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  1. Content type: Research article

    Rubus coreanus fruit (RF) has been used as a traditional medicine formulation to treat various diseases including diarrhea, asthma, and cancer in East Asia (Korea, China, and Japan). RF, which is native to Korea,...

    Authors: Kyung Hye Seo, Ji Yeon Lee, Jeong-Yong Park, Gwi Yeong Jang, Hyung Don Kim, Young- Seob Lee and Dong Hwi Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:89

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  2. Content type: Research article

    Stevia rebaudiana Bertoni has various pharmacological actions, which includes antidiabetic, antioxidant, anti-inflammatory activities. The superoxide and consequently NADPH oxidase (Nox) are relevant targets invo...

    Authors: A. S. Isoyan, K. V. Simonyan, R. M. Simonyan, M. A. Babayan, G. M. Simonyan, V. A. Chavushyan and M. A. Simonyan

    Citation: BMC Complementary and Alternative Medicine 2019 19:88

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  3. Content type: Research article

    Whole-body electrical myostimulation (WB-EMS) is a relatively recent training methodology that has been extraordinarily used in recent years. However, there is a lack of consensus on the effectiveness of WB-EM...

    Authors: Alvaro Pano-Rodriguez, Jose Vicente Beltran-Garrido, Vicenç Hernández-González and Joaquim Reverter-Masia

    Citation: BMC Complementary and Alternative Medicine 2019 19:87

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  4. Content type: Research article

    The modified Si-Jun-Zi Decoction (SJZ), a Chinese medicine formula, is clinically used against multiple malignancies including colorectal cancer (CRC). This study aims to evaluate the effect of modified SJZ on...

    Authors: Jin-Yong Zhou, Min Chen, Cun-En Wu, Yu-Wen Zhuang, Yu-Gen Chen and Shen-Lin Liu

    Citation: BMC Complementary and Alternative Medicine 2019 19:86

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  5. Content type: Research article

    In 2011 there was a strengthening of European Union (EU) legislation on the licencing of herbal products which, in the UK, resulted in the introduction of the Traditional Herbal Registration (THR) scheme. This...

    Authors: R. Dickinson, M. C. Kennedy, D. K. Raynor, P. Knapp, M. Thomas and E. Adami

    Citation: BMC Complementary and Alternative Medicine 2019 19:85

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  6. Content type: Case report

    Fructus Psoraleae is the seed of Psoralea corylifolia Linn. Fructus Psoraleae has been shown to be effective in treating some skin diseases, such as vitiligo. As a main ingredient in five types of herbs in the Qu...

    Authors: Ang Li, Minhong Gao, Na Zhao, Ping Li, Jinguo Zhu and Wenfei Li

    Citation: BMC Complementary and Alternative Medicine 2019 19:84

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  7. Content type: Research article

    Integrative and complementary health approaches (ICHA) are often pursued by patients facing chronic illnesses. Most of the studies that investigated the factors associated with ICHA consumption have considered...

    Authors: Fabrice Berna, Anja S. Göritz, Amaury Mengin, Renaud Evrard, Jacques Kopferschmitt and Steffen Moritz

    Citation: BMC Complementary and Alternative Medicine 2019 19:83

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  8. Content type: Research article

    Cytinus is small genus of endophytic parasitic plants distributed in South Africa, Madagascar, and in the Mediterranean region. In the latter area, two species occur, Cytinus hypocistis and C. ruber, distinguishe...

    Authors: Giuseppantonio Maisetta, Giovanna Batoni, Pierluigi Caboni, Semih Esin, Andrea C. Rinaldi and Paolo Zucca

    Citation: BMC Complementary and Alternative Medicine 2019 19:82

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  9. Content type: Research article

    Diabetic nephropathy (DN) is a common complication of diabetes mellitus (DM) that imposes an enormous burden on the healthcare system. Although some studies show that traditional Chinese medicine (TCM) treatme...

    Authors: Hsing-Yu Chen, Heng-Chih Pan, Yung-Chang Chen, Yu-Chun Chen, Yi-Hsuan Lin, Sien-Hung Yang, Jiun-Liang Chen and Hau-Tieng Wu

    Citation: BMC Complementary and Alternative Medicine 2019 19:81

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  10. Content type: Research article

    Organochalcogen compounds have attracted the interest of a multitude of studies for their promising Pharmacological and biological activities. The antioxidant activity and acute toxicity of an organoselenium c...

