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  1. Albizia adianthifolia (Schum.) is medicinally used in Cameroon to manage bronchitis and skin diseases. Our previous study documented the antibacterial potential of its roots’ methanol extract. In this study, meth...

    Authors: Cedric F. Tchinda, Gaiëlle Sonfack, Ingrid K. Simo, İlhami Çelik, Igor K. Voukeng, Blaise K. Nganou, Gabin T. M. Bitchagno, Sultan Funda Ekti, Mathieu Tene, Pierre Tane, Veronique P. Beng and Victor Kuete

    Citation: BMC Complementary and Alternative Medicine 2019 19:120

    Content type: Research article

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  2. Staphylococcus aureus is a notorious pathogen which often causes nosocomial and community attained infections. These infections steadily increased after evolving the resistance due to indecorous practice of antib...

    Authors: Neelam Kumari, Snehlata Singh, Vandana Kumari, Siddhartha Kumar, Vinay Kumar and Antresh Kumar

    Citation: BMC Complementary and Alternative Medicine 2019 19:119

    Content type: Research article

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  3. Allium species are magnificently nutritious and are commonly used as a part of the diet in Iran. They have health enhancing benefits including anticancer properties due to the presence of numerous bioactive co...

    Authors: Kosar Vafaee, Soudeh Dehghani, Raheleh Tahmasvand, Farzaneh Saeed Abadi, Saeed Irian and Mona Salimi

    Citation: BMC Complementary and Alternative Medicine 2019 19:116

    Content type: Research article

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  4. Skin burn wound is a notable medical burden worldwide. Rapid and effective treatment of burnt skin is vital to fasten wound closure and healing properly. Amniotic graft and Aloe vera are widely used as wound mana...

    Authors: Md Shaifur Rahman, Rashedul Islam, Md Masud Rana, Lucas-Sebastian Spitzhorn, Mohammad Shahedur Rahman, James Adjaye and Sikder M. Asaduzzaman

    Citation: BMC Complementary and Alternative Medicine 2019 19:115

    Content type: Research article

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  5. Lactobacillus plantarum, a major species of Lactic Acid Bacteria (LAB), are capable of producing postbiotic metabolites (PM) with prominent probiotic effects that have been documented extensively for rats, poultr...

    Authors: Li-Oon Chuah, Hooi Ling Foo, Teck Chwen Loh, Noorjahan Banu Mohammed Alitheen, Swee Keong Yeap, Nur Elina Abdul Mutalib, Raha Abdul Rahim and Khatijah Yusoff

    Citation: BMC Complementary and Alternative Medicine 2019 19:114

    Content type: Research article

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  6. Embryonic neural stem cells (eNSCs) are immature precursors of the central nervous system (CNS), with self-renewal and multipotential differentiation capacities. These are regulated by endogenous and exogenous...

    Authors: Reza Mahmoudi, Majid Ghareghani, Kazem Zibara, Maryam Tajali Ardakani, Yahya Jand, Hassan Azari, Jafar Nikbakht and Amir Ghanbari

    Citation: BMC Complementary and Alternative Medicine 2019 19:113

    Content type: Research article

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  7. The plant Holarrhena floribunda (H. floribunda; G. Don) is indigenous to sub-Saharan Africa and is traditionally used to treat several ailments. The present study was carried out to isolate and characterize bioac...

    Authors: J. A. Badmus, O. E. Ekpo, A. A. Hussein, M. Meyer and D. C. Hiss

    Citation: BMC Complementary and Alternative Medicine 2019 19:112

    Content type: Research article

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  8. Atherosclerosis is a condition with the vascular accumulation of lipid plaques, and its main major contributing factor is endothelial injury induced by oxidized low-density lipoprotein (ox-LDL). Salidroside (S...

    Authors: Zhongsheng Zhu, Jinyu Li and Xiaorong Zhang

    Citation: BMC Complementary and Alternative Medicine 2019 19:111

    Content type: Research article

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  9. Many studies on the effect of saponin-rich Codonopsis lanceolata as a bioactive source for improving physical health have been performed. C. lanceolata contains triterpenoid saponins, including lancemasides. Thes...

    Authors: Young Seok Lee, HeeEun Kim, Jinhye Kim, Geun Hee Seol and Kwang-Won Lee

    Citation: BMC Complementary and Alternative Medicine 2019 19:110

    Content type: Research article

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  10. Berberine is an isoquinoline alkaloid extracted from various Berberis species which is widely used in East Asia for a wide range of symptoms. Recently, neuroprotective effects of berberine in Alzheimer’s disease ...

