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  1. Content type: Research article

    For decades, various cardiovascular symptoms have been relieved by the use of Ya-Hom Navakot, which is a formulation comprising 54 herbal medicines. The Thailand Ministry of Public Health listed Ya-Hom Navakot...

    Authors: Napatara Tirawanchai, Sudarat Supapornhemin, Anchaleekorn Somkasetrin, Bhoom Suktitipat and Sumate Ampawong

    Citation: BMC Complementary and Alternative Medicine 2018 18:258

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  2. Content type: Research article

    Biologically-based complementary medicines (BB-CAM) including herbs and nutritional supplements are frequently taken by breast- and gynecological cancer patients undergoing systemic therapy. The aim of this st...

    Authors: Loisa Drozdoff, Evelyn Klein, Marion Kiechle and Daniela Paepke

    Citation: BMC Complementary and Alternative Medicine 2018 18:259

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  3. Content type: Research article

    Pancreatic cancer is one of the most aggressive and mortal cancers. Although several drugs have been proposed for its treatment, it remains resistant and new alternatives are needed. In this context, plants an...

    Authors: Lamia Mouhid, Marta Gómez de Cedrón, Teodoro Vargas, Elena García-Carrascosa, Nieves Herranz, Mónica García-Risco, Guillermo Reglero, Tiziana Fornari and Ana Ramírez de Molina

    Citation: BMC Complementary and Alternative Medicine 2018 18:254

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  4. Content type: Research article

    The male reproductive system is a sensitive and intricate process that can be distressed following exposure to various toxicants. Therapeutic drugs, especially chemotherapeutics, can also adversely affect male...

    Authors: Mona F. Schaalan, Basma K. Ramadan and Azza H. Abd Elwahab

    Citation: BMC Complementary and Alternative Medicine 2018 18:255

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  5. Content type: Research article

    Mitochondrial dysfunction has been implicated in the pathogenesis of ischemic heart disease, exacerbating cardiomyocytes injury in myocardial infarction (MI). Peroxisome proliferator-activated receptor gamma c...

    Authors: Fanghe Li, Shuwen Guo, Chunguo Wang, Xiaolou Huang, Hui Wang, Xiaobo Tan, Qian Cai, Jiani Wu, Yuqin Zhang, Xi Chen, Wangou Lin and Binyue Zhang

    Citation: BMC Complementary and Alternative Medicine 2018 18:253

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  6. Content type: Research article

    Euphorbia supina (ES) has been widely used in folk medicine owing to its antibacterial, hemostatic, and anti-inflammatory properties. The aim of this study was to evaluate the antioxidant and skin-whitening effec...

    Authors: Sa-Haeng Kang, Yong-Deok Jeon, Ji-Yoon Cha, Sung-Woo Hwang, Hoon-Yeon Lee, Min Park, Bo-Ri Lee, Min-Kyoung Shin, Su-Jeong Kim, Sang-Min Shin, Dae-Ki Kim, Jong-Sik Jin and Young-Mi Lee

    Citation: BMC Complementary and Alternative Medicine 2018 18:256

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  7. Content type: Research article

    The search for new antimicrobials should take into account drug resistance phenomenon. Medicinal plants are known as sources of potent antimicrobial compounds including flavonoids. The objective of this invest...

    Authors: Cyrille Ngoufack Tagousop, Jean-de-Dieu Tamokou, Steve Endeguele Ekom, David Ngnokam and Laurence Voutquenne-Nazabadioko

    Citation: BMC Complementary and Alternative Medicine 2018 18:252

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  8. Content type: Research article

    Seed of mature Croton tiglium Linne, also known as Tiglium seed (TS), has been widely used as a natural product due to its several health beneficial properties including anti-tumor and antifungal activities. Desp...

