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  1. Content type: Research article

    Ficus vasta Forssk. (Moraceae) is traditionally used for the treatment of various ailments; nonetheless, this species has been poorly studied to date. This work aimed to characterize the phenolic profile and to e...

    Authors: Maria Fernanda Taviano, Khaled Rashed, Angela Filocamo, Francesco Cacciola, Paola Dugo, Luigi Mondello, Carlo Bisignano, Rosaria Acquaviva, Manuela D’Arrigo and Natalizia Miceli

    Citation: BMC Complementary and Alternative Medicine 2018 18:161

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  2. Content type: Research article

    Complementary and alternative medicines (CAM) are sometimes used by individuals who desire to improve the outcomes of their fertility treatment and/or mental health during fertility treatment. However, there i...

    Authors: Skye A. Miner, Stephanie Robins, Yu Jia Zhu, Kathelijne Keeren, Vivian Gu, Suzanne C. Read and Phyllis Zelkowitz

    Citation: BMC Complementary and Alternative Medicine 2018 18:158

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  3. Content type: Study protocol

    Knee Osteoarthritis (KOA) is a very common condition with prevalence rising with age. It is a major contributor to global disability and has a large socioeconomic burden worldwide. Conservative therapies have ...

    Authors: Regina Wing Shan Sit, Ricky Wing Keung Wu, Kenneth Dean Reeves, David Rabago, Dicken Cheong Chun Chan, Benjamin Hon Kei Yip, Vincent Chi Ho Chung and Samuel Yeung Shan Wong

    Citation: BMC Complementary and Alternative Medicine 2018 18:157

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  4. Content type: Research article

    Oxidative stress and renal apoptosis play a significant role in the progression of diabetic nephropathy. The tubers of Pueraria tuberosa (Roxb. ex Willd.) DC. has been traditionally used as anti-ageing and health...

    Authors: Rashmi Shukla, Somanshu Banerjee and Yamini B. Tripathi

    Citation: BMC Complementary and Alternative Medicine 2018 18:156

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  5. Content type: Research article

    Few studies have investigated the prevalence and characteristics of potentially inappropriate Kampo medication use among elderly ambulatory patients taking any prescribed Kampo medications.

    Authors: Junpei Komagamine and Kazuhiko Hagane

    Citation: BMC Complementary and Alternative Medicine 2018 18:155

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  6. Content type: Research article

    Since oxidative stress and inflammation are two linked factors in the pathogenesis of several human diseases. Thus identification of effective treatment is of great importance. Edible mushroom and microalgae a...

    Authors: Marwa M. Abu-Serie, Noha H. Habashy and Wafaa E. Attia

    Citation: BMC Complementary and Alternative Medicine 2018 18:154

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  7. Content type: Research article

    The significant use of traditional and complementary medicine (T&CM) by cancer survivors is well documented. The aim of this study was to explore cancer survivors’ views on integrating T&CM services with conve...

    Authors: Jennifer Hunter, Jane Ussher, Chloe Parton, Andrew Kellett, Caroline Smith, Geoff Delaney and Eleanor Oyston

    Citation: BMC Complementary and Alternative Medicine 2018 18:153

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  8. Content type: Research article

    Breast cancer is the most common cancer in women and affects 1.38 million women worldwide per year. Antiestrogens such as tamoxifen, a selective estrogen receptor (ER) modulator, are widely used in clinics to ...

    Authors: Yu-Shih Lin, Yin-Yin Lin, Yao-Hsu Yang, Chun-Liang Lin, Feng-Che Kuan, Cheng-Nan Lu, Geng-He Chang, Ming-Shao Tsai, Cheng-Ming Hsu, Reming-Albert Yeh, Pei-Rung Yang, I-Yun Lee, Li-Hsin Shu, Yu-Ching Cheng, Hung-Te Liu, Kuan-Der Lee…

    Citation: BMC Complementary and Alternative Medicine 2018 18:152

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  9. Content type: Research article

    Dental caries remains a serious problem due to its detrimental effects on individual health and quality of life. The bulbs of Myrmecodia pendans (Merr & Perry), native plants of Papua, have been used as natural r...

