Aphrodisiac agents are used to modify the impaired sexual functions of human beings. These agents have been used since a pretty long time and there are enough evidence showing their use by the ancient Greek and Arab physicians eg. Hippocrat (460 B.C.), Dioscorides (70 A.D.), Raazi (926 A.D.), Ibn-e-Sina (1038 A.D.) etc. The availability of the large number of sexual function improving drugs in the traditional Unani System of Medicine is a unique and distinctive feature of this system. Besides having many specific drugs for enhancing sexual functions, there are certain most commonly used spices like Myristica fragrans Houtt, (Nutmeg) Syzygium aromatium (L) Merr. & Perry.(clove) and Piper nigrum. Linn. (black paper) etc. which are empirically used as promising aphrodisiacs in traditional medicine practice in cases of sexual debility or depressed desire .
Nutmeg is dried kernel of broadly ovoid seed of Myristica fragrans Houtt (Family: Myristicaceae) a bushy evergreen tree about 10–20 m. in height indigenous to India, Indonesia and Srilanka [2–4]. It has been mentioned in ethnomedical literature as aphrodisiac [5, 6], stomachic, carminative , tonic  and nervous stimulant . It is useful in paralysis  and increase blood circulation [11, 12]. Nutmeg contains 30–40% fats and by expression it yields a product known as nutmeg butter, this consists of 12.5% of volatile oil. The volatile oil contains pinene and camphene (80%), eugenol and myristicin, etc .
Clove is the dried bud of Syzygium aromaticum Merr. & Perry. (Family: Myrtaceae) an evergreen tree 10–20 m. in height indigenous to India, Indonesia, Zanzibar, Mauritius and Ceylon. Clove are reported as aphrodisiac [14, 15], stomachic [16, 17], carminative, nervous stimulant  and tonic . It contains volatile oil (14–21%), Tannin (10–13%), phenol, sesquetrepen ester and alcohol etc .
Nutmeg and Clove have not been evaluated in depth for their pharmacological properties, inspite of their traditional use in numerous medical conditions. The traditional use indicates that Nutmeg and Clove are having several pharmacological properties. It has been reported that several unani formulations containing Nutmeg and Clove were used as aphrodisiacs . However, claim of their efficacy is yet to be scientifically substantiated. In the present study the effects of 50% ethanolic extracts of Nutmeg and Clove were evaluated experimentally and compared with the standard drug Penegra (Sildenafil citrate).