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  1. Content type: Research article

    Although alopecia affects the quality of life, its pathogenesis is unknown, because cellular interactions in the hair follicle are complex. Several authors have suggested using herbal medicine to treat alopeci...

    Authors: Jungtae Leem, Wonmo Jung, Yohwan Kim, Bonghyun Kim and Kyuseok Kim

    Citation: BMC Complementary and Alternative Medicine 2018 18:204

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  2. Content type: Research article

    Epithelial-to-mesenchymal transition (EMT) plays an important role in the progression of renal interstitial fibrosis, which finally leads to renal failure. Oleanolic acid (OA), an activator of NF-E2-related fa...

    Authors: Wei-ming He, Jia-qi Yin, Xu-dong Cheng, Xun Lu, Li Ni, Yi Xi, Gui-dong Yin, Guo-yuan Lu, Wei Sun and Ming-gang Wei

    Citation: BMC Complementary and Alternative Medicine 2018 18:205

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  3. Content type: Study protocol

    Uncomplicated urinary tract infections (UTI) are common in general practice and usually treated with antibiotics. This contributes to increasing resistance rates of uropathogenic bacteria. A previous trial sho...

    Authors: Kambiz Afshar, Nina Fleischmann, Guido Schmiemann, Jutta Bleidorn, Eva Hummers-Pradier, Tim Friede, Karl Wegscheider, Michael Moore and Ildikó Gágyor

    Citation: BMC Complementary and Alternative Medicine 2018 18:203

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  4. Content type: Research article

    Royal jelly (RJ), the exclusive food for the larva of queen honeybee, is regarded as the novel supplement to promote human health. The function of RJ may be attributed to its major and unique fatty acid, 10-hy...

    Authors: Yuan-Chang Yang, Wing-Ming Chou, Debora Arny Widowati, I-Ping Lin and Chi-Chung Peng

    Citation: BMC Complementary and Alternative Medicine 2018 18:202

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  5. Content type: Research article

    Cancer is one of the most frequently occurring diseases and is the second leading cause of death worldwide. In this study, anthraquinone derivatives (Compounds 1–5) were evaluated for their anti-cancer potenti...

    Authors: Vivek K. Bajpai, Md Badrul Alam, Khong Trong Quan, Hee-Jeong Choi, Hongyan An, Mi-Kyoung Ju, Sang-Han Lee, Yun Suk Huh, Young-Kyu Han and MinKyun Na

    Citation: BMC Complementary and Alternative Medicine 2018 18:200

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  6. Content type: Research article

    Mentha spicata (M. spicata) is a member of Lamiaceae that spreads mainly in the temperate and sub-temperate zones of the world. It is considered as a rich source of essential oils, which is widely used in pharmac...

    Authors: Sanaa K. Bardaweel, Boulanouar Bakchiche, Husam A. ALSalamat, Maria Rezzoug, Abdelaziz Gherib and Guido Flamini

    Citation: BMC Complementary and Alternative Medicine 2018 18:201

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  7. Content type: Research article

    The constant emergence of antibiotic resistant species and the adverse side effects of synthetic drugs are threatening the efficacy of the drugs that are currently in use. This study was aimed at investigating...

    Authors: Refilwe G. Kudumela, Lyndy J. McGaw and Peter Masoko

    Citation: BMC Complementary and Alternative Medicine 2018 18:199

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  8. Content type: Research article

    Evidence suggests that tocotrienols may benefit bone health in osteopenic women. However, their safety in this population has never been investigated. This study was to evaluate the safety of a 12-week supplem...

    Authors: Chwan-Li Shen, Shu Wang, Shengping Yang, Michael D. Tomison, Mehrnaz Abbasi, Lei Hao, Sheyenne Scott, Md Shahjalal Khan, Amanda W. Romero, Carol K. Felton and Huanbiao Mo

    Citation: BMC Complementary and Alternative Medicine 2018 18:198

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  9. Content type: Research article

    One of the molecular mechanisms involved in upper airway-related diseases is epithelial-to-mesenchymal transition (EMT). Olea europaea (OE) has anti-inflammatory properties and thus, great potential to prevent EM...

