Fig. 3

The suppression of LPS-induced apoptosis by EGCG. Apoptotic markers were measured at the protein level (A-D) and gene expression (E-H) through ELISA and RT-qPCR methods, respectively. EGCG caused the suppression of cell death induced by LPS through a significant increase in the level of BCL-2 anti-apoptotic factor (A, E) and a decrease in apoptotic mediators including BAX (B, F), CASP-3 (C, G), and CASP-9 (D, H). The lowercase letters presented on the bars describe the result of the statistical analysis, where different letters indicate significant differences between groups; the p-value < 0.05 was considered significant