    Authors: Mohammad Ibrahim, Niaz Muhammad, Musadiq Ibrahim, Muhammad Idrees Khan, Muhammad Ishaq Ali Shah, Muhammad Said, Waliullah Khan, Jean Paul Kamdem and Joao Batista Teixeira Rocha

    Citation: BMC Complementary and Alternative Medicine 2019 19:80

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  11. Content type: Research article

    Methanol extract (MECN) of Clinacanthus nutans Lindau leaves (family Acanthaceae) demonstrated peripherally and centrally mediated antinociceptive activity via the modulation of opioid/NO-mediated, but cGMP-indep...

    Authors: Zainul Amiruddin Zakaria, Mohammad Hafiz Abdul Rahim, Mohd Hijaz Mohd Sani, Maizatul Hasyima Omar, Siew Mooi Ching, Arifah Abdul Kadir and Qamar Uddin Ahmed

    Citation: BMC Complementary and Alternative Medicine 2019 19:79

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  12. Content type: Research article

    Teaching Complementary and alternative medicine (CAM) in medical schools is becoming prevalent worldwide. Few studies have been conducted to evaluate medical students’ knowledge and attitude toward CAM. Theref...

    Authors: Ahmad M. Samara, Ethar R. Barabra, Hala N. Quzaih and Sa’ed H. Zyoud

    Citation: BMC Complementary and Alternative Medicine 2019 19:78

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  13. Content type: Research article

    Cordyceps is a traditional Chinese herb that produces various biopharmaceutical effects, including immune-enhancing effects. In this study, we prepared a Cordyceps mycelium culture extract (Paecilomyces hepiali, ...

    Authors: Su-Jin Jung, Eun-Soo Jung, Eun-Kyung Choi, Hong-Sig Sin, Ki-Chan Ha and Soo-Wan Chae

    Citation: BMC Complementary and Alternative Medicine 2019 19:77

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  14. Content type: Research article

    Music has been shown to improve health and quality of life. It was suggested that music may also have an impact on gait stability and fall risk. Yet, few studies have exploited music in the hospital setting, a...

    Authors: Julia Chabot, Olivier Beauchet, Shek Fung and Isabelle Peretz

    Citation: BMC Complementary and Alternative Medicine 2019 19:76

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  15. Content type: Research article

    The introduction of imatinib revolutionized the treatment of chronic myeloid leukaemia (CML), substantially extending patient survival. However, imatinib resistance is currently a clinical problem for CML. It ...

    Authors: Huayao Li, Lijuan Liu, Jing Zhuang, Cun Liu, Chao Zhou, Jing Yang, Chundi Gao, Gongxi Liu and Changgang Sun

    Citation: BMC Complementary and Alternative Medicine 2019 19:75

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  16. Content type: Research article

    Different plant parts of Roylea cinerea (D. Don) Baill. (Lamiaceae), Clematis grata Wall. (Ranunculaceae), Cornus capitata Wall. (Cornaceae) are traditionally used in the management of diabetes and various other ...

    Authors: Astha Bhatia, Balbir Singh, Rohit Arora and Saroj Arora

    Citation: BMC Complementary and Alternative Medicine 2019 19:74

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  17. Content type: Research article

    Complementary Medicine (CM) continues to thrive across many countries. Closely related to the continuing popularity of CM has been an increased number of enrolments at CM education institutions across the publ...

    Authors: Alastair C. Gray, Amie Steel and Jon Adams

    Citation: BMC Complementary and Alternative Medicine 2019 19:73

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  18. Content type: Research article

    Solidago chilensis (syn. microglossa) is a plant from the Asteraceae family widely distributed in South America and used to treat inflammatory diseases. In 2009, it was listed as one of the native medicinal herba...

    Authors: Elena L. A. Malpezzi-Marinho, Graziela R. Molska, Lyvia I. G. P. Freire, Cristiane I. Silva, Eduardo K. Tamura, Laís F. Berro, Carlos A. Parada and Eduardo Ary Villela Marinho

    Citation: BMC Complementary and Alternative Medicine 2019 19:72

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  19. Content type: Research article

    Ocimum gratissimum L. is a medicinal plant widely grown in tropical and subtropical regions with the leaf decoction usually taken in folk medicine to enhance erectile performance in men although the probable mech...

    Authors: Oluwafemi Adeleke Ojo, Adebola Busola Ojo, Babatunji Emmanuel Oyinloye, Basiru Olaitan Ajiboye, Omosola Olufisayo Anifowose, Ayodeji Akawa, Oluranti Esther Olaiya, Oluwaseun Ruth Olasehinde and Abidemi Paul Kappo

    Citation: BMC Complementary and Alternative Medicine 2019 19:71

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  20. Content type: Research article

    Influenza is a common viral infection worldwide. Maoto (ma-huang-tang) was developed in ancient China and is used to alleviate flu symptoms. Currently, no meta-analyses have evaluated the efficacy and safety of m...

