Metabolic profiling of milk thistle different organs using UPLC-TQD-MS/MS coupled to multivariate analysis in relation to their selective antiviral potential

Table 1 Linearity and sensitivity parameters for caffeic acid, malic acid, quercetin, p-coumaryl alcohol, coumarin, lanosterol and linoleic acid used as S. marianum standards

	Standard compounds	Linearity range (mg mL⁻¹)	Slope (b)	Intercept (a)	r	LOD (mg mL⁻¹)	LOQ (mg mL⁻¹)
1	Caffeic acid	0.0125–0.25	32*10⁵	35*10⁷	0.996	0.005	0.0125
2	Malic acid	0.025–0.536	2.87*10⁸	-8.35*10⁹	0.993	0.010	0.025
3	Quercetin	0.02–0.525	20.51*10⁶	-1.07*10⁸	0.995	0.012	0.02
4	Coumarin	0.055–0.625	5170	8.15*10⁸	0.994	0.003	0.0325
5	p-Coumaryl alcohol	0.0325–0.625	41.71*10⁶	-10.39*10⁸	0.997	0.015	0.055
6	Lanosterol	0.0125-0.25	1317.3	84.58*10⁶	0.993	0.005	0.0125
7	Linoleic acid	0.0135–0.255	30.71*10²	14.99*10⁶	0.995	0.003	0.0135

ISSN: 2662-7671