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  1. Research article

    An interpretive review of consensus statements on clinical guideline development and their application in the field of traditional and complementary medicine

    Despite ongoing consumer demand and an emerging scientific evidence-base for traditional and complementary medicine (T&CM), there remains a paucity of reliable information in standard clinical guidelines about...

    Jennifer Hunter, Matthew Leach, Lesley Braun and Alan Bensoussan

    BMC Complementary and Alternative Medicine 2017 17:116

    Published on: 17 February 2017

  2. Research article

    UP601, a standardized botanical composition composed of Morus alba, Yerba mate and Magnolia officinalis for weight loss

    The prevalence of obesity is surging in an alarming rate all over the world. Pharmaceutical drugs are considered potential adjunctive therapy to lifestyle modification. However, for most, besides being too exp...

    Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Eu-Jin Hyun, Hyun-Jin Kim, Jeong-Bum Nam, Mi-Ran Kim and Qi Jia

    BMC Complementary and Alternative Medicine 2017 17:114

    Published on: 16 February 2017

  3. Research article

    Use of ethanol extracts of Terminalia chebula to prevent periodontal disease induced by dental plaque bacteria

    The fruit of the Terminalia chebula tree has been widely used for the treatment of various disorders. Its anti-diabetic, anti-mutagenic, anti-oxidant, anti-bacterial, anti-fungal, and anti-viral effects have been...

    Jongsung Lee, Youn Hwa Nho, Seok Kyun Yun and Young Sun Hwang

    BMC Complementary and Alternative Medicine 2017 17:113

    Published on: 16 February 2017

  4. Research article

    BreastDefend enhances effect of tamoxifen in estrogen receptor-positive human breast cancer in vitro and in vivo

    Tamoxifen (TAM) has been widely used for the treatment of estrogen receptor (ER)-positive breast cancer and its combination with other therapies is being actively investigated as a way to increase efficacy and...

    Shujie Cheng, Victor Castillo, Matt Welty, Mark Alvarado, Isaac Eliaz, Constance J. Temm, George E. Sandusky and Daniel Sliva

    BMC Complementary and Alternative Medicine 2017 17:115

    Published on: 16 February 2017

  5. Research article

    Anti-arthritic property of crude extracts of Piptadeniastrum africanum (Mimosaceae) in complete Freund’s adjuvant-induced arthritis in rats

    Rheumatoid arthritis, disease of unknown causes is a rheumatic and autoimmune pathology, recognised for its increasing frequency and its adverse consequences. It is a disease that occurs in most cases between ...

    Marius Mbiantcha, Jabeen Almas, Simjee U. Shabana, Dastagir Nida and Faheem Aisha

    BMC Complementary and Alternative Medicine 2017 17:111

    Published on: 15 February 2017

  6. Research article

    Anti-HSV-2 activity of Terminalia chebula Retz extract and its constituents, chebulagic and chebulinic acids

    Development of new and effective therapeutics for sexually transmitted herpes simplex virus-2 (HSV-2) infection is important from public health perspective. With an aim to identify natural products from medici...

    Ajay Kesharwani, Suja Kizhiyedath Polachira, Reshmi Nair, Aakanksha Agarwal, Nripendra Nath Mishra and Satish Kumar Gupta

    BMC Complementary and Alternative Medicine 2017 17:110

    Published on: 14 February 2017

  7. Research article

    Hair growth-promoting effect of Geranium sibiricum extract in human dermal papilla cells and C57BL/6 mice

    Geranium sibiricum L. has been used as a medicinal plant to treat diarrhea, bacterial infection, and cancer in Bulgaria, Peru, and Korea. However, its hair growth-promoting effect was ...

    William A. Boisvert, Miri Yu, Youngbin Choi, Gi Hee Jeong, Yi-Lin Zhang, Sunghun Cho, Changsun Choi, Sanghyun Lee and Bog-Hieu Lee

    BMC Complementary and Alternative Medicine 2017 17:109

    Published on: 13 February 2017

  8. Research article

    Medication use by middle-aged and older participants of an exercise study: results from the Brain in Motion study

    Over the past 50 years, there has been an increase in the utilization of prescribed, over-the-counter (OTC) medications, and natural health products. Although it is known that medication use is common among ol...