    Authors: Meirina Gartika, Hening T. Pramesti, Dikdik Kurnia and Mieke H. Satari

    Citation: BMC Complementary and Alternative Medicine 2018 18:151

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  10. Content type: Research article

    Sheng Jiang San (SJS), a multi-herb formulation, is used in treating high fever, thirsty and anxiety in ancient China and it is sometimes used to treat seasonal influenza nowadays. However, there is no evidenc...

    Authors: Tianbo Zhang, Mengjie Xiao, Chun-Kwok Wong, Ka-Pun Chris Mok, Xin Zhao, Huihui Ti and Pang-Chui Shaw

    Citation: BMC Complementary and Alternative Medicine 2018 18:150

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  11. Content type: Research article

    The potential toxicity of Chinese herbal medicine has attracted more attention in recent years. Jueyin granules (JYG), a polyherbal formula, have been proven to be an effective agent for treating psoriasis in bot...

    Authors: Yu Chen, Dong-jie Guo, Hui Deng, Min-feng Wu, Ya-Nan Zhang, Su Li, Rong Xu, Jie Chen, Xing-xiu Jin, Bin Li, Qi Xu and Fu-lun Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:148

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  12. Content type: Research article

    Natural product is one of the most important sources of drugs used in pharmaceutical therapeutics. Artemisia capillaris has been traditionally used as a hepatoprotective and anti-inflammatory agent. In this study...

    Authors: Juyoung Kim, Kyung Hee Jung, Hong Hua Yan, Min Ji Cheon, Sunmi Kang, Xing Jin, Sunghyouk Park, Myung Sook Oh and Soon-Sun Hong

    Citation: BMC Complementary and Alternative Medicine 2018 18:147

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  13. Content type: Research article

    Human placenta hydrolysate (hPH) has been utilized to improve menopausal, fatigue, liver function. Its high concentration of bioactive substances is known to produce including antioxidant, anti-inflammatory an...

    Authors: Hyun-Jung Park, Hyun Soo Shim, Sunyoung Lee, Dae Hyun Hahm, Hyejung Lee, Chang Taek Oh, Hae Jung Han, Hyi Jeong Ji and Insop Shim

    Citation: BMC Complementary and Alternative Medicine 2018 18:149

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  14. Content type: Research article

    Fine particulate matter (PM2.5) is a major risk factor for the development and progression of atherosclerosis. Proliferation and infiltration of vascular smooth muscle cells (VSMCs) from the blood vessel media...

    Authors: Qiang Wan, Zhongyong Liu and Yuping Yang

    Citation: BMC Complementary and Alternative Medicine 2018 18:146

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  15. Content type: Research article

    Cryptococcal infections, besides being a problem for immunocompromised patients, are occasionally being a problem for immunocompetent patients. In addition, the lower susceptibility of this yeast to azoles is ...

    Authors: Daniela Scalas, Narcisa Mandras, Janira Roana, Roberta Tardugno, Anna Maria Cuffini, Valeria Ghisetti, Stefania Benvenuti and Vivian Tullio

    Citation: BMC Complementary and Alternative Medicine 2018 18:143

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  16. Content type: Research article

    Propolis, a polyphenol-rich natural product, has been used as a functional food in anti-inflammation. However, its bioactive components and mechanisms have not been fully elucidated.

    Authors: Huasong Chang, Wenwen Yuan, Haizhu Wu, Xusheng Yin and Hongzhuan Xuan

    Citation: BMC Complementary and Alternative Medicine 2018 18:142

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  17. Content type: Research article

    In a former meta-analysis review, acupuncture was considered a potentially effective treatment for dry eye syndrome (DES), but there were heterogeneities among the outcomes. We updated the meta-analysis and co...

    Authors: Bong Hyun Kim, Min Hee Kim, Se Hyun Kang and Hae Jeong Nam

    Citation: BMC Complementary and Alternative Medicine 2018 18:145

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  18. Content type: Research article

    The current treatment for human brucellosis requires a combination of antibiotics for long periods of time, and the reported incidence and prevalence of the disease vary widely in nomadic livestock of Mongolia...