    Authors: Jun-Won Yun, Euna Kwon, Yun-Soon Kim, Seung-Hyun Kim, Ji-Ran You, Hyoung-Chin Kim, Jin-Sung Park, Jeong-Hwan Che, Sang-Koo Lee, Ja-June Jang, Hyeon Hoe Kim and Byeong-Cheol Kang

    Citation: BMC Complementary and Alternative Medicine 2018 18:251

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  9. Content type: Research article

    Among the different kinds of pollution, air pollution continues to increase globally. East Asia is considered to be significantly affected. As a result, the populations in these regions face serious health iss...

    Authors: Thilina U. Jayawardena, K. K. Asanka Sanjeewa, I. P. Shanura Fernando, Bo Mi Ryu, Min-Cheol Kang, Youngheun Jee, Won Woo Lee and You-Jin Jeon

    Citation: BMC Complementary and Alternative Medicine 2018 18:249

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  10. Content type: Research article

    Angiogenesis is a pathobiological hallmark of gastric cancer. However, rare studies focus on angiogenesis in gastric precancerous lesions (GPL). Weipixiao (WPX), a Chinese herbal preparation, is proved clinica...

    Authors: Jinhao Zeng, Ran Yan, Huafeng Pan, Fengming You, Tiantian Cai, Wei Liu, Chuan Zheng, Ziming Zhao, Daoyin Gong, Longhui Chen and Yi Zhang

    Citation: BMC Complementary and Alternative Medicine 2018 18:250

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  11. Content type: Research article

    The macerate of Sida pilosa aerial parts is used empirically for the treatment of intestinal helminthiasis. Previous studies have shown that Sida pilosa aqueous extract (SpAE) has schistosomicidal, antioxidant, a...

    Authors: Hermine Boukeng Jatsa, Ulrich Membe Femoe, Joseph Njiaza, Daniel Simplice Tombe Tombe, Lohik Nguegan Mbolang, Emilienne Tienga Nkondo, Louis-Albert Tchuem Tchuente, Théophile Dimo and Pierre Kamtchouing

    Citation: BMC Complementary and Alternative Medicine 2018 18:247

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  12. Content type: Research article

    Persistent hepatitis B virus (HBV) infection causes liver cirrhosis and hepatocellular carcinoma and constitutes a major worldwide health problem. Currently, anti-HBV drugs are limited to peginterferon and nuc...

    Authors: Yu-Heng Lai, Cheng-Pu Sun, Hsiu-Chen Huang, Jui-Chieh Chen, Hui-Kang Liu and Cheng Huang

    Citation: BMC Complementary and Alternative Medicine 2018 18:248

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  13. Content type: Research article

    Non-pharmacological therapies and practices are commonly used for both health maintenance and management of chronic disease. Patterns and reasons for use of health practices may identify clinically meaningful ...

    Authors: Melvin T. Donaldson, Melissa A. Polusny, Rich F. MacLehose, Elizabeth S. Goldsmith, Emily M. Hagel Campbell, Lynsey R. Miron, Paul D. Thuras and Erin E. Krebs

    Citation: BMC Complementary and Alternative Medicine 2018 18:246

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  14. Content type: Research article

    Er-Xian decoction (EXD), a formula of Chinese medicine, is often used to treat menopausal syndrome in China. The aim of the present study was to explore the potential cardioprotective mechanism of EXD against ...

    Authors: Zhiguo Zhang, Lihua Xiang, Lanping Zhao, Hong Jiao, Zhen Wang, Yubo Li and Yanjing Chen

    Citation: BMC Complementary and Alternative Medicine 2018 18:245

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  15. Content type: Research article

    A. paniculata is widely known for its medicinal values and is traditionally used to treat a wide range of diseases such as cancer, diabetes, skin infections, influenza, diarrhoea, etc. The phytochemical constitue...

    Authors: Ubaid Rasool, Priya S, Afsana Parveen, Saroj Kumar Sah and Hemalatha S

    Citation: BMC Complementary and Alternative Medicine 2018 18:244

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  16. Content type: Research article

    The first-line agents comprising antihistamines for chronic urticaria, are not completely satisfactory. Tripterygium wilfordii Hook F (TwHF), a Chinese herb, has been developed into several Tripterygium agents an...