    Authors: Ning-Ning Yuan, Cui-Zan Cai, Ming-Yue Wu, Huan-Xing Su, Min Li and Jia-Hong Lu

    Citation: BMC Complementary and Alternative Medicine 2019 19:109

    Content type: Research article

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  11. Tuberculosis is a deadly disease caused by Mycobacterium species. The use of medicinal plants is an ancient global practice for the treatment and prevention of diverse ailments including tuberculosis. The aim of ...

    Authors: Abimbola O. Aro, Jean P. Dzoyem, Maurice D. Awouafack, Mamoalosi A. Selepe, Jacobus N. Eloff and Lyndy J. McGaw

    Citation: BMC Complementary and Alternative Medicine 2019 19:108

    Content type: Research article

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  12. Excessive activation of NLRP3 inflammasome and down-regulation of Sirt1/Smad3 deacetylation pathway play a significant role in the evolution of renal fibrosis. In China, it has been well known that Chinese her...

    Authors: Meng Wang, Liuyi Yang, Jing Yang and Chen Wang

    Citation: BMC Complementary and Alternative Medicine 2019 19:107

    Content type: Research article

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  13. The therapeutic use of Helleborus niger L. is manifold due to its specific phytochemical composition. Two compound groups, the ranunculin derivates including protoanemonin and the steroidal saponins, are also ass...

    Authors: Jennifer E. Felenda, Claudia Turek, Nora Mörbt, Anja Herrick, Margit B. Müller and Florian C. Stintzing

    Citation: BMC Complementary and Alternative Medicine 2019 19:105

    Content type: Research article

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  14. Despite advances in medical treatments, the proportion of the population suffering from alopecia is increasing, creating a need for new treatments to control hair loss and prevent balding. Treatments based on ...

    Authors: Gun-He Nam, Kyung-Jo Jo, Ye-Seul Park, Hye Won Kawk, Je-Geun Yoo, Jin Dong Jang, Sang Moon Kang, Sang-Yong Kim and Young-Min Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:104

    Content type: Research article

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  15. Chinese herbal bath therapy (CHBT) is a traditional external therapy that has been used for the treatment of uremic pruritus (UP) in China. We conducted a meta-analysis to evaluate the efficacy and safety of C...

    Authors: Wenxuan Xue, Yanhua Zhao, Mengyun Yuan and Zhiqiang Zhao

    Citation: BMC Complementary and Alternative Medicine 2019 19:103

    Content type: Research article

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  16. Calothamnus quadrifidus R.Br has many traditional uses and there are few reports about its chemical and biological activities. So our aim is to isolate the triterpenoidal compounds from dichloromethane fraction (...

    Authors: H. A. Ibrahim, M. R. Elgindi, R. R. Ibrahim and D. G. El-Hosari

    Citation: BMC Complementary and Alternative Medicine 2019 19:102

    Content type: Research article

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  17. Physalin A isolated from Physalis alkekengi var. franchetii has been known to have many pharmacological properties. However, its effect through the Nrf2 pathway has not yet been elucidated. In the present study, ...

    Authors: Ji Min Shin, Kyung-Mi Lee, Hee Ju Lee, Ji Ho Yun and Chu Won Nho

    Citation: BMC Complementary and Alternative Medicine 2019 19:101

    Content type: Research article

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  18. Obesity is a risk factor for many diseases including diabetes, cancer, arthritis, and cardiovascular diseases. Angiogenesis nourishes adipose tissues and contributes to obesity; it can be prevented by suppress...

    Authors: Muhammad Imran Khan, Jin Hyuk Shin and Jong Deog Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:100

    Content type: Research article

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  19. Type 2 diabetes (T2D) is a global pandemic, and contributes significantly to the increasing incidence of conditions such as cardiovascular disease (CVD). Postprandial plasma glucose measured 2-h after the star...

    Authors: Ratheesh Mohan, Svenia Jose, Johannah Mulakkal, Darla Karpinsky-Semper, Andrew G. Swick and I. M. Krishnakumar

    Citation: BMC Complementary and Alternative Medicine 2019 19:99

    Content type: Research article

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  20. Current therapeutic approaches to treat metastatic breast cancer, although effective, have shown many inadvertent side effects such as genotoxicity due to a lack of selectivity. Thus, these treatment plans are...