    Tania Pannu, Sarah Sharkey, Grazyna Burek, Daniela Cretu, Michael D. Hill, David B. Hogan and Marc J. Poulin

    BMC Complementary and Alternative Medicine 2017 17:105

    Published on: 10 February 2017

  9. Research article

    Cryptotanshinone enhances the effect of Arsenic trioxide in treating liver cancer cell by inducing apoptosis through downregulating phosphorylated- STAT3 in vitro and in vivo

    Arsenic trioxide (ATO) is approved for treating terminal-stage liver cancer in China. Cryptotanshinone (CT), a STAT3 inhibitor, has exhibited certain anti-tumor potency; however, the use of CT enhanced ATO for...

    Li Shen, Guangshun Zhang, Zhaohuan Lou, Guanhua Xu and Guangji Zhang

    BMC Complementary and Alternative Medicine 2017 17:106

    Published on: 10 February 2017

  10. Research article

    Comparative studies on the multi-component pharmacokinetics of Aristolochiae Fructus and honey-fried Aristolochiae Fructus extracts after oral administration in rats

    Aristolochiae Fructus (AF) and honey-fried Aristolochiae Fructus (HAF) have been used in China for a long time as anti-tussive and expectorant drugs. Few clinical cases have been repor...

    Jinbin Yuan, Gang Ren, Jian Liang, Chong-Zhi Wang, Zhihong Yan, Qun Huang, Jiankang Li, Yang Chen, Yi Tang, Xiaofei Liu and Chun-Su Yuan

    BMC Complementary and Alternative Medicine 2017 17:107

    Published on: 10 February 2017

  11. Research article

    Promotion of HepG2 cell apoptosis by flower of Allium atroviolaceum and the mechanism of action

    Liver cancer is a high incidence and fatal disease, the fifth most frequent cancer worldwide that is usually diagnosed at an advanced stage. The number of deaths from liver cancer has not declined even followi...

    S. Khazaei, R. Abdul Hamid, N. Mohd Esa, V. Ramachandran, Ghomi Tabatabaee F. Aalam, A. Etemad and P. Ismail

    BMC Complementary and Alternative Medicine 2017 17:104

    Published on: 10 February 2017

  12. Research article

    Feasibility study of transfer function model on electrocardiogram change caused by acupuncture

    Acupuncture treatments that regulate the heart are used to treat various clinical disorders and conditions. Although many studies have been conducted to measure quantitatively the effects of acupuncture, thus ...

    Haebeom Lee, Hyunho Kim, Jungkuk Kim, Hwan-Sup Oh, Young-Jae Park and Young-Bae Park

    BMC Complementary and Alternative Medicine 2017 17:101

    Published on: 8 February 2017

  13. Research article

    Study of phytochemical, anti-microbial, anti-oxidant, and anti-cancer properties of Allium wallichii

    There is growing interest in the use of plants for the treatment and prevention of cancer. Medicinal plants are currently being evaluated as source of promising anticancer agents. In this paper, we have invest...

    Jaya Bhandari, BushraTaj Muhammad, Pratiksha Thapa and Bhupal Govinda Shrestha

    BMC Complementary and Alternative Medicine 2017 17:102

    Published on: 8 February 2017

  14. Research article

    Antibacterial and antioxidant properties of crude extract, fractions and compounds from the stem bark of Polyscias fulva Hiern (Araliaceae)

    In our previous work, the dichloromethane-methanol (1:1 v/v) extract, fractions and isolated compounds from Polyscias fulva stem bark showed interesting antifungal activity. As a continuity of that work, this stu...