    Authors: Tsevelmaa N, Narangerel B, Odgerel O, Dariimaa D and Batkhuu J

    Citation: BMC Complementary and Alternative Medicine 2018 18:144

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  19. Content type: Research article

    Terminalia chebula Retz. (Combretaceae) is a traditional herbal medicine that is widely used in the treatment of diabetes, immunodeficiency diseases, and stomach ulcer in Asia. However, the anti-amnesic effect of...

    Authors: Min-Soo Kim, Dong Young Lee, Jun Lee, Hyun Woo Kim, Sang Hyun Sung, Jung-Soo Han and Won Kyung Jeon

    Citation: BMC Complementary and Alternative Medicine 2018 18:136

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  20. Content type: Research article

    Cancer patients often suffer from emotional distress as a result of the oncological process. The purpose of our study was to determine whether practice of Jacobson’s relaxation technique reduced consumption of...

    Authors: Paula Parás-Bravo, Cristina Alonso-Blanco, María Paz-Zulueta, Domingo Palacios-Ceña, Carmen María Sarabia-Cobo, Manuel Herrero-Montes, Ester Boixadera-Planas and César Fernández-de-las-Peñas

    Citation: BMC Complementary and Alternative Medicine 2018 18:139

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  21. Content type: Research article

    Brazilian green propolis is produced by mixing secretions from Africanized honey bees with exudate, mainly from Baccharis dracunculifolia. Brazilian propolis is especially rich in flavonoids and cinammic acid der...

    Authors: Hiroshi Kitamura, Natsuko Saito, Junpei Fujimoto, Ken-ichi Nakashima and Daisuke Fujikura

    Citation: BMC Complementary and Alternative Medicine 2018 18:138

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  22. Content type: Research article

    Solanum aculeastrum fruits are used by some cancer sufferers as a form of alternative treatment. Scientific literature is scarce concerning its anticancer activity, and thus the aim of the study was to assess the...

    Authors: Trevor Burger, Tsholofelo Mokoka, Gerda Fouché, Paul Steenkamp, Vanessa Steenkamp and Werner Cordier

    Citation: BMC Complementary and Alternative Medicine 2018 18:137

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  23. Content type: Research article

    Herba Siegesbeckiae (HS, Xixiancao in Chinese) is a commonly used traditional Chinese medicinal herb for soothing joints. In ancient materia medica books, HS is recorded to be the aerial part of Siegesbeckia pube...

    Authors: Hui Guo, Yi Zhang, Brian Chi-Yan Cheng, Mei-Yuk Lau, Xiu-Qiong Fu, Ting Li, Tao Su, Pei-Li Zhu, Yuen-Cheung Chan, Anfernee Kai-Wing Tse, Tao Yi, Hu-Biao Chen and Zhi-Ling Yu

    Citation: BMC Complementary and Alternative Medicine 2018 18:141

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  24. Content type: Research article

    Medicinal plants have been founded as traditional herbal medicine worldwide. Most of the plant’s therapeutic properties are due to the presence of secondary metabolites such as alkaloids, glycosides, tannins a...

    Authors: Hazir Rahman, Ilyas Khan, Anwar Hussain, Abdelaaty Abdelaziz Shahat, Abdul Tawab, Muhammad Qasim, Muhammad Adnan, Mansour S. Al-Said, Riaz Ullah and Shahid Niaz Khan

    Citation: BMC Complementary and Alternative Medicine 2018 18:140

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  25. Content type: Research article

    Schistosomiasis is an acute and chronic zoonotic parasitic disease caused by trematode worms. The host inflammatory response to schistosome eggs leads to perioval granulomata formation, mainly in the liver and...

    Authors: Dina M. Metwally, Ebtesam M. Al-Olayan, Mohammad Alanazi, Sanaa B. Alzahrany and Abdelhabib Semlali

    Citation: BMC Complementary and Alternative Medicine 2018 18:135

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  26. Content type: Research article

    Radix Paeoniae Rubra (RPR), a traditional Chinese herb, has anti-inflammatory and immuno-regulatory properties. This study explored the effects of RPR on stimulation of osteoclast differentiation in RAW264.7 c...