    Authors: Christopher Nguyen, Kiruthika Baskaran, Alaina Pupulin, Ivan Ruvinov, Ola Zaitoon, Sahibjot Grewal, Benjamin Scaria, Ali Mehaidli, Caleb Vegh and Siyaram Pandey

    Citation: BMC Complementary and Alternative Medicine 2019 19:98

    Content type: Research article

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  21. Endothelial dysfunction (ED) has been observed in individuals with metabolic syndrome (MetS) and contributes to the initiation and progression of atherosclerosis. The primary management of MetS involves lifest...

    Authors: Pingali Usharani, Padma Latha Merugu and Chandrasekhar Nutalapati

    Citation: BMC Complementary and Alternative Medicine 2019 19:97

    Content type: Research article

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  22. The purpose of this pilot study was to determine if a definitive clinical trial of thiamine supplementation was warranted in patients with acute heart failure. We hypothesized that thiamine, when added to stan...

    Authors: Howard A. Smithline, Michael Donnino, Fidela S. J. Blank, Richard Barus, Ryan A. Coute, Alexander B. Knee and Paul Visintainer

    Citation: BMC Complementary and Alternative Medicine 2019 19:96

    Content type: Research article

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  23. Traditional medicine has always been Pakistan’s cultural heritage, providing health care to a large part of its population. Thus, we aimed to assess and compare the knowledge, attitude, and perception about co...

    Authors: Mariam Ashraf, Hamid Saeed, Zikria Saleem, Hassaan Anwer Rathore, Fawad Rasool, Eman Tahir, Tooba Bhatti, Javeria Khalid, Iqra Bhatti and Ayesha Tariq

    Citation: BMC Complementary and Alternative Medicine 2019 19:95

    Content type: Research article

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  24. The brain is susceptible to methylmercury toxicity, which causes irreversible damage to neurons and glia and the leaf extract Dendropanax morbifera Léveille (DML) has various biological functions in the nervous s...

    Authors: Woosuk Kim, Dae Young Yoo, Hyo Young Jung, Jong Whi Kim, Kyu Ri Hahn, Hyun Jung Kwon, Miyoung Yoo, Sanghee Lee, Sung Min Nam, Yeo Sung Yoon, Dae Won Kim and In Koo Hwang

    Citation: BMC Complementary and Alternative Medicine 2019 19:94

    Content type: Research article

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  25. Complementary and alternative medicine (CAM) is a rather novel issue within public healthcare and health policy-making. CAM use in Europe is widespread, patient-initiated, and patient-evaluated, and the regula...

    Authors: Anita Salamonsen and Solveig Wiesener

    Citation: BMC Complementary and Alternative Medicine 2019 19:93

    Content type: Research article

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  26. To investigate the effects of the Alisma and Rhizoma decoction on nonalcoholic steatohepatitis (NASH) and to further shed light on the underlying mechanisms of the actions of the Alisma and Rhizoma decoction.

    Authors: Lijun Xu, Menghui Jing, Lijuan Yang, Lei Jin, Peiqiang Gong, Juan Lu, Hui Lin, Jinping Wang, Qin Cao and Yuanye Jiang

    Citation: BMC Complementary and Alternative Medicine 2019 19:92

    Content type: Research article

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  27. The extract of Celastrus orbiculatus (COE) have been studied for anti-Helicobacter pylori (H. pylori) activity and anti-cancer effects in vitro and in vivo. However, the molecular mechanism by which COE inhibits

    Authors: Yaodong Zhu, Lei Liu, Lei Hu, Wenqing Dong, Mei Zhang, Yanqing Liu and Ping Li

    Citation: BMC Complementary and Alternative Medicine 2019 19:91

    Content type: Research article

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  28. Papaver nudicaule belongs to the Papaveraceae family, which is planted as an annual herbaceous species generally for ornamental purpose. Papaver rhoeas in the same family has been reported to have various pharmac...

    Authors: Jae-Hyeon Oh, Miyong Yun, Dain Park, In Jin Ha, Chang-Kug Kim, Do-Wan Kim, Eun-Ok Kim and Seok-Geun Lee

    Citation: BMC Complementary and Alternative Medicine 2019 19:90

    Content type: Research article

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  29. Rubus coreanus fruit (RF) has been used as a traditional medicine formulation to treat various diseases including diarrhea, asthma, and cancer in East Asia (Korea, China, and Japan). RF, which is native to Korea,...