    Guy Sedar Singor Njateng, Zhizhi Du, Donatien Gatsing, Raymond Simplice Mouokeu, Yaping Liu, Hong-Xia Zang, Jianlong Gu, Xiaodong Luo and Jules-Roger Kuiate

    BMC Complementary and Alternative Medicine 2017 17:99

    Published on: 7 February 2017

  15. Research article

    Anti-influenza virus activity of extracts from the stems of Jatropha multifida Linn. collected in Myanmar

    To contribute to the development of novel anti-influenza drugs, we investigated the anti-influenza activity of crude extracts from 118 medicinal plants collected in Myanmar. We discovered that extract from the...

    Masaki Shoji, So-Yeun Woo, Aki Masuda, Nwet Nwet Win, Hla Ngwe, Etsuhisa Takahashi, Hiroshi Kido, Hiroyuki Morita, Takuya Ito and Takashi Kuzuhara

    BMC Complementary and Alternative Medicine 2017 17:96

    Published on: 7 February 2017

  16. Research article

    Spasmogenic and spasmolytic activity of rind of Punica granatum Linn

    Rind of Punica granatum is traditionally used in treatment of abdominal cramps and various GIT disorders. So far spasmolytic activity of rind of Punica granatum has been reported using in vitro model. However, it...

    Niaz Ali, Ayesha Jamil, Syed Wadood Ali Shah, Ismail Shah and Ghayour Ahmed

    BMC Complementary and Alternative Medicine 2017 17:97

    Published on: 7 February 2017

  17. Research article

    Effects of Angelicae dahuricae Radix on 2, 4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions in mice model

    Atopic dermatitis (AD) is an inflammatory, chronically relapsing, and intensively pruritic skin disease that affect 10–30% of the global population. Angelicae dahuricae Radix (ADR) has been reported to be anti-in...

    Jin Mo Ku, Se Hyang Hong, Hyo In Kim, Hye Sook Seo, Yong Cheol Shin and Seong-Gyu Ko

    BMC Complementary and Alternative Medicine 2017 17:98

    Published on: 7 February 2017

  18. Research article

    A Randomized controlled trial of the effect of yoga and peer support on glycaemic outcomes in women with type 2 diabetes mellitus: a feasibility study

    Type two diabetes is a complex and demanding chronic disease and its impact in a state (Kerala) which leads India in terms of the number of people with Diabetes is profound. Though the male to female ratio amo...

    Aswathy Sreedevi, Unnikrishnan Ambika Gopalakrishnan, Sundaram Karimassery Ramaiyer and Leelamoni Kamalamma

    BMC Complementary and Alternative Medicine 2017 17:100

    Published on: 7 February 2017

  19. Research article

    Chemical constituents and coagulation activity of Agastache rugosa

    In the Chinese traditional medicine, plant of Agastache rugosa (Fisch. & C.A. Mey.) Kuntze (A. rugosa) has been used to treat nausea, vomiting and dispel damp. However, currently, few reports about the chemical c...

    Pengran Cao, Pingyao Xie, Xuebiao Wang, Jinmei Wang, Jinfeng Wei and Wen-yi Kang

    BMC Complementary and Alternative Medicine 2017 17:93

    Published on: 6 February 2017

  20. Research article

    Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats

    Brucea javanica (B. javanica) seeds, also known as “Melada pahit” in Indo-Malay region are traditionally used to treat diabetes. The objective of this study was to determine antidiabet...

    Abdulwali Ablat, Mohammed Farouq Halabi, Jamaludin Mohamad, Muhammad Hafiz Husna Hasnan, Hazrina Hazni, Ser-huy Teh, Jamil A. Shilpi, Zulqarnain Mohamed and Khalijah Awang

    BMC Complementary and Alternative Medicine 2017 17:94

    Published on: 6 February 2017

  21. Research article

    Potential of Zanthoxylum leprieurii as a source of active compounds against drug resistant Mycobacterium tuberculosis

    Tuberculosis (TB) is still a global health problem mainly due to development of resistance and co-infection with the Human immune Virus (HIV). Treatment of multi and extensively drug resistant TB requires use ...

    Lydia Bunalema, Ghislain Wabo Fotso, Paul Waako, John Tabuti and Samuel O. Yeboah

    BMC Complementary and Alternative Medicine 2017 17:89

    Published on: 2 February 2017

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