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Table 3 The statistics of multivariate logistic regression of daily intake and onset of drug-induced interstitial lung disease

From: Analysis of drug-induced interstitial lung disease caused by herbal medicine using the Japanese Adverse Drug Event Report database

 

Estimate (95% CI)

p–value (Prob > ChiSq)

Adjusted reporting odds ratio (95% CI)

Crude reporting odds ratio (95% CI)

Intercept

β10

-22.62 (-52.73 − 7.46)

0.1406

  

Reporting year

β11

0.01 (0.00 − 0.03)

0.1735

1.01 (1.00 − 1.03)

 

Scutellariae radix (SR) daily intake

β12

0.38 (0.30 − 0.46)

< 0.0001*

1.47 (1.36 − 1.59)

1.50 (1.42 − 1.58)

Pinelliae tuber (PT) daily intake

β13

0.05 (0.01 − 0.09)

0.0204*

1.05 (1.01 − 1.10)

1.15 (1.11 − 1.18)

Sex (Male)

β14

0.37 (0.30 − 0.45)

< 0.0001*

1.45 (1.34 − 1.57)

1.55 (1.45 − 1.67)

Age (≥ 60 years)

β15

0.65 (0.55 − 0.75)

< 0.0001*

1.92 (1.74 − 2.11)

1.94 (1.77 − 2.13)

SR daily intake*Age (≥ 60 years)

β16

0.17 (0.10 − 0.25)

< 0.0001*

3.35 (3.12 − 3.60)

 

SR daily intake*PT daily intake

β17

-0.04 (− 0.06 − -0.01)

0.0043*

1.49 (1.46 − 1.53)

 
  1. CI Confidence interbal
  2. * p-value < 0.05