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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Triptolide mitigates the inhibition of osteogenesis induced by TNF-α in human periodontal ligament stem cells via the p-IκBα/NF-κB signaling pathway: an in-vitro study

Fig. 3

Effects of TNF-α and triptolide on ALP activity and mineralized nodule deposition of hPDLSCs. (A) ALP staining under control, TNF-α, TNF-α (20ng/ml) and triptolide (10− 11M) treatment after osteogenic induction for 7 days. (B) ALP activity under control, TNF-α, TNF-α (20ng/ml) and triptolide (10− 11M) treatment for 7 days. (C) Formation of mineralized nodules under control (ab), TNF-α (cd), TNF-α (20ng/ml) and triptolide (10− 11M) (ef) treatment for 21 days. (D) Extracellular matrix mineralisation was assessed at OD562

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