    Authors: Rabiatul Adawiyah Razali, Nik Ahmad Hafiz Nik Ahmad Eid, Turkambigai Jayaraman, Muhammad Asyrafi Amir Hassan, Nabilah Qistina Azlan, Nur Farhana Ismail, Nur Qisya Afifah Veronica Sainik, Muhammad Dain Yazid, Yogeswaran Lokanathan, Aminuddin Bin Saim and Ruszymah Bt Hj Idrus

    Citation: BMC Complementary and Alternative Medicine 2018 18:197

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  10. Content type: Research article

    Agastache rugosa (Fisch. & C.A.Mey.) Kuntze (Korean mint) is used to treat diverse types of human disorders in traditional medicine. In recent years, its non-fermented leaf extract (ARE) has been shown to possess...

    Authors: Daehyun Shin, Yoonjin Lee, Yu-Hua Huang, Hye-Won Lim, Kyounghee Jang, Dae-Duk Kim and Chang-Jin Lim

    Citation: BMC Complementary and Alternative Medicine 2018 18:196

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  11. Content type: Research article

    Coconut water has been commonly consumed as a beverage for its multiple health benefits while vinegar has been used as common seasoning and a traditional Chinese medicine. The present study investigates the po...

    Authors: Nurul Elyani Mohamad, Swee Keong Yeap, Boon-Kee Beh, Huynh Ky, Kian Lam Lim, Wan Yong Ho, Shaiful Adzni Sharifuddin, Kamariah Long and Noorjahan Banu Alitheen

    Citation: BMC Complementary and Alternative Medicine 2018 18:195

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  12. Content type: Research article

    It is widely accepted the key role of endothelium in the onset of many chronic and acute vascular and cardiovascular diseases.

    Authors: Chiara Bernardini, Augusta Zannoni, Martina Bertocchi, Irvin Tubon, Mercedes Fernandez and Monica Forni

    Citation: BMC Complementary and Alternative Medicine 2018 18:194

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  13. Content type: Research article

    Traditional Chinese medicine (TCM) has been used by Chinese patients and in many other countries worldwide. However, epidemiological reports and prescription patterns on children are few.

    Authors: Hwey-Fang Liang, Yao-Hsu Yang, Pau-Chung Chen, Hsing-Chun Kuo, Chia-Hao Chang, Ying-Hsiang Wang and Kuang-Ming Wu

    Citation: BMC Complementary and Alternative Medicine 2018 18:191

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  14. Content type: Research article

    Presumably, progression of developmental retinal vascular disorders is mainly driven by persistent ischemia/hypoxia. An investigation into vision-threatening retinal ischemia remains important. Our aim was to ...

    Authors: Wen-Haur Chao, Ming-Yi Lai, Hwai-Tzong Pan, Huei-Wen Shiu, Mi-Mi Chen and Hsiao-Ming Chao

    Citation: BMC Complementary and Alternative Medicine 2018 18:193

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  15. Content type: Research article

    The Nucleotide binding and oligomerization domain-like receptorfamily pyrin domain-containing 3 (NLRP3)-inflammasome plays an important role in various diseases, including a variety of kidney diseases. Naringi...

    Authors: Fenqin Chen, Guozhu Wei, Jiao Xu, Xiaoyu Ma and Qiuyue Wang

    Citation: BMC Complementary and Alternative Medicine 2018 18:192

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  16. Content type: Research article

    Although the inhibitory effect of mistletoe on cancer cell growth has been reported, the underlying mechanisms to explain its anti-proliferative activity are not fully studied. Thus, we elucidated the potentia...