    Authors: Huey-En Tzeng, Chun-Hao Tsai, Tin-Yun Ho, Chin-Tung Hsieh, Shen-Chieh Chou, Yi-Ju Lee, Gregory J. Tsay, Po-Hao Huang and Yi-Ying Wu

    Citation: BMC Complementary and Alternative Medicine 2018 18:132

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  27. Content type: Study protocol

    Sinew acupuncture is a new modality of acupuncture in which needles are inserted into acupoints, ashi points or spasm points of sinew and muscles along the meridian sinew pathway. A previous observational stud...

    Authors: Kwok Yin Au, Haiyong Chen, Wing Chung Lam, Chiu On Chong, Andrew Lau, Varut Vardhanabhuti, Kin Cheung Mak, Fei Jiang, Wing Yi Lam, Fung Man Wu, Hiu Ngok Chan, Yan Wah Ng, Bacon Fung-Leung Ng, Eric Tat-Chi Ziea and Lixing Lao

    Citation: BMC Complementary and Alternative Medicine 2018 18:133

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  28. Content type: Research article

    The medicinal orchid Dendrobium moniliforme contains water-soluble polysaccharides, phenanthrenes, bibenzyl derivatives, and polyphenol compounds. This study explored the antioxidant and cytotoxic activities of D...

    Authors: Mukti Ram Paudel, Mukesh Babu Chand, Basant Pant and Bijaya Pant

    Citation: BMC Complementary and Alternative Medicine 2018 18:134

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  29. Content type: Research article

    Previously, we reported that ChondorT showed significant anti-arthritis and anti-inflammatory effects. ChondroT, a new herbal medication, consists of the water extracts of Osterici Radix, Lonicerae Folium, Angeli...

    Authors: Jiwon Jeong, Kiljoon Bae, Sun-Gil Kim, Dongwook Kwak, Young-Joo Moon, Chan-Hun Choi, Young-Ran Kim, Chang-Su Na and Seon-Jong Kim

    Citation: BMC Complementary and Alternative Medicine 2018 18:131

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  30. Content type: Research article

    There is limited research regarding patients’ profiles and consumer attitudes and habits of osteopathy in Spain. The purpose of this study was to profile patients who regularly receive osteopathic care in Spai...

    Authors: Gerard Alvarez Bustins, Pedro-Victor López Plaza and Sonia Roura Carvajal

    Citation: BMC Complementary and Alternative Medicine 2018 18:129

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  31. Content type: Research article

    Houttuynia cordata Thunb. and Phyllanthus emblica Linn. are native plants with medicinal and nutritive significance in Asia. The present study was aimed at evaluating antiproliferative effects on human cancer cel...

    Authors: Piyawan Kumnerdkhonkaen, Somprasong Saenglee, Md. Ali Asgar, Gulsiri Senawong, Kanoknan Khongsukwiwat and Thanaset Senawong

    Citation: BMC Complementary and Alternative Medicine 2018 18:130

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  32. Content type: Research article

    Cancer and inflammation are associated with cachexia. Withania somnifera (W. somnifera) possesses antioxidant and anti-inflammatory potential. We investigated the potential of an aqueous extract of the root of W....

    Authors: Dhaneshree Bestinee Naidoo, Anil Amichund Chuturgoon, Alisa Phulukdaree, Kanive Parashiva Guruprasad, Kapaettu Satyamoorthy and Vikash Sewram

    Citation: BMC Complementary and Alternative Medicine 2018 18:126

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  33. Content type: Research article

    Therapeutic use of leaves of M. oleifera has been evaluated in diabetes because of its possible capacity to decrease blood glucose and lipids concentration after ingestion, as result of the polyphenols content an...

    Authors: A. Villarruel-López, D. A. López-de la Mora, O. D. Vázquez-Paulino, A. G. Puebla-Mora, Ma R. Torres-Vitela, L. A. Guerrero-Quiroz and K. Nuño

    Citation: BMC Complementary and Alternative Medicine 2018 18:127

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  34. Content type: Research article

    Lysimachia christinae Hance is a traditional Chinese medicine with diuretic, detumescent, and detoxifying effects. Our aimed to optimize the extraction protocol to maximize the yield of flavonoids from Lysimachia...

