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Table 1 Changes in biochemical markers of wound healing at late inflammatory phase (day 4) and wound repair phase (day 10) during healing

From: Selenium added unripe carica papaya pulp extracts enhance wound repair through TGF-β1 and VEGF-a signalling pathway

Group

Day

Total protein

Hydroxyproline

Hexuronic acid

Hexosamine

  

(mg/g tissue)

(μg/mg tissue)

(mg/g tissue)

(mg/g tissue)

NC

4

19.43 ± 0.94

8.47 ± 1.50

20.71 ± 4.36

12.54 ± 4.53

10

51.52 ± 1.55

25.35 ± 1.04

5.82 ± 1.28

4.59 ± 1.57

PC

4

36.68 ± 1.06* *** ****

14.24 ± 1.31

49.39 ± 4.71*

28.41 ± 4.07

10

80.42 ± 0.86* *** ****

40.62 ± 0.60* ****

8.65 ± 2.03

10.55 ± 2.91

PE

4

23.47 ± 1.38

12.06 ± 2.97

53.41 ± 6.21* ****

30.31 ± 6.11

10

61.70 ± 1.37* ****

37.74 ± 1.24* ****

8.70 ± 1.70

10.12 ± 2.78

WE

4

23.18 ± 2.03

11.41 ± 2.70

25.45 ± 5.32

14.86 ± 3.60

10

53.43 ± 1.50

27.25 ± 1.03*

6.30 ± 1.83

5.62 ± 1.45

PES

4

39.47 ± 2.05* *** ****

20.07 ± 3.19*

60.84 ± 6.08* ****

35.23 ± 4.95*

10

95.14 ± 1.15* ** *** ****

55.15 ± 1.06* ** *** ****

18.12 ± 3.32*

18.21 ± 3.03* ****

WES

4

37.94 ± 1.15* *** ****

19.80 ± 2.51*

53.81 ± 7.36* ****

28.34 ± 3.87

10

85.35 ± 2.11* *** ****

52.61 ± 1.02* ** *** ****

16.62 ± 4.88

16.51 ± 4.08

PEZ

4

21.31 ± 1.41

8.97 ± 1.93

26.47 ± 3.32

18.90 ± 3.21

10

56.04 ± 1.48

30.52 ± 1.23*

6.85 ± 1.92

6.66 ± 2.12

WEZ

4

20.57 ± 1.60

10.83 ± 1.31

30.59 ± 6.27

20.06 ± 4.16

10

56.97 ± 1.70

31.32 ± 1.34*

5.24 ± 1.64

6.53 ± 2.25

  1. Values are expressed as mean ± SEM (n = 5). *, **, *** and **** represent significantly increased (p < 0.05) wound content as compared to NC, PC, PE and WE respectively on the respective days