    Authors: Su Bin Park, Gwang Hun Park, Ha Na Kim, Hun Min Song, Ho-Jun Son, Ji Ae Park, Hyun-Seok Kim and Jin Boo Jeong

    Citation: BMC Complementary and Alternative Medicine 2018 18:189

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  17. Content type: Research article

    In contrast to the guidelines of World Health Organization (WHO) and United States-Centers for Disease Control and prevention (US-CDC), the Chinese national guidelines recommend the use of steroids, intravenou...

    Authors: Dangui Zhang, Jieling Chen and William Ba-Thein

    Citation: BMC Complementary and Alternative Medicine 2018 18:190

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  18. Content type: Research article

    Zyflamend, a blend of herbal extracts, effectively inhibits tumor growth using preclinical models of castrate-resistant prostate cancer mediated in part by 5′-adenosine monophosphate-activated protein kinase (...

    Authors: Amber F. MacDonald, Ahmed Bettaieb, Dallas R. Donohoe, Dina S. Alani, Anna Han, Yi Zhao and Jay Whelan

    Citation: BMC Complementary and Alternative Medicine 2018 18:188

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  19. Content type: Research article

    The outbreak of MDR and XDR strains of Pseudomonas aeruginosa and increased resistance to infection in burn patients recommend the issue of infection control. In this research, we study ZOUSH herbal ointment for ...

    Authors: Maryam Meskini and Davoud Esmaeili

    Citation: BMC Complementary and Alternative Medicine 2018 18:185

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  20. Content type: Research article

    Although integrative medicine is gaining increasing attention and is claiming more and more its place in modern health care, it still plays a marginal role in conventional maternity care. The present study aim...

    Authors: Nikolas Schürger, Evelyn Klein, Alexander Hapfelmeier, Marion Kiechle and Daniela Paepke

    Citation: BMC Complementary and Alternative Medicine 2018 18:187

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  21. Content type: Research article

    Influenza infection is a major public health threat. The role of influenza A virus-induced inflammatory response in severe cases of this disease is widely recognized. Drug resistance and side effects of chemic...

    Authors: Parvaneh Mehrbod, Muna Ali Abdalla, Fatemeh Fotouhi, Masoumeh Heidarzadeh, Abimbola O. Aro, Jacobus N. Eloff, Lyndy J. McGaw and Folorunso O. Fasina

    Citation: BMC Complementary and Alternative Medicine 2018 18:184

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  22. Content type: Research article

    The prevalence of functional constipation (FC) is 3–27%, and FC has been reported to cause discomfort in daily life and various complications. The treatment for FC depends on laxatives, and thus, effective and...

    Authors: Hye-Yoon Lee, Oh-Jin Kwon, Jung-Eun Kim, Mikyeong Kim, Ae-Ran Kim, Hyo-Ju Park, Jung-Hyo Cho, Joo-Hee Kim and Sun-Mi Choi

    Citation: BMC Complementary and Alternative Medicine 2018 18:186

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  23. Content type: Research article

    Patients entering a treatment have expectancy to outcome based on their previous experience, the information received, and the credibility of the treatment. Once the treatment has started, patients may detect ...

    Authors: Ingrid Liodden, Are Hugo Pripp and Arne Johan Norheim

    Citation: BMC Complementary and Alternative Medicine 2018 18:183

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  24. Content type: Correction

    Following publication of the original article [1], the authors reported that there was an error in the acknowledgements.

    Authors: Gulzar Ahmad Bhat, Haseeb A. Khan, Abdullah S. Alhomida, Poonam Sharma, Rambir Singh and Bilal Ahmad Paray

    Citation: BMC Complementary and Alternative Medicine 2018 18:182

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    The original article was published in BMC Complementary and Alternative Medicine 2018 18:162

  25. Content type: Research article

    Anacardium occidentale L phenolic lipid (LDT11) is used in traditional medicine as anti-inflammatory, astringent, antidiarrheal, anti-asthmatic and depurative. Phenolic derivatives, such as anacardic acid, extrac...