    Authors: Ning-hua Wu, Zhi-qiang Ke, Shan Wu, Xiao-song Yang, Qing-jie Chen, Sheng-tang Huang and Chao Liu

    Citation: BMC Complementary and Alternative Medicine 2018 18:128

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  35. Content type: Research article

    Use of multifunctional drugs with neurotrophic supporting and oxidative stress suppressing activity may be considered a therapeutic strategy to protect or repair cellular damage caused during the progression o...

    Authors: Hyun Ah Lee, Ji Eun Kim, Ji Eun Sung, Woo Bin Yun, Dong Seob Kim, Hee Seob Lee, Jin Tae Hong and Dae Youn Hwang

    Citation: BMC Complementary and Alternative Medicine 2018 18:125

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  36. Content type: Research article

    Patients are free to choose conventional or Korean medicine treatment under the dual medical system in Korea, and the prevalence of patients who choose Korean medicine treatment for whiplash-associated disorde...

    Authors: Nohyeon Kim, Byung-Cheul Shin, Joon-Shik Shin, Jinho Lee, Yoon Jae Lee, Me-riong Kim, Eui-Hyoung Hwang, Chan Yung Jung, Diana Ruan and In-Hyuk Ha

    Citation: BMC Complementary and Alternative Medicine 2018 18:124

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  37. Content type: Research article

    Alzheimer’s disease (AD), one of the major causes of dementia, is an overwhelming neurodegenerative disease that particularly affects the brain, leading to memory loss and impairment of language and judgment c...

    Authors: A. S. M. Ali Reza, Mohammad Shahadat Hossain, Sharmin Akhter, Md. Rezanur Rahman, Mst. Samima Nasrin, Md. Josim Uddin, Golam Sadik and A. H. M. Khurshid Alam

    Citation: BMC Complementary and Alternative Medicine 2018 18:123

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  38. Content type: Research article

    Crocin (CRO), chlorogenic acid (CGA), geniposide (GEN), and quercetin (QUE) are all natural compounds with anti-obesity properties, in particular, hypolipidemic effects, which have been widely used for the tre...

    Authors: Ennian Leng, Yuan Xiao, Zhentao Mo, Yiqi Li, Yueyue Zhang, Xiaosi Deng, Min Zhou, Chaochao Zhou, Zengxuan He, Jingyi He, Lu Xiao, Junming Li and Wenna Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:122

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  39. Content type: Research article

    Chinese herbal injections (CHIs) are prepared by extracting and purifying effective substances from herbs (or decoction pieces) using modern scientific techniques and methods. CHIs combined with aspirin + anti...

    Authors: Shi Liu, Jia-Rui Wu, Dan Zhang, Kai-Huan Wang, Bing Zhang, Xiao-Meng Zhang, Di Tan, Xiao-Jiao Duan, Ying-Ying Cui and Xin-Kui Liu

    Citation: BMC Complementary and Alternative Medicine 2018 18:120

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  40. Content type: Research article

    Cucumis sativus L. (cucumber), from the family Cucurbitaceae, is a therapeutic plant with various pharmacological benefits, broadly utilized as a part of complementary medicine (e.g., Unani, Ayurveda, Siddha, and...

    Authors: Raid Al Akeel, Ayesha Mateen, Khalid K. Alharbi, Abdullah A. Alyousef, Hazem M. Al-Mandeel and Rabbani Syed

    Citation: BMC Complementary and Alternative Medicine 2018 18:121

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  41. Content type: Research article

    A Chinese herbal formula, namely Jian-Pi-Yi-Shen (JPYS), has been clinically prescribed for patients with chronic kidney disease associated-anemia, and which can improve the patient’s immunological system. How...

    Authors: Jianping Chen, Amy G. W. Gong, Xiaoyan Liu, Zhonggui Li, Airong Qi, Tina T. X. Dong, Tiegang Yi, Karl W. K. Tsim and Shunmin Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:119

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  42. Content type: Research article

    Traditional, complementary and alternative medicine (TCAM) is seen as a way to provide healthcare in both developed and developing countries across the world. In Cambodia, there is a long tradition of using TC...