    Authors: Kyung Hye Seo, Ji Yeon Lee, Jeong-Yong Park, Gwi Yeong Jang, Hyung Don Kim, Young- Seob Lee and Dong Hwi Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:89

    Content type: Research article

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  30. Stevia rebaudiana Bertoni has various pharmacological actions, which includes antidiabetic, antioxidant, anti-inflammatory activities. The superoxide and consequently NADPH oxidase (Nox) are relevant targets invo...

    Authors: A. S. Isoyan, K. V. Simonyan, R. M. Simonyan, M. A. Babayan, G. M. Simonyan, V. A. Chavushyan and M. A. Simonyan

    Citation: BMC Complementary and Alternative Medicine 2019 19:88

    Content type: Research article

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  31. Whole-body electrical myostimulation (WB-EMS) is a relatively recent training methodology that has been extraordinarily used in recent years. However, there is a lack of consensus on the effectiveness of WB-EM...

    Authors: Alvaro Pano-Rodriguez, Jose Vicente Beltran-Garrido, Vicenç Hernández-González and Joaquim Reverter-Masia

    Citation: BMC Complementary and Alternative Medicine 2019 19:87

    Content type: Research article

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  32. The modified Si-Jun-Zi Decoction (SJZ), a Chinese medicine formula, is clinically used against multiple malignancies including colorectal cancer (CRC). This study aims to evaluate the effect of modified SJZ on...

    Authors: Jin-Yong Zhou, Min Chen, Cun-En Wu, Yu-Wen Zhuang, Yu-Gen Chen and Shen-Lin Liu

    Citation: BMC Complementary and Alternative Medicine 2019 19:86

    Content type: Research article

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  33. In 2011 there was a strengthening of European Union (EU) legislation on the licencing of herbal products which, in the UK, resulted in the introduction of the Traditional Herbal Registration (THR) scheme. This...

    Authors: R. Dickinson, M. C. Kennedy, D. K. Raynor, P. Knapp, M. Thomas and E. Adami

    Citation: BMC Complementary and Alternative Medicine 2019 19:85

    Content type: Research article

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  34. Fructus Psoraleae is the seed of Psoralea corylifolia Linn. Fructus Psoraleae has been shown to be effective in treating some skin diseases, such as vitiligo. As a main ingredient in five types of herbs in the Qu...

    Authors: Ang Li, Minhong Gao, Na Zhao, Ping Li, Jinguo Zhu and Wenfei Li

    Citation: BMC Complementary and Alternative Medicine 2019 19:84

    Content type: Case report

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  35. Integrative and complementary health approaches (ICHA) are often pursued by patients facing chronic illnesses. Most of the studies that investigated the factors associated with ICHA consumption have considered...

    Authors: Fabrice Berna, Anja S. Göritz, Amaury Mengin, Renaud Evrard, Jacques Kopferschmitt and Steffen Moritz

    Citation: BMC Complementary and Alternative Medicine 2019 19:83

    Content type: Research article

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  36. Cytinus is small genus of endophytic parasitic plants distributed in South Africa, Madagascar, and in the Mediterranean region. In the latter area, two species occur, Cytinus hypocistis and C. ruber, distinguishe...

    Authors: Giuseppantonio Maisetta, Giovanna Batoni, Pierluigi Caboni, Semih Esin, Andrea C. Rinaldi and Paolo Zucca

    Citation: BMC Complementary and Alternative Medicine 2019 19:82

    Content type: Research article

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  37. Diabetic nephropathy (DN) is a common complication of diabetes mellitus (DM) that imposes an enormous burden on the healthcare system. Although some studies show that traditional Chinese medicine (TCM) treatme...

    Authors: Hsing-Yu Chen, Heng-Chih Pan, Yung-Chang Chen, Yu-Chun Chen, Yi-Hsuan Lin, Sien-Hung Yang, Jiun-Liang Chen and Hau-Tieng Wu

    Citation: BMC Complementary and Alternative Medicine 2019 19:81

    Content type: Research article

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  38. Organochalcogen compounds have attracted the interest of a multitude of studies for their promising Pharmacological and biological activities. The antioxidant activity and acute toxicity of an organoselenium c...

