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  1. Content type: Research article

    Chinese herbal formula Shaoyao Gancao decoction (SGD) is often used as an adjuvant with chemotherapeutic agents to treat cancer. Due to the herb-drug interactions, the alternations of drug metabolic enzyme and...

    Authors: Dandan Feng, Tao Tang, Rong Fan, Jiekun Luo, Hanjin Cui, Yang Wang and Pingping Gan

    Citation: BMC Complementary and Alternative Medicine 2018 18:345

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  2. Content type: Research article

    Chronic fat-rich diets consumption is increased risk associated with cardiovascular diseases (CVD). Prevention or reduction the progression of cardiac tissue deterioration could benefit in CVD. This study aime...

    Authors: Arunwan Udomkasemsab, Chattraya Ngamlerst, Poom Adisakwattana, Amornrat Aroonnual, Rungsunn Tungtrongchitr and Pattaneeya Prangthip

    Citation: BMC Complementary and Alternative Medicine 2018 18:344

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  3. Content type: Research article

    Erectile dysfunction (ED) is a common complication of diabetes. This study aimed to explore the beneficial effect of Danshen injection on ED in a streptozotocin (STZ)-induced diabetic rat model and the underly...

    Authors: Yong Zhang, Jian Chen, Hua Ji, Zhang-Gang Xiao, Peiqiang Shen and Lin-Hao Xu

    Citation: BMC Complementary and Alternative Medicine 2018 18:343

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  4. Content type: Research article

    Triphala is an Ayurvedic rasayana formulation reputed for its antitumour activities, and chebulinic acid and chebulagic acid, along with other phenolic acids, have been proposed to be responsible for its effects.

    Authors: Min Wang, Yanru Li and Xianda Hu

    Citation: BMC Complementary and Alternative Medicine 2018 18:342

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  5. Content type: Research article

    Patients with rheumatoid arthritis (RA) have a higher risk of coronary heart disease (CHD). Acupuncture, a commonly used treatment for patients with RA, has not been reported to prevent CHD in patients with RA...

    Authors: Mei-Yao Wu, Ming-Cheng Huang, Hou-Hsun Liao, Jen-Huai Chiang, Yu-Chen Lee, Chung-Y Hsu, Mao-Feng Sun and Hung-Rong Yen

    Citation: BMC Complementary and Alternative Medicine 2018 18:341

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  6. Content type: Research article

    Jian-Pi-Yi-Shen Formula (JPYSF), a Chinese herbal decoction with the efficacies of ‘fortify the spleen and tonify the kidney’ and ‘activate blood and resolve stasis’, is effective for the treatment of chronic ...

    Authors: Xinhui Liu, Jianping Chen, Xiaoyan Liu, Dongtao Wang, Ping Zheng, Airong Qi, Tiegang Yi and Shunmin Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:340

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  7. Content type: Research article

    Obese and overweight individuals have greater illness and disease burden, but previous findings from the 2002 National Health Interview Survey (NHIS) suggest that they are no more likely to use complementary h...

    Authors: Dawn M. Upchurch, Linghui Liang and Fuschia M. Sirois

    Citation: BMC Complementary and Alternative Medicine 2018 18:339

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  8. Content type: Research article

    (Trans)-3,7-Dimethyl-2,6-octadien-1-ol, commonly called geraniol (Ge-OH), is an acyclic monoterpene alcohol with well-known anti-inflammatory and antimicrobial properties. Ge-OH is a non-toxic compound classif...

    Authors: Fernando Rizzello, Chiara Ricci, Michela Scandella, Elena Cavazza, Elisabetta Giovanardi, Maria Chiara Valerii, Massimo Campieri, Antonietta Comparone, Luigia De Fazio, Marco Candela, Silvia Turroni and Enzo Spisni

    Citation: BMC Complementary and Alternative Medicine 2018 18:338

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  9. Content type: Research article

    Rheumatoid arthritis (RA) being an incapacitating disease requires early effective intervention. Considering Methotrexate (MTX)- the first line of treatment for RA- intoxicates the liver; therefore, alternativ...

    Authors: Hiba Hasan, Hanan Ismail, Youmna El-Orfali and Ghada Khawaja

    Citation: BMC Complementary and Alternative Medicine 2018 18:337

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  10. Content type: Research article

    Research on the health effects of probiotics continues to grow, but less is known about consumers’ perceptions of probiotic products and their health effects, and the impact of these perceptions on consumption...

    Authors: S. S. Andersen, K. F. Michaelsen, R. P. Laursen and L. Holm

    Citation: BMC Complementary and Alternative Medicine 2018 18:336

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  11. Content type: Research article

    As Complementary and Alternative medicine (CAM) grows in popularity, there is overt recognition for research evidence to inform clinical practice. While various strategies have been trialed to overcome the bar...