    Authors: Marilen Queiroz de Souza, Isabella Márcia Soares Nogueira Teotônio, Fernanda Coutinho de Almeida, Gabriella Simões Heyn, Priscilla Souza Alves, Luiz Antônio Soares Romeiro, Riccardo Pratesi, Yanna Karla de Medeiros Nóbrega and Claudia B. Pratesi

    Citation: BMC Complementary and Alternative Medicine 2018 18:181

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  26. Content type: Research article

    Kaempferia parviflora (KP) is an herb found in the north of Thailand and used as a folk medicine for improving vitality. Current reports have shown the anti-cancer activities of KP. However, the anti-cancer effec...

    Authors: Suthasinee Paramee, Siriwoot Sookkhee, Choompone Sakonwasun, Mingkwan Na Takuathung, Pitchaya Mungkornasawakul, Wutigri Nimlamool and Saranyapin Potikanond

    Citation: BMC Complementary and Alternative Medicine 2018 18:178

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  27. Content type: Research article

    Aromatase inhibitors reduce breast cancer recurrence rates in postmenopausal women by about 30% compared with tamoxifen while treatments differ. Unfortunately, nearly half of women taking AIs report AI-associa...

    Authors: Inmaculada Conejo, Bella Pajares, Emilio Alba and Antonio Ignacio Cuesta-Vargas

    Citation: BMC Complementary and Alternative Medicine 2018 18:180

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  28. Content type: Research article

    Stevia (Stevia rebaudiana) natural, non-caloric sugar substitute is rich source of pharmacologically important glycoside stevioside that is linked to the pathology and complications of diabetes.

    Authors: Uswa Ahmad and Rabia Shabir Ahmad

    Citation: BMC Complementary and Alternative Medicine 2018 18:179

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  29. Content type: Research article

    Oroxylum indicum (L.) Kurz (O. indicum) is found in Thailand. It has been used for the treatment of obesity. This study aimed to investigate the effects of an O. indicum extract (OIE) on the adipogenic and biomol...

    Authors: Tanaporn Hengpratom, Gordon M. Lowe, Kanjana Thumanu, Siriporn Suknasang, Kanokwan Tiamyom and Griangsak Eumkeb

    Citation: BMC Complementary and Alternative Medicine 2018 18:177

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  30. Content type: Research article

    Advanced hepatobiliary cancers are highly lethal cancers that require precise prediction in clinical practice. Serum ferritin level increases in malignancy and high serum ferritin level is associated with poor...

    Authors: Anna Song, Wankyu Eo, Sehyun Kim, Bumsang Shim and Sookyung Lee

    Citation: BMC Complementary and Alternative Medicine 2018 18:176

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  31. Content type: Correction

    Following publication of the original article [1], the authors reported that there was an error in the acknowledgements. In this Correction, the incorrect and correct acknowledgements are shown.

    Authors: Gulzar Ahmad Bhat, Haseeb A. Khan, Abdullah S. Alhomida, Poonam Sharma, Rambir Singh and Bilal Ahmad Paray

    Citation: BMC Complementary and Alternative Medicine 2018 18:175

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    The original article was published in BMC Complementary and Alternative Medicine 2018 18:162

  32. Content type: Research article

    In the view of endemic avian influenza H9N2 infection in poultry, its zoonotic potential and emergence of antiviral resistance, two herbal plants, Ocimum sanctum and Acacia arabica, which are easily available thr...

    Authors: S. S. Ghoke, R. Sood, N. Kumar, A. K. Pateriya, S. Bhatia, A. Mishra, R. Dixit, V. K. Singh, D. N. Desai, D. D. Kulkarni, U. Dimri and V. P. Singh

    Citation: BMC Complementary and Alternative Medicine 2018 18:174

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  33. Content type: Research article

    Trichilia catigua A. Juss. (Meliaceae) is a species known as catuaba and used in folk medicine for the treatment of fatigue, stress, impotence and memory deficit. The main phytochemical compounds identified in th...