    Authors: Mohammad Ibrahim, Niaz Muhammad, Musadiq Ibrahim, Muhammad Idrees Khan, Muhammad Ishaq Ali Shah, Muhammad Said, Waliullah Khan, Jean Paul Kamdem and Joao Batista Teixeira Rocha

    Citation: BMC Complementary and Alternative Medicine 2019 19:80

    Content type: Research article

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  39. Methanol extract (MECN) of Clinacanthus nutans Lindau leaves (family Acanthaceae) demonstrated peripherally and centrally mediated antinociceptive activity via the modulation of opioid/NO-mediated, but cGMP-indep...

    Authors: Zainul Amiruddin Zakaria, Mohammad Hafiz Abdul Rahim, Mohd Hijaz Mohd Sani, Maizatul Hasyima Omar, Siew Mooi Ching, Arifah Abdul Kadir and Qamar Uddin Ahmed

    Citation: BMC Complementary and Alternative Medicine 2019 19:79

    Content type: Research article

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  40. Teaching Complementary and alternative medicine (CAM) in medical schools is becoming prevalent worldwide. Few studies have been conducted to evaluate medical students’ knowledge and attitude toward CAM. Theref...

    Authors: Ahmad M. Samara, Ethar R. Barabra, Hala N. Quzaih and Sa’ed H. Zyoud

    Citation: BMC Complementary and Alternative Medicine 2019 19:78

    Content type: Research article

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  41. Cordyceps is a traditional Chinese herb that produces various biopharmaceutical effects, including immune-enhancing effects. In this study, we prepared a Cordyceps mycelium culture extract (Paecilomyces hepiali, ...

    Authors: Su-Jin Jung, Eun-Soo Jung, Eun-Kyung Choi, Hong-Sig Sin, Ki-Chan Ha and Soo-Wan Chae

    Citation: BMC Complementary and Alternative Medicine 2019 19:77

    Content type: Research article

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  42. Music has been shown to improve health and quality of life. It was suggested that music may also have an impact on gait stability and fall risk. Yet, few studies have exploited music in the hospital setting, a...

    Authors: Julia Chabot, Olivier Beauchet, Shek Fung and Isabelle Peretz

    Citation: BMC Complementary and Alternative Medicine 2019 19:76

    Content type: Research article

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  43. The introduction of imatinib revolutionized the treatment of chronic myeloid leukaemia (CML), substantially extending patient survival. However, imatinib resistance is currently a clinical problem for CML. It ...

    Authors: Huayao Li, Lijuan Liu, Jing Zhuang, Cun Liu, Chao Zhou, Jing Yang, Chundi Gao, Gongxi Liu and Changgang Sun

    Citation: BMC Complementary and Alternative Medicine 2019 19:75

    Content type: Research article

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  44. Different plant parts of Roylea cinerea (D. Don) Baill. (Lamiaceae), Clematis grata Wall. (Ranunculaceae), Cornus capitata Wall. (Cornaceae) are traditionally used in the management of diabetes and various other ...

    Authors: Astha Bhatia, Balbir Singh, Rohit Arora and Saroj Arora

    Citation: BMC Complementary and Alternative Medicine 2019 19:74

    Content type: Research article

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  45. Complementary Medicine (CM) continues to thrive across many countries. Closely related to the continuing popularity of CM has been an increased number of enrolments at CM education institutions across the publ...

    Authors: Alastair C. Gray, Amie Steel and Jon Adams

    Citation: BMC Complementary and Alternative Medicine 2019 19:73

    Content type: Research article

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  46. Solidago chilensis (syn. microglossa) is a plant from the Asteraceae family widely distributed in South America and used to treat inflammatory diseases. In 2009, it was listed as one of the native medicinal herba...

    Authors: Elena L. A. Malpezzi-Marinho, Graziela R. Molska, Lyvia I. G. P. Freire, Cristiane I. Silva, Eduardo K. Tamura, Laís F. Berro, Carlos A. Parada and Eduardo Ary Villela Marinho

    Citation: BMC Complementary and Alternative Medicine 2019 19:72

    Content type: Research article

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  47. Ocimum gratissimum L. is a medicinal plant widely grown in tropical and subtropical regions with the leaf decoction usually taken in folk medicine to enhance erectile performance in men although the probable mech...

    Authors: Oluwafemi Adeleke Ojo, Adebola Busola Ojo, Babatunji Emmanuel Oyinloye, Basiru Olaitan Ajiboye, Omosola Olufisayo Anifowose, Ayodeji Akawa, Oluranti Esther Olaiya, Oluwaseun Ruth Olasehinde and Abidemi Paul Kappo

    Citation: BMC Complementary and Alternative Medicine 2019 19:71

    Content type: Research article

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