    Authors: Liu Liu, Huaibo Zhao, Xiaoying Sun, Qi Zheng, Ying Luo, Yi Ru, Ying Zhang, Xi Chen, Bo Zhu, Chengqian Yin, Bin Li and Xin Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:243

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  17. Content type: Research article

    Rhus verniciflua Stokes is an Asian tree species that is used as a food supplement and traditional medicine in Korea. However, its use is restricted by its potential to cause allergy. Thus, allergen-free R. verni...

    Authors: Seon-Ok Lee, Sung-Ji Kim, Ju-Sung Kim, Hyuk Ji, Eun-Ok Lee and Hyo-Jeong Lee

    Citation: BMC Complementary and Alternative Medicine 2018 18:242

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  18. Content type: Research article

    Mental health issues in children have become a serious public health concern in the U.S. within the past few decades. Emerging evidence suggests that Complementary and Alternative Medicine (CAM) can be benefic...

    Authors: Claudia Wang, John Preisser, Yunro Chung and Kaigang Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:241

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  19. Content type: Research article

    Here, we determined in vitro antioxidant activity, total phenols and flavonoids and evaluated antiproliferative activity of three medicinal plant extracts: Trigonella foenum-graecum (Fenugreek), Cassia acutifolia

    Authors: Bayan Al-Dabbagh, Ismail A. Elhaty, Ala’a Al Hrout, Reem Al Sakkaf, Raafat El-Awady, S. Salman Ashraf and Amr Amin

    Citation: BMC Complementary and Alternative Medicine 2018 18:240

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  20. Content type: Research article

    Inflammation has been found to be associated with many neurodegenerative diseases, including Parkinson’s and dementia. Attenuation of microglia-induced inflammation is a strategy that impedes the progression o...

    Authors: Ming-Yii Huang, Chia-En Tu, Shu-Chi Wang, Yung-Li Hung, Chia-Cheng Su, Shih-Hua Fang, Chi-Shuo Chen, Po-Len Liu, Wei-Chung Cheng, Yu-Wei Huang and Chia-Yang Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:221

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  21. Content type: Research article

    Alcohol is consumed almost worldwide and is the most widely used recreational drug in the world. Harmful use of alcohol is known to cause a large disease-, social- and economic burden on society. Only a few st...

    Authors: Kristina Sivertsen, Marko Lukic and Agnete E. Kristoffersen

    Citation: BMC Complementary and Alternative Medicine 2018 18:239

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  22. Content type: Research article

    In Korea, there are two types of medical doctors: one practises conventional medicine (hereafter called a physician), and the other practises traditional medicine (hereafter called a Korean medical doctor). Th...

    Authors: Ju Ah Lee, Yui Sasaki, Ichiro Arai, Ho-Yeon Go, Sunju Park, Keiko Yukawa, Yun Kung Nam, Seong-Gyu Ko, Yoshiharu Motoo, Kiichiro Tsutani and Myeong Soo Lee

    Citation: BMC Complementary and Alternative Medicine 2018 18:238

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  23. Content type: Research article

    Cancers and microbial infections are still a major health problem, therefore research on new anticancer and antimicrobial agents ought to be continued. Natural products including essential oils from medicinal ...

    Authors: Ramzi A. Mothana, Jamal M. Khaled, Omar M. Noman, Ashok Kumar, Mohamed F. Alajmi, Adnan J. Al-Rehaily and Mine Kurkcuoglu

    Citation: BMC Complementary and Alternative Medicine 2018 18:237

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  24. Content type: Research article

    Feifukang (FFK) is a traditional Chinese medicine composed of herbs that protect lung function. However, difficulty arises regarding the clinical application of FFK due to the complex mechanism of Chinese medi...

    Authors: Hongbo Li, Zhenkai Wang, Jie Zhang, Youlei Wang, Chen Yu, Jinjin Zhang, Xiaodong Song and Changjun Lv

    Citation: BMC Complementary and Alternative Medicine 2018 18:234

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  25. Content type: Research article

    Sotetsuflavone is isolated from Cycas revoluta Thunb., which has biological activity against tumors. However, the anti-proliferative effects of sotetsuflavone on A549 cells and its mechanism are not fully elucida...