    Authors: Nadini Oliveira Martins, Isabella Modelli de Brito, Sandra Syomara O. Araújo, Giuseppina Negri, Elisaldo de Araújo Carlini and Fúlvio Rieli Mendes

    Citation: BMC Complementary and Alternative Medicine 2018 18:172

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  34. Content type: Research article

    Bidens pilosa and Dichrostachys cinerea extracts were investigated for the antibacterial properties against waterborne diarrhoeagenic bacteria.

    Authors: Pfarelo Daphney Shandukani, Shonisani Cathphonia Tshidino, Peter Masoko and Kgabo Maureen Moganedi

    Citation: BMC Complementary and Alternative Medicine 2018 18:171

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  35. Content type: Research article

    The collapse of mitochondrial membrane potential (ΔΨm) resulted in the cell apoptosis and heart failure. Xinshuitong Capsule (XST) could ameliorate left ventricular ejection fraction (LVEF), New York Heart Ass...

    Authors: Chunjiang Tan, Jianwei Zeng, Yanbin Wu, Jiahui Zhang and Wenlie Chen

    Citation: BMC Complementary and Alternative Medicine 2018 18:170

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  36. Content type: Research article

    Biofilms have great significance in healthcare-associated infections owing to their inherent tolerance and resistance to antimicrobial therapies. New approaches to prevent and treat unwanted biofilms are urgen...

    Authors: Luca De Vincenti, Yvana Glasenapp, Cristina Cattò, Federica Villa, Francesca Cappitelli and Jutta Papenbrock

    Citation: BMC Complementary and Alternative Medicine 2018 18:168

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  37. Content type: Research article

    Combining conventional drugs and traditional medicine may represent a useful approach to combating antibiotic resistance, which has become a serious threat to global public health. This study aimed to evaluate...

    Authors: Weifeng Yang, Jueling Liu, Biljana Blažeković, Yanan Sun, Shuhua Ma, Chuanyun Ren, Sanda Vladimir-Knežević, Chaohua Li, Yajun Xing, Guijie Tian and Yi Wang

    Citation: BMC Complementary and Alternative Medicine 2018 18:169

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  38. Content type: Research article

    It is well known that Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by memory deficits and cognitive decline. Amyloid-β (Aβ) deposition and synaptic dysfunction play importa...

    Authors: Jing-Hua Zhang, Lin-Jie Yu, Hui Yang, Zhen Hui, Su Jiang, Ling Chen, Yang Zhao, Su-Lei Wang, Yi Liu and Yun Xu

    Citation: BMC Complementary and Alternative Medicine 2018 18:167

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  39. Content type: Research article

    The use of herbal medicines during pregnancy is very high globally and previous studies have pointed out possible associations with adverse pregnancy outcomes. Nevertheless, the safety of herbal medicines in p...

    Authors: Collins Zamawe, Carina King, Hannah Maria Jennings and Edward Fottrell

    Citation: BMC Complementary and Alternative Medicine 2018 18:166

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  40. Content type: Research article

    Propolis is multicomponent substance collected by honeybees from various plants. It is known for numerous biological effects and is commonly used as ethanolic extract because most of active substances of propo...

    Authors: Loreta Kubiliene, Aiste Jekabsone, Modestas Zilius, Sonata Trumbeckaite, Daiva Simanaviciute, Rima Gerbutaviciene and Daiva Majiene

    Citation: BMC Complementary and Alternative Medicine 2018 18:165

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  41. Content type: Research article

    Homoharringtonine (HHT) is a natural alkaloid with potent antitumor activity, but its precise mechanism of action is still poorly understood.

    Authors: Qi Sun, Shiyue Li, Junjun Li, Qiuxia Fu, Zhongyuan Wang, Bo Li, Shan-Shan Liu, Zijie Su, Jiaxing Song and Desheng Lu

    Citation: BMC Complementary and Alternative Medicine 2018 18:164

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  42. Content type: Research article

    There are increasing interests in natural compounds for cancer chemoprevention. Blocking agents represent an important class of chemopreventive compounds. They prevent carcinogens from undergoing metabolic act...