    Authors: Hattie Pearson, Tyler Fleming, Pheak Chhoun, Sovannary Tuot, Carinne Brody and Siyan Yi

    Citation: BMC Complementary and Alternative Medicine 2018 18:114

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  43. Content type: Research article

    Among the processes involved in the breast tumor microenvironment, angiogenesis and inflammation play a central role, and the main factors of these processes are the vascular endothelial growth factor (VEGF), ...

    Authors: Jéssica Alessandra-Perini, Jamila Alessandra Perini, Karina Cristina Rodrigues-Baptista, Roberto Soares de Moura, Antonio Palumbo Junior, Thiago Alves dos Santos, Pergentino José Cunha Souza, Luiz Eurico Nasciutti and Daniel Escorsim Machado

    Citation: BMC Complementary and Alternative Medicine 2018 18:116

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  44. Content type: Research article

    Bupleurum yinchowense Shan et Y. Li is widely used to treat depressive and anxiety disorders for hundreds of years in China. Total saikosaponins (TSS) is the major ingredient of Bupleurum yinchowense. A-amino-3-h...

    Authors: Xiuping Sun, Xianglei Li, Ruile Pan, Yanfeng Xu, Qiong Wang and Mingjing Song

    Citation: BMC Complementary and Alternative Medicine 2018 18:117

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  45. Content type: Research article

    Type 2 Diabetes (T2D) is a polygenic disease requiring a multipronged therapeutic approach. In the current scenario, the use of polyherbals is increasing among the diabetics. MD-1, a poly herbal formulation is...

    Authors: Srivani Telapolu, Mangathayaru Kalachavedu, Alan Mathew Punnoose and Dwarakanath Bilikere

    Citation: BMC Complementary and Alternative Medicine 2018 18:113

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  46. Content type: Research article

    We aimed to investigate the effectiveness of two different forms of dry pulsatile cupping in patients with chronic low back pain (cLBP) compared to medication on demand only in a three-armed randomized trial.

    Authors: M. Teut, A. Ullmann, M. Ortiz, G. Rotter, S. Binting, M. Cree, F. Lotz, S. Roll and B. Brinkhaus

    Citation: BMC Complementary and Alternative Medicine 2018 18:115

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  47. Content type: Research article

    Accumulating evidence suggests that Fructus Ligustri Lucidi (FLL) plays a beneficial role in preventing the development of osteoporosis. However, the effects of FLL on estrogen receptor (ER) α and ERβ expressions...

    Authors: Yu-qing Tang, Cheng Li, Xue-jiao Sun, Yi Liu, Xi-ting Wang, Yu-bo Guo, Li-li Wang, Ru-feng Ma, Jian-zhao Niu, Min Fu, Dong-wei Zhang and Yu Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:118

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  48. Content type: Research article

    Alzheimer’s disease (AD) is the most common form of dementia and the number of AD patients continues to increase worldwide. Components of the germ layer and bran of Brown rice (BR) help maintain good health an...

    Authors: Michiaki Okuda, Yuki Fujita, Takuya Katsube, Hiromasa Tabata, Katsumi Yoshino, Michio Hashimoto and Hachiro Sugimoto

    Citation: BMC Complementary and Alternative Medicine 2018 18:110

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  49. Content type: Research article

    Nowadays herbal products used in traditional medicine are sold in processed forms and thus morphological authentication is almost impossible. With herbal industry rapidly growing size, consumer safety becomes ...

    Authors: Maslin Osathanunkul, Rossarin Osathanunkul and Panagiotis Madesis

    Citation: BMC Complementary and Alternative Medicine 2018 18:111

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  50. Content type: Research article

    Intentional use of complementary and alternative medicine (CAM) has previously only been researched in small, possibly biased, samples. There seems to be a lack of scientific information regarding healthy indi...

    Authors: Agnete E. Kristoffersen, Trine Stub, Frauke Musial, Vinjar Fønnebø, Ola Lillenes and Arne Johan Norheim

    Citation: BMC Complementary and Alternative Medicine 2018 18:109

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