    Authors: Shaohui Wang, Yanlan Hu, Yu Yan, Zhekang Cheng and Tongxiang Liu

    Citation: BMC Complementary and Alternative Medicine 2018 18:235

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  26. Content type: Research article

    Cancer-related anorexia remains one of the most prevalent and troublesome clinical problems experienced by patients with cancer during and after therapy. To ensure high-quality care, systematic reviews (SRs) a...

    Authors: Fangyuan Zhang, Aomei Shen, Yinghui Jin and Wanmin Qiang

    Citation: BMC Complementary and Alternative Medicine 2018 18:236

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  27. Content type: Research article

    Bombax ceiba is used traditionally to treat bone disorders, rheumatism, and joint pain. The aim of the study is to carry out osteogenic activity in-vitro and anti-osteoporotic activity in-vivo of stem bark of B. ...

    Authors: Shashi Chauhan, Aditi Sharma, Navneet Kumar Upadhyay, Gajender Singh, Uma Ranjan Lal and Rohit Goyal

    Citation: BMC Complementary and Alternative Medicine 2018 18:233

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  28. Content type: Research article

    Dendritic cells (DCs) are unique antigen presenting cells (APC) which play a pivotal role in immunotherapy and induction of an effective immune response against tumors. In the present study, 80% ethanol extrac...

    Authors: Shimaa Ibrahim Abdelmenym Mohamed, Ibrahim Jantan, Mohd Azlan Nafiah, Mohamed Ali Seyed and Kok Meng Chan

    Citation: BMC Complementary and Alternative Medicine 2018 18:232

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  29. Content type: Research article

    Lagerstroemia speciosa (L.) Pers. (Family: Lythraceae) is used in traditional medicine in the treatment of diarrhea, diabetes and other diseases. The study was performed to conduct antioxidant, cytotoxic, thrombo...

    Authors: Tasnuva Sharmin, Md. Shahidur Rahman and Habiba Mohammadi

    Citation: BMC Complementary and Alternative Medicine 2018 18:231

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  30. Content type: Research article

    Astragalus membranaceus (Fisch.) Bunge is one of the most widely used traditional Chinese herbal medicines. It is used as immune stimulant, tonic, antioxidant, hepatoprotectant, diuretic, antidiabetic, anticancer...

    Authors: Yizhe Cui, Qiuju Wang, Rui Sun, Li Guo, Mengzhu Wang, Junfeng Jia, Chuang Xu and Rui Wu

    Citation: BMC Complementary and Alternative Medicine 2018 18:230

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  31. Content type: Research article

    The prevalence of complementary medicine use in pregnancy and lactation has been increasingly noted internationally. This systematic review aimed to determine the complementary medicine products (CMPs) used in...

    Authors: Larisa Ariadne Justine Barnes, Lesley Barclay, Kirsten McCaffery and Parisa Aslani

    Citation: BMC Complementary and Alternative Medicine 2018 18:229

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  32. Content type: Research article

    Neonatal jaundice affects at least 481,000 newborns every year. Phototherapy is recommended but it’s effects are limited and adverse reactions can occur. In China, phototherapy combined with Yinzhihuang oral l...

    Authors: Ruo-han Wu, Shuo Feng, Mei Han, Patrina Caldwell, Shi-gang Liu, Jing Zhang and Jian-ping Liu

    Citation: BMC Complementary and Alternative Medicine 2018 18:228

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  33. Content type: Research article

    Although Galanthus nivalis L. (snowdrop) is known for the galanthamine content, used in the treatment of Alzheimer disease, the polyphenolic compounds of Amaryllidaceae species are less studied. Proper understand...