    Authors: Ali M. El-Halawany, Hossam M. Abdallah, Ahmed R. Hamed, Hany Ezzat Khalil and Ameen M. Almohammadi

    Citation: BMC Complementary and Alternative Medicine 2018 18:163

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  43. Content type: Research article

    Diabetes mellitus is one of the major global health disorders increasing at an alarming rate in both developed and developing countries. The objective of this study was to assess the effect of aqueous extract of

    Authors: Gulzar Ahmad Bhat, Haseeb A. Khan, Abdullah S. Alhomida, Poonam Sharma, Rambir Singh and Bilal Ahmad Paray

    Citation: BMC Complementary and Alternative Medicine 2018 18:162

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    The Correction to this article has been published in BMC Complementary and Alternative Medicine 2018 18:182

    The Correction to this article has been published in BMC Complementary and Alternative Medicine 2018 18:175

  44. Content type: Research article

    Ficus vasta Forssk. (Moraceae) is traditionally used for the treatment of various ailments; nonetheless, this species has been poorly studied to date. This work aimed to characterize the phenolic profile and to e...

    Authors: Maria Fernanda Taviano, Khaled Rashed, Angela Filocamo, Francesco Cacciola, Paola Dugo, Luigi Mondello, Carlo Bisignano, Rosaria Acquaviva, Manuela D’Arrigo and Natalizia Miceli

    Citation: BMC Complementary and Alternative Medicine 2018 18:161

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  45. Content type: Research article

    This present study sought to assess the modulatory effects of five Nigerian traditional polyherbal in high fructose-fed, streptozotocin-induced (HF-STZ) Type 2 diabetes (T2D) in rats. T2D was achieved via fruc...

    Authors: O. E. Kale, O. B. Akinpelu, A. A. Bakare, F. O. Yusuf, R. Gomba, D. C. Araka, T. O. Ogundare, A. C. Okolie, O. Adebawo and O. Odutola

    Citation: BMC Complementary and Alternative Medicine 2018 18:160

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  46. Content type: Research article

    Antimicrobial resistance is a serious threat against humankind and the search for new therapeutics is needed. This study aims to investigate the antimicrobial and antioxidant activities of ethanol extracts and...

    Authors: Raissa Tioyem Nzogong, Fabrice Sterling Tchantchou Ndjateu, Steve Endeguele Ekom, Jules-Arnaud Mboutchom Fosso, Maurice Ducret Awouafack, Mathieu Tene, Pierre Tane, Hiroyuki Morita, Muhammad Iqbal Choudhary and Jean-de-Dieu Tamokou

    Citation: BMC Complementary and Alternative Medicine 2018 18:159

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  47. Content type: Research article

    Complementary and alternative medicines (CAM) are sometimes used by individuals who desire to improve the outcomes of their fertility treatment and/or mental health during fertility treatment. However, there i...

    Authors: Skye A. Miner, Stephanie Robins, Yu Jia Zhu, Kathelijne Keeren, Vivian Gu, Suzanne C. Read and Phyllis Zelkowitz

    Citation: BMC Complementary and Alternative Medicine 2018 18:158

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  48. Content type: Study protocol

    Knee Osteoarthritis (KOA) is a very common condition with prevalence rising with age. It is a major contributor to global disability and has a large socioeconomic burden worldwide. Conservative therapies have ...

    Authors: Regina Wing Shan Sit, Ricky Wing Keung Wu, Kenneth Dean Reeves, David Rabago, Dicken Cheong Chun Chan, Benjamin Hon Kei Yip, Vincent Chi Ho Chung and Samuel Yeung Shan Wong

    Citation: BMC Complementary and Alternative Medicine 2018 18:157

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  49. Content type: Research article

    Few studies have investigated the prevalence and characteristics of potentially inappropriate Kampo medication use among elderly ambulatory patients taking any prescribed Kampo medications.

    Authors: Junpei Komagamine and Kazuhiko Hagane

    Citation: BMC Complementary and Alternative Medicine 2018 18:155

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