    Authors: Tetsuhiro Yoshino, Ryutaro Arita, Yuko Horiba and Kenji Watanabe

    Citation: BMC Complementary and Alternative Medicine 2019 19:68

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  21. Content type: Research article

    Epithelial-mesenchymal transition (EMT) is a vital process in cancer progression and metastasis. Yanggan Jiedu Sanjie (YGJDSJ) is Traditional Chinese Medicine formulation for liver cancer treatment. In the pre...

    Authors: Bing Hu, Hong-Mei An, Xia Yan, Jia-Lu Zheng, Xiao-Wei Huang and Miao Li

    Citation: BMC Complementary and Alternative Medicine 2019 19:67

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  22. Content type: Research article

    The use of medications, including herbal medicines during breastfeeding is always a concern among women. Currently, there is no published evidence on whether Sierra Leonean women use herbal medicine during bre...

    Authors: Peter Bai James, Angela Isata Kaikai, Abdulai Jawo Bah, Amie Steel and Jon Wardle

    Citation: BMC Complementary and Alternative Medicine 2019 19:66

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  23. Content type: Research article

    Herbal medicine has become the panacea for many rural pregnant women in Ghana despite the modern western antenatal care which has developed in most parts of the country. To our knowledge, previous studies inve...

    Authors: Prince Peprah, Williams Agyemang-Duah, Francis Arthur-Holmes, Hayford Isaac Budu, Emmanuel Mawuli Abalo, Reforce Okwei and Julius Nyonyo

    Citation: BMC Complementary and Alternative Medicine 2019 19:65

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  24. Content type: Research article

    We investigated the effects of a berry mixture formula (modified Ojayeonjonghwan (Wuzi Yanzong Wan, MO formula) on detrusor overactivity (DO).

    Authors: Sangrak Bae, Kyu Won Lee, Hyun Cheol Jeong, Bong Hee Park, Woong Jin Bae, Chang Hee Han and Sae Woong Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:64

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  25. Content type: Research article

    Physical activity is an important part of the diabetes management plan. However, the effects caused by different training durations and styles of Tai Chi have not been evaluated. We conducted an updated system...

    Authors: Ting-Wei Xia, Yue Yang, Wei-Hong Li, Zhao-Hui Tang, Zong-Run Li and Li-Jun Qiao

    Citation: BMC Complementary and Alternative Medicine 2019 19:63

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  26. Content type: Research article

    Access to and advice on Complementary and Alternative Medicine (CAM) are uncommon within Swedish conventional cancer care and little is known about cancer patients’ own use of CAM. The aim of this cross-sectio...

    Authors: Kathrin Wode, Roger Henriksson, Lena Sharp, Anna Stoltenberg and Johanna Hök Nordberg

    Citation: BMC Complementary and Alternative Medicine 2019 19:62

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  27. Content type: Research article

    This systematic review evaluates the use of manual therapy for clinical conditions in the pediatric population, assesses the methodological quality of the studies found, and synthesizes findings based on healt...

    Authors: Carol Parnell Prevost, Brian Gleberzon, Beth Carleo, Kristian Anderson, Morgan Cark and Katherine A. Pohlman

    Citation: BMC Complementary and Alternative Medicine 2019 19:60

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  28. Content type: Research article

    Despite the reported health effects of cardamom on dyslipidemia, hepatomegaly, and fasting hyperglycemia, no human research has studied its potency in non-alcoholic fatty liver disease (NAFLD) as the hepatic p...

    Authors: Milad Daneshi-Maskooni, Seyed Ali Keshavarz, Mostafa Qorbani, Siavash Mansouri, Seyed Moayed Alavian, Mahtab Badri-Fariman, Seyed Ali Jazayeri-Tehrani and Gity Sotoudeh

    Citation: BMC Complementary and Alternative Medicine 2019 19:59

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  29. Content type: Study protocol

    Practitioners of complementary and alternative medicine have suggested that acupuncture could alleviate poststroke shoulder pain, based on the clinical evidence. This study protocol is aimed at showing the eff...

    Authors: Seungwon Shin, Sung Pil Yang, Ami Yu, Junghee Yoo, Sung Min Lim and Euiju Lee

    Citation: BMC Complementary and Alternative Medicine 2019 19:58

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  30. Content type: Research article

    Prolonged hyperuricemia is associated with kidney disease or gouty arthritis. Whether Yokuininto, a commercially available Kampo medicine that has been used for osteoarthritis or rheumatoid arthritis, can exhi...