    Authors: Daniela Benedec, Ilioara Oniga, Daniela Hanganu, Ana Maria Gheldiu, Cristina Pușcaș, Radu Silaghi-Dumitrescu, Mihaela Duma, Brîndușa Tiperciuc, Rodica Vârban and Laurian Vlase

    Citation: BMC Complementary and Alternative Medicine 2018 18:226

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  34. Content type: Research article

    The increasing number of multidrug-resistant bacteria and the fact of antibiotic resistance is leading to a continuous need for discovering alternative treatments against infections, e.g. in the case of respir...

    Authors: Kamilla Ács, Viktória L. Balázs, Béla Kocsis, Tímea Bencsik, Andrea Böszörményi and Györgyi Horváth

    Citation: BMC Complementary and Alternative Medicine 2018 18:227

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  35. Content type: Research article

    Chagas Disease caused by Trypanosoma cruzi infection, is one of the most important neglected tropical diseases (NTD), without an effective therapy for the successful parasite eradication or for the blocking of th...

    Authors: Érika Marcela Moreno, Sandra Milena Leal, Elena E. Stashenko and Liliana Torcoroma García

    Citation: BMC Complementary and Alternative Medicine 2018 18:225

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  36. Content type: Research article

    Phyllanthus amarus has been used widely in various traditional medicines to treat swelling, sores, jaundice, inflammatory diseases, kidney disorders, diabetes and viral hepatitis, while its pharmacological and bi...

    Authors: Hemavathy Harikrishnan, Ibrahim Jantan, Md. Areeful Haque and Endang Kumolosasi

    Citation: BMC Complementary and Alternative Medicine 2018 18:224

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  37. Content type: Research article

    Streblus asper is a well-known plant native to Southeast Asia. Different parts of the plant have been traditionally used for various medicinal purposes. However, there is very little scientific evidence reporting...

    Authors: Anchalee Prasansuklab, Atsadang Theerasri, Matthew Payne, Alison T. Ung and Tewin Tencomnao

    Citation: BMC Complementary and Alternative Medicine 2018 18:223

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  38. Content type: Research article

    Medicinal plants represent a source of new drugs for the prevention and treatment of infectious diseases. Dendropanax morbifera Léveille is an economically and medicinally important subtropical tree that has vari...

    Authors: Biruk Tesfaye Birhanu, Jin-Yoon Kim, Md. Akil Hossain, Jae-Won Choi, Sam-Pin Lee and Seung-Chun Park

    Citation: BMC Complementary and Alternative Medicine 2018 18:222

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  39. Content type: Research article

    Endothelial cells are sensitive to changes in both blood components and mechanical stimuli. Endothelial cells may undergo phenotypic changes, such as changes in adhesion protein expression, under different she...

    Authors: Ming Zhang, Jie Sun, Beidong Chen, Yanyang Zhao, Huan Gong, Yun You and Ruomei Qi

    Citation: BMC Complementary and Alternative Medicine 2018 18:220

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  40. Content type: Research article

    Propolis is a natural substance produced by bees and is known to have antimicrobial activity. Our aim was to evaluate the antimicrobial effect of micellar nanocomposites loaded with an ethyl acetate extract of...

    Authors: Isabel Cristina Celerino de Moraes Porto, Dayse Chaves Cardoso de Almeida, Gabriela Vasconcelos Calheiros de Oliveira Costa, Tayná Stéphanie Sampaio Donato, Letícia Moreira Nunes, Ticiano Gomes do Nascimento, José Marcos dos Santos Oliveira, Carolina Batista da Silva, Natanael Barbosa dos Santos, Maria Luísa de Alencar e Silva Leite, Irinaldo Diniz Basílio-Júnior, Camila Braga Dornelas, Pierre Barnabé Escodro, Eduardo Jorge da Silva Fonseca and Regianne Umeko Kamiya

    Citation: BMC Complementary and Alternative Medicine 2018 18:219

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  41. Content type: Research article

    The polysaccharide component of Angelica gigas induces immuno-stimulatory effects on innate immune cells. However, it is unclear whether A. gigas’ adjuvant activity on the immune system can elicit anti-cancer res...

