chao Li, Wan-Li Hu, Meng-Xin Lu and Guan-Fa Xiao

    Citation: BMC Complementary and Alternative Medicine 2019 19:233

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  46. Content type: Research article

    Metabolic syndrome is a non-communicable disease inclusive of risk factors such as central obesity, hypertension, hyperglycaemia and dyslipidaemia. In this present study, we investigated the ability of Pandanus a...

    Authors: Nur Hidayah Reshidan, Suhaila Abd Muid and Norshalizah Mamikutty

    Citation: BMC Complementary and Alternative Medicine 2019 19:232

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  47. Content type: Research article

    In Korea and China, asiasari radix (AR) is widely used as a traditional anti-inflammatory and analgesic agent. After its skin-regenerating and hair loss-preventing activities were identified, several types of ...

    Authors: Kwang-Ha Park, Jeong-Hae Choi, Yeon-Suk Song, Gyoo-Cheon Kim and Jin-Woo Hong

    Citation: BMC Complementary and Alternative Medicine 2019 19:231

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  48. Content type: Research article

    Hyperglycemia and dyslipidemia are classic features of patients with diabetes mellitus (DM). Cordyceps taii, a folk medicinal fungus native to southern China, possesses various pharmacological activities. This st...

    Authors: Ru-Ming Liu, Rong Dai, Yi Luo and Jian-Hui Xiao

    Citation: BMC Complementary and Alternative Medicine 2019 19:230

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