Novel drug therapy of acute hepatic failure induced in rats by a combination of tadalafil and Lepidium sativum

Table 2 summarized the lesion score of the studied groups

Groups Lesions	Control -ve	CCL₄	CCL₄ + LS	CCL₄ + T	CCL₄ + LS + T
Congestion of CV	-	+++	+	+	+
Congestion of portal bl.vs	-	++	+	+	-
Thrombosis of portal bl.vs	-	+	-	-	-
Perivascular fibrosis	-	++	-	-	-
Vacuolar degeneration	-	+++	+	++	-
Mononuclear cell infiltration	-	++	-	-	-

- No lesions, + lesions present in 2–3 sections, ++ lesions present in 4–7 sections, +++ lesions present in 8–10 sections
-CCL₄ (carbon tetrachloride), LS (