    Authors: Seo Hyun Kim, Sung Won Lee, Hyun Jung Park, Sang Hee Lee, Won Kyun Im, Young Dong Kim, Kyung Hee Kim, Sang Jae Park, Seokmann Hong and Sung Ho Jeon

    Citation: BMC Complementary and Alternative Medicine 2018 18:218

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  42. Content type: Research article

    Histamine is a well-known mediator involved in skin allergic responses through up-regulation of pro-inflammatory cytokines. Antihistamines remain the mainstay of allergy treatment, but they were found limited ...

    Authors: Nurul Atika Razali, Nur Amiza Nazarudin, Kok Song Lai, Faridah Abas and Syahida Ahmad

    Citation: BMC Complementary and Alternative Medicine 2018 18:217

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  43. Content type: Research article

    Ipomoea batatas L. Lam. is a functional food and belongs to family Convolvulaceae. It is used as an antiinflammatory, aphrodisiac, antiasthmatic, anticonvalescent, antitumor, antanemic and antidiabetic agent by l...

    Authors: Muhammad Majid, Bakht Nasir, Syeda Saniya Zahra, Muhammad Rashid Khan, Bushra Mirza and Ihsan-ul Haq

    Citation: BMC Complementary and Alternative Medicine 2018 18:216

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  44. Content type: Research article

    Identifying ornamental plants as new natural antioxidant and antimicrobial sources is always of great importance for the ornamental and horticultural industries.

    Authors: Hosam O. Elansary, Samir A. M. Abdelgaleil, Eman A. Mahmoud, Kowiyou Yessoufou, Khalid Elhindi and Salah El-Hendawy

    Citation: BMC Complementary and Alternative Medicine 2018 18:214

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  45. Content type: Research article

    Jawoongo is an herbal mixture used in traditional medicine to treat skin diseases. This study aimed to investigate whether Jawoongo ameliorates Atopic dermatitis (AD)-like pathology in mice and to understand i...

    Authors: Jin Mo Ku, Se Hyang Hong, Soon Re Kim, Han-Seok Choi, Hyo In Kim, Dong Uk Kim, So Mi Oh, Hye Sook Seo, Tai Young Kim, Yong Cheol Shin, Chunhoo Cheon and Seong-Gyu Ko

    Citation: BMC Complementary and Alternative Medicine 2018 18:215

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  46. Content type: Research article

    Plant derived medicines show significant contributions to mankind in treating infections of pathogenic bacteria. Recently plants are used in pharmaceutical industries for novel drug preparations because to ens...

    Authors: Sunanda Burman, Kuntal Bhattacharya, Devaleena Mukherjee and Goutam Chandra

    Citation: BMC Complementary and Alternative Medicine 2018 18:213

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  47. Content type: Research article

    Exposure to carbon black nanoparticles (CBNPs), a well-known industrial production, promotes pulmonary toxicity through inflammation and oxidative stress. Recent studies show that some polyphenols exert their ...

    Authors: Hung-Te Hsu, Yu-Ting Tseng, Wen-Jhe Wong, Chi-Ming Liu and Yi-Ching Lo

    Citation: BMC Complementary and Alternative Medicine 2018 18:211

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  48. Content type: Research article

    Liuweiwuling tablets (LWWL) are an herbal product that exerts remarkable effects on liver protection and aminotransferase levels, and they have been approved by the Chinese State Food and Drug Administration (...

    Authors: Huimin Liu, Zhenfang Zhang, Huangwanyin Hu, Congen Zhang, Ming Niu, Ruishen Li, Jiabo Wang, Zhaofang Bai and Xiaohe Xiao

    Citation: BMC Complementary and Alternative Medicine 2018 18:212

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  49. Content type: Research article

    In China, demands for disease prevention and health care and the prevalence of chronic non-communicable diseases have increased. TCM and general hospitals are increasingly utilizing TCM strategies for chronic ...

    Authors: Xiaoqing Fan, Fanli Meng, Dahui Wang, Qing Guo, Zhuoyu Ji, Lei Yang and Atsushi Ogihara

    Citation: BMC Complementary and Alternative Medicine 2018 18:209

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