    Authors: Yasamin Veziari, Saravana Kumar and Matthew Leach

    Citation: BMC Complementary and Alternative Medicine 2018 18:335

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  12. Content type: Research article

    Involvement of traditional health practitioners (THPs) in the form of collaboration with the formal health care system is suggested to improve the pathways to mental health care in Kenya, yet understanding of ...

    Authors: Christine W. Musyimi, Victoria N. Mutiso, Lianne Loeffen, Anja Krumeich and David M. Ndetei

    Citation: BMC Complementary and Alternative Medicine 2018 18:334

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  13. Content type: Research article

    Herbal medicines in pregnancy are increasingly used worldwide with prevalence of up to 67%. Although this popularity is mainly because of the common belief that these medicines are safe, recent reports suggest...

    Authors: Mansoor Ahmed, Jung Hye Hwang, Mohammad Ashraful Hasan and Dongwoon Han

    Citation: BMC Complementary and Alternative Medicine 2018 18:333

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  14. Content type: Research article

    The fruit of Elaeagnus umbellata has high medicinal values and is an excellent source of phytochemicals. This study was aimed to evaluate the antioxidant, enzyme inhibitory and antidiabetic potential of Elaeagnus...

    Authors: Nausheen Nazir, Muhammad Zahoor, Mohammad Nisar, Imran Khan, Nasiara Karim, Heba Abdel-Halim and Akhtar Ali

    Citation: BMC Complementary and Alternative Medicine 2018 18:332

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  15. Content type: Research article

    The placenta is a reservoir enriched with growth factors, hormones, cytokines and minerals. While several beneficial effects of placenta extracts on wound healing, anti-aging and anti-inflammatory responses ha...

    Authors: Jae Hyeok Heo, Yoonki Heo, Hee Jung Lee, Minjee Kim and Ha Youn Shin

    Citation: BMC Complementary and Alternative Medicine 2018 18:331

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  16. Content type: Research article

    Baicalin is a flavonoid compound that exerts specific pharmacological effect in attenuating the proliferation, migration, and apoptotic resistance of hypoxia-induced pulmonary artery smooth muscle cells (PASMC...

    Authors: Xiaoying Huang, Wei Mao, Ting Zhang, Meibin Wang, Xuetao Wang, Yaozhe Li, Lin Zhang, Dan Yao, Xueding Cai and Liangxing Wang

    Citation: BMC Complementary and Alternative Medicine 2018 18:330

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  17. Content type: Research article

    Little is studied about complications related to probiotic ingestion. This study proposes to present a synthesis and critical evaluation of the reports and series of cases on the infectious complications relat...

    Authors: Rafael Lessa Costa, José Moreira, Andrea Lorenzo and Cristiane C. Lamas

    Citation: BMC Complementary and Alternative Medicine 2018 18:329

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  18. Content type: Research article

    Celastrus orbiculatus (Celastraceae) are used as traditional Chinese medicine to treat inflammation and cancer. This study aims to evaluate the effect of Celastrus orbiculatus extract (COE) on the apoptosis in hu...

    Authors: Yayun Qian, Ting Yang, Xueyu Zhao, Yan Yan, Wenyuan Li, Chuanci Fang, Jingjing Hou, Li Tao and Yanqing Liu

    Citation: BMC Complementary and Alternative Medicine 2018 18:328

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  19. Content type: Research article

    Soil transmitted helminths (STHs) are among the world’s neglected tropical diseases. Morbidity due to STHs is greatest in school-age children who typically have the highest burden of infection. In 2001, WHO pa...

    Authors: M. Kugo, L. Keter, A. Maiyo, J. Kinyua, P. Ndemwa, G. Maina, P. Otieno and E. M. Songok

    Citation: BMC Complementary and Alternative Medicine 2018 18:327

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  20. Content type: Research article

    Cordyceps sinensis has been used for centuries in China as one of the most valued herbal medicine and tonic food. Paecilomyces hepiali, a fungal strain isolated from natural C. sinensis, has been used widely as a...

    Authors: Mei Ge, Rui Guo, Hai-xia Lou and Wen Zhang

    Citation: BMC Complementary and Alternative Medicine 2018 18:326

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  21. Content type: Research article

    Identification of novel sources for developing new antibiotics is imperative with the emergence of antibiotic resistant bacteria. The fruits of Terminalia bellirica (Gaertn) Roxb., widely used in traditional medi...

    Authors: M. Priyanga Jayamal Dharmaratne, Amirthasingam Manoraj, Vasanthi Thevanesam, Asela Ekanayake, Nimal Savitri Kumar, Veranja Liyanapathirana, Eranga Abeyratne and B. M. Ratnayake Bandara

    Citation: BMC Complementary and Alternative Medicine 2018 18:325

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  22. Content type: Research article

    This study assessed the effects of propolis alone or combined with insulin on maternal status, pregnancy outcomes and placental oxidative stress in streptozotocin-induced diabetic rats.

    Authors: Umar Zayyanu Usman, Ainul Bahiyah Abu Bakar and Mahaneem Mohamed

    Citation: BMC Complementary and Alternative Medicine 2018 18:324

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  23. Content type: Research article

    Weight reduction frequently occurs in patients receiving vagus nerve stimulation (VNS) therapy. Therefore, we hypothesized that during dietary intervention for weight loss, auricular electric stimulation (AES)...

    Authors: Szu-Han Chen, Hsiao-Chien Chen, Ching-Liang Hsieh and Pei-Min Chao

    Citation: BMC Complementary and Alternative Medicine 2018 18:323

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  24. Content type: Research article

    Human infection by pathogenic Salmonella bacteria can be acquired by consuming of undercooked meat products and eggs. Antimicrobial resistance against antibiotics used in medicine is also a major concern. To help...

    Authors: Sung Phil Kim, Sang Jong Lee, Seok Hyun Nam and Mendel Friedman

    Citation: BMC Complementary and Alternative Medicine 2018 18:322

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  25. Content type: Research article

    Eugenol is a natural phenolic compound and possesses anticancer and antibacterial activities. Breast cancer is a major global health problem, and most of the chemotherapeutic agents are highly toxic with long-...

    Authors: Mashan L. Abdullah, Mohamed M. Hafez, Ali Al-Hoshani and Othman Al-Shabanah

    Citation: BMC Complementary and Alternative Medicine 2018 18:321

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  26. Content type: Research article

    Carica papaya leaf juice (CPLJ) was well known for its thrombocytosis activity in rodents and dengue patients. However, the effect of CPLJ treatment on other parameters that could contribute to dengue pathogenesi...

    Authors: Mohd Ridzuan Mohd Abd Razak, Norazlan Mohmad Misnan, Nur Hana Md Jelas, Nor Azrina Norahmad, Amirrudin Muhammad, Tiffiny Chau Dee Ho, Bazilah Jusoh, Umi Rubiah Sastu, Murizal Zainol, Mohd Isa Wasiman, Hussin Muhammad, Ravindran Thayan and Ami Fazlin Syed Mohamed

    Citation: BMC Complementary and Alternative Medicine 2018 18:320

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  27. Content type: Research article

    Pancreatic cancer is one of the most aggressive human malignancies. The development of a novel drug to treat pancreatic cancer is imperative, and it is thought that complementary and alternative medicine (CAM)...

    Authors: Yoshihisa Matsushita, Yoshiyuki Furutani, Rumiko Matsuoka and Toru Furukawa

    Citation: BMC Complementary and Alternative Medicine 2018 18:319

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  28. Content type: Correction

    Authors: Sihle Ephraim Mabhida, Rabia Johnson, Musawenkosi Ndlovu, Nonhlakanipho Felicia Sangweni, Johan Louw, Andrew Opoku and Rebamang Anthony Mosa

    Citation: BMC Complementary and Alternative Medicine 2018 18:318

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    The original article was published in BMC Complementary and Alternative Medicine 2018 18:265

  29. Content type: Research article

    Autophagy occurs in cells that undergoing nutrient deprivation. Glycolysis rapidly supplies energy for the proliferation of cancer cells. Cardamonin inhibits proliferation and enhances autophagy by mTORC1 supp...

    Authors: Daohua Shi, Di Zhao, Peiguang Niu, Yanting Zhu, Jintuo Zhou and Huajiao Chen

    Citation: BMC Complementary and Alternative Medicine 2018 18:317

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  30. Content type: Research article

    Few studies have investigated patient and provider expectations of chiropractic care, particularly in multidisciplinary settings. This qualitative study explored stakeholder expectations of adding a chiropract...

    Authors: Zacariah K. Shannon, Stacie A. Salsbury, Donna Gosselin and Robert D. Vining

    Citation: BMC Complementary and Alternative Medicine 2018 18:316

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  31. Content type: Research article

    Compounds having both anticancer and antimicrobial activity have promising therapeutic potential due to their selective cytotoxicity and their potential to reduce the occurrence of bacterial and fungal infecti...

    Authors: Oluwagbemiga Sewanu Soyingbe, Nkoana Ishmael Mongalo and Tshepiso Jan Makhafola

    Citation: BMC Complementary and Alternative Medicine 2018 18:315

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  32. Content type: Research article

    Replicative senescence of human diploid fibroblasts (HDFs) has been used as a model to study mechanisms of cellular aging. Gamma-tocotrienol (γT3) is one of the members of vitamin E family which has been shown...

    Authors: Jen-Kit Tan, Faizul Jaafar and Suzana Makpol

    Citation: BMC Complementary and Alternative Medicine 2018 18:314

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  33. Content type: Research article

    Tuberculosis (TB) is one of the world’s major communicable infectious diseases, and it still imposes a great health burden in developing countries. The development of drug-resistant TB during the treatment inc...

    Authors: Su-Tso Yang, Yi-Rong Lin, Mei-Yao Wu, Jen-Huai Chiang, Pei-Shan Yang, Te-Chun Hsia and Hung-Rong Yen

    Citation: BMC Complementary and Alternative Medicine 2018 18:313

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  34. Content type: Research article

    Sagunja-tang (SGT) is widely used in traditional herbal medicine to treat immune system and gastrointestinal disorders and reportedly has protective effects against inflammation, cancer, and osteoporosis. In t...

    Authors: Nam-Hui Yim, Min Jung Gu, Hee Ra Park, Youn-Hwan Hwang and Jin Yeul Ma

    Citation: BMC Complementary and Alternative Medicine 2018 18:312

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  35. Content type: Research article

    Neural Therapy (NT) is a common complementary treatment approach using injections with short-acting local anesthetics to treat pain and chronic diseases. However, little is known about the underlying mechanism...

    Authors: Heidemarie Haller, Felix J. Saha, Barbara Ebner, Anna Kowoll, Dennis Anheyer, Gustav Dobos, Bettina Berger and Kyung-Eun Choi

    Citation: BMC Complementary and Alternative Medicine 2018 18:311

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  36. Content type: Research article

    Many studies on transcutaneous electrical nerve stimulation (TENS) had been undertaken to explore its pain relieving efficiency on several medicals/surgical conditions but none, specifically, had been carried ...

    Authors: Uchenna Prosper Okonkwo, Sam Chidi Ibeneme, Ebere Yvonne Ihegihu, Afamefuna Victor Egwuonwu, Ikechukwu Charles Ezema, Adesina Fatai Maruf, Emmanuel Chiebuka Okoye, Olanrewaju Peter Ibikunle and Antoninus Obinna Ezeukwu

    Citation: BMC Complementary and Alternative Medicine 2018 18:310

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    The Correction to this article has been published in BMC Complementary and Alternative Medicine 2019 19:12

  37. Content type: Research article

    Although the physical and mental enhancement effect of essential oils have been proved, the beneficial effect of essential oil in central fatigue remains unclear. In this study, we extracted essential oils fro...

    Authors: Chenxia Han, Feng Li, Simin Tian, Yan Liu, Huai Xiao, Xiumei Wu, Weiyue Zhang, Wei Zhang and Meng Mao

    Citation: BMC Complementary and Alternative Medicine 2018 18:309

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  38. Content type: Study protocol

    Research has almost exclusively focused on the neck in order to explain the mechanisms of persistent pain after motor vehicle collisions (MVC). However, studies have shown that low back pain after MVC is as co...

    Authors: Tonny Elmose Andersen, Hanne Ellegaard, Berit Schiøttz-Christensen and Claus Manniche

    Citation: BMC Complementary and Alternative Medicine 2018 18:308

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  39. Content type: Research article

    The phytochemical constituents and biological activities of Rosa rugosa Thunb. var. plena Regal flower cell sap (RFCS) were investigated.

    Authors: Guixing Ren, Peng Xue, Xiaoyan Sun and Gang Zhao

    Citation: BMC Complementary and Alternative Medicine 2018 18:307

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  40. Content type: Study protocol

    Obesity is characterized by increased fat mass and is associated with the development of insulin resistance syndrome (IRS), usually known as metabolic syndrome. The alteration of the intestinal microbiota comp...

    Authors: Carmen Tenorio-Jiménez, María José Martínez-Ramírez, Mercedes Tercero-Lozano, Carmen Arraiza-Irigoyen, Isabel Del Castillo-Codes, Josune Olza, Julio Plaza-Díaz, Luis Fontana, Jairo H. Migueles, Mónica Olivares, Ángel Gil and Carolina Gomez-Llorente

    Citation: BMC Complementary and Alternative Medicine 2018 18:306

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  41. Content type: Research article

    Croton species (Euphorbiaceae) are distributed in different parts of the world, and are used in traditional medicine to treat various ailments including cancer, inflammation, parasitic infections and oxidative st...

    Authors: Emmanuel Mfotie Njoya, Jacobus N. Eloff and Lyndy J. McGaw

    Citation: BMC Complementary and Alternative Medicine 2018 18:305

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  42. Content type: Research article

    We have previously reported that ingestion of adenosine (ADN) and adenosine-5′-monophosphate (AMP) improves abnormal glucose metabolism in the stroke-prone spontaneously hypertensive rat model of non-obesity-a...

    Authors: Ardiansyah, Yuto Inagawa, Takuya Koseki, Afifah Zahra Agista, Ikuo Ikeda, Tomoko Goto, Michio Komai and Hitoshi Shirakawa

    Citation: BMC Complementary and Alternative Medicine 2018 18:304

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  43. Content type: Research article

    Epimedium sagittatum (Sieb.et Zucc.) Maxim., Ying-Yang-Huo in Chinese has been used as a traditional Chinese medicine and is deemed to “reinforce the kidney Yang”. Previous studies showed that E. sagittatum could...

    Authors: Ni Yan, Ding-Sheng Wen, Yue-Rui Zhao and Shun-Jun Xu

    Citation: BMC Complementary and Alternative Medicine 2018 18:303

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  44. Content type: Research article

    Vascular dementia is the second most common type of dementia that causes cognitive dysfunction. Acupuncture, an ancient therapy, has been mentioned for the treatment of vascular dementia in previous studies. T...

    Authors: Ze-Yu Zhang, Zhe Liu, Hui-Hui Deng and Qin Chen

    Citation: BMC Complementary and Alternative Medicine 2018 18:302

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  45. Content type: Research article

    Essential oil obtained from rhizomes of the Zingiber zerumbet (L.) Smith (popularly known in Brazil as bitter ginger) is mainly constituted by the biomolecule zerumbone, which exhibit untapped antimicrobial poten...

    Authors: Thiago Moreira da Silva, Carlos Danniel Pinheiro, Patricia Puccinelli Orlandi, Carlos Cleomir Pinheiro and Gemilson Soares Pontes

    Citation: BMC Complementary and Alternative Medicine 2018 18:301

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  46. Content type: Research article

    The interest towards botanicals and plant extracts has strongly risen due to their numerous biological effects and ability to counteract chronic diseases development. Among these effects, chemoprevention which...

    Authors: Monia Lenzi, Veronica Cocchi, Aleksandra Novaković, Maja Karaman, Marijana Sakač, Anamarija Mandić, Milica Pojić, Maria Cristina Barbalace, Cristina Angeloni, Patrizia Hrelia, Marco Malaguti and Silvana Hrelia

    Citation: BMC Complementary and Alternative Medicine 2018 18:300

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  47. Content type: Research article

    Brachychiton rupestris and Brachychiton discolor (Malvaceae) are ornamental trees native to Australia. Some members of Brachychiton and its highly related genus, Sterculia, are employed in traditional medicine fo...

    Authors: Amany A. Thabet, Fadia S. Youssef, Michal Korinek, Fang-Rong Chang, Yang-Chang Wu, Bing-Hung Chen, Mohamed El-Shazly, Abdel Nasser B. Singab and Tsong-Long Hwang

    Citation: BMC Complementary and Alternative Medicine 2018 18:299

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  48. Content type: Research article

    Polycystic Ovary Syndrome (PCOS) is a common female reproductive disorder with multiple manifestations. Weight management is a key therapeutic goal. Acupuncture is a potential adjunctive weight loss treatment ...

    Authors: Carolyn Ee, Caroline Smith, Michael Costello, Freya MacMillan, Lisa Moran, Brandi Baylock and Helena Teede

    Citation: BMC Complementary and Alternative Medicine 2018 18:298

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  49. Content type: Research article

    To investigate the present status of Kampo education, which has still not been elucidated, after the introduction of the new core national curriculum of 2015 into nationwide pharmacy education, in all 74 pharm...

    Authors: Yoshinobu Nakada and Makoto Arai

    Citation: BMC Complementary and Alternative Medicine 2018 18:297

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  50. Content type: Research article

    Oral and pharyngeal cancer is the most common malignant human cancers. Chemotherapy is an effective approach for anti-oral cancer therapy, while the drug tolerance and resistance remain a problem for oral canc...

    Authors: Qihong Li, Jun Wen, Kaitao Yu, Yao Shu, Wulin He, Hongxing Chu, Bin Zhang and Cheng Ge

    Citation: BMC Complementary and Alternative Medicine 2018 18:296

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