    Authors: Seung Hoon Lee, Ho-Sung Lee, Gunhyuk Park, Sung-Man Oh and Dal-Seok Oh

    Citation: BMC Complementary and Alternative Medicine 2019 19:57

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  31. Content type: Research article

    Enantia chlorantha is a plant belonging to Annonaceae Family. The Barks and leaves are used traditionally to treat infectious diseases. Earlier studies highlighted the antibacterial activity of stem barks methano...

    Authors: Rebeca Madeleine Ebelle Etame, Raymond Simplice Mouokeu, Frank Stève Monthe Poundeu, Igor Kenfack Voukeng, Cedric Laurel Pouaha Cidjeu, Alembert Tchinda Tiabou, Abel Joel Gbaweng Yaya, Rosalie Anne Ngono Ngane, Jules Roger Kuiate and François Xavier Etoa

    Citation: BMC Complementary and Alternative Medicine 2019 19:56

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  32. Content type: Research article

    Mulberry is a Korean medicinal herb that shows effective prevention and treatment of obesity and diabetes. Bioconversion is the process of producing active ingredients from natural products using microorganism...

    Authors: Sang-Hyuk Jung, Joo-Hui Han, Hyun-Soo Park, Do-Hyung Lee, Seok Jin Kim, Hyun So Cho, Jong Seong Kang and Chang-Seon Myung

    Citation: BMC Complementary and Alternative Medicine 2019 19:55

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  33. Content type: Research article

    We previously reported that tacrolimus (Tac) does not decrease T helper 17 cells (Th17) response in kidney transplantation. In this study, we evaluated whether Resveratrol (Resv) has immunosuppressive effects ...

    Authors: Kyoung Chan Doh, Bo-Mi Kim, Kyoung Woon Kim, Byung Ha Chung and Chul Woo Yang

    Citation: BMC Complementary and Alternative Medicine 2019 19:54

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  34. Content type: Research article

    Ephedra chilensis K Presl, known locally as pingo–pingo, is a Chilean endemic plant used in traditional medicine as an anti-inflammatory and used in other treatments. However, unlike for the other Ephedra species...

    Authors: Marco Mellado, Mauricio Soto, Alejandro Madrid, Iván Montenegro, Carlos Jara-Gutiérrez, Joan Villena, Enrique Werner, Patricio Godoy and Luis F. Aguilar

    Citation: BMC Complementary and Alternative Medicine 2019 19:53

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  35. Content type: Research article

    Senecio serratuloides DC is used in folk medicine for treating hypertension, skin disorders, internal and external sores, rashes, burns and wounds. This study aimed at investigating the antihypertensive effects o...

    Authors: Charlotte Mungho Tata, Constance Rufaro Sewani-Rusike, Opeoluwa Oyehan Oyedeji, Ephraim Tobela Gwebu, Fikile Mahlakata and Benedicta Ngwenchi Nkeh-Chungag

    Citation: BMC Complementary and Alternative Medicine 2019 19:52

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  36. Content type: Research article

    In view of the increasing antibiotic resistance, the introduction of natural anti-infective agents has brought a new era in the treatment of bacterially derived oral diseases.

    Authors: Lamprini Karygianni, Manuel Cecere, Aikaterini Argyropoulou, Elmar Hellwig, Alexios Leandros Skaltsounis, Annette Wittmer, Jörg Philipp Tchorz and Ali Al-Ahmad

    Citation: BMC Complementary and Alternative Medicine 2019 19:51

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  37. Content type: Research article

    This study investigated the protective effects of the Danshen (DS) and Sanqi (SQ) herb pair on cell survival in the human cardiovascular endothelial (EA.hy926) cell line exposed to injury.

    Authors: Xian Zhou, Valentina Razmovski-Naumovski, Antony Kam, Dennis Chang, Chun Guang Li, Kelvin Chan and Alan Bensoussan

    Citation: BMC Complementary and Alternative Medicine 2019 19:50

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  38. Content type: Research article

    Hordeum vulgare L (barley) contains numerous phenolic substances with proven anticancer, antioxidant and gastroprotective activities. Saccharification increases the functionality and bioavailability of these comp...

    Authors: Jong-Min Lim, Chang-Hyun Song, Su-Jin Park, Dong-Chan Park, Go-Woon Jung, Hyung-Rae Cho, Khawaja Muhammad Imran Bashir, Sae Kwang Ku and Jae-Suk Choi

    Citation: BMC Complementary and Alternative Medicine 2019 19:49

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  39. Content type: Research article

    Development of safe and effective chemopreventive agents is a winning strategy in reducing the morbidity and mortality of breast cancer. The current study was to investigate the mechanism-based chemopreventive...

    Authors: Jingwei Li, Xiaofei Liu, Hongzhi Chen, Ziyuan Sun, Hanhan Chen, Lei Wang, Xiaohui Sun and Xiangqi Li

    Citation: BMC Complementary and Alternative Medicine 2019 19:48

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  40. Content type: Research article

    Libidibia ferrea (L. ferrea) has been used in folk medicine to treat several conditions and to prevent cancer. This study performed a chromatographic analysis of the crude aqueous extract of Libidibia ferrea (Mar...

    Authors: Tamires Rocha Falcão, Cássio Alexandre Oliveira Rodrigues, Aurigena Antunes de Araújo, Caroline Addison Carvalho Xavier de Medeiros, Luiz Alberto Lira Soares, Magda Rhayanny Assunção Ferreira, Roseane Carvalho Vasconcelos, Raimundo Fernandes de Araújo Júnior, Maria Luiza Diniz de Sousa Lopes and Gerlane Coelho Bernardo Guerra

    Citation: BMC Complementary and Alternative Medicine 2019 19:47

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  41. Content type: Research article

    Quinoa is a food crop native to the Andes. The process of dehulling quinoa can produce approximately 8–12% husk, which is often discarded because it contains bitter saponin. Saponin derived from quinoa has bee...

    Authors: Xiaoyan Sun, Xiushi Yang, Peng Xue, Zhiguo Zhang and Guixing Ren

    Citation: BMC Complementary and Alternative Medicine 2019 19:46

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  42. Content type: Research article

    The root of Baliospermum montanum has been used as an ingredient of traditional Thai medicines for the treatments of several diseases including itching eczema, muscle and joint inflammation, and cancer. Few studi...

    Authors: Weerachai Pipatrattanaseree, Arunporn Itharat, Nichamon Mukkasombut and Ubonwan Saesiw

    Citation: BMC Complementary and Alternative Medicine 2019 19:45

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  43. Content type: Research article

    Carica papaya leaves have been used for traditional treatment of dengue fever and have been reported to exhibit an immunomodulatory activity by affecting the level of cytokine production in vitro and in vivo. Due...

    Authors: Nor Azrina Norahmad, Mohd Ridzuan Mohd Abd Razak, Norazlan Mohmad Misnan, Nur Hana Md Jelas, Umi Rubiah Sastu, Amirrudin Muhammad, Tiffiny Chau Dee Ho, Bazilah Jusoh, Nor Azlina Zolkifli, Ravindran Thayan, Adiratna Mat Ripen, Murizal Zainol and Ami Fazlin Syed Mohamed

    Citation: BMC Complementary and Alternative Medicine 2019 19:44

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  44. Content type: Research article

    Sageretia thea (S. thea) has been used as the medicinal plant for treating hepatitis and fevers in Korea and China. Recently, anticancer activity of S. thea has been reported, but the potential mechanism for the ...

    Authors: Ha Na Kim, Gwang Hun Park, Su Bin Park, Jeong Dong Kim, Hyun Ji Eo, Ho-Jun Son, Jeong Ho Song and Jin Boo Jeong

    Citation: BMC Complementary and Alternative Medicine 2019 19:43

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  45. Content type: Research article

    There are no published studies regarding the efficacy of traditional Chinese medicine (TCM) for the prevention of osteoporotic fracture. Therefore, we conducted this nationwide, population-based cohort study t...

    Authors: Yu-Chi Wang, Jen-Huai Chiang, Hsin-Cheng Hsu and Chun-Hao Tsai

    Citation: BMC Complementary and Alternative Medicine 2019 19:42

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  46. Content type: Research article

    This study aimed to elucidate the effects and mechanisms of Radix Linderae (RL) extracts on a mouse model of diabetic bladder dysfunction (DBD), especially on later decompensated phase.

    Authors: Xufeng Yang, Dawei Lian, Pinglong Fan, Yifei Xu, Jing Wang, Fangjun Chen, Huanling Lai, Weiwen Jiang, Linjie Zhang, Ping Huang and Hongying Cao

    Citation: BMC Complementary and Alternative Medicine 2019 19:41

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  47. Content type: Research article

    Alzheimer’s disease (AD) and osteoporosis are progressive diseases that affect the elderly population. Both conditions are associated with fracture risk that is greater than twice that of the healthy populatio...

    Authors: Mustafa F. Alkhouli, Jun Hung, Michaela Squire, Miranda Anderson, Monica Castro, Jeganathan R. Babu, Layla Al-Nakkash, Tom L. Broderick and Jeffrey H. Plochocki

    Citation: BMC Complementary and Alternative Medicine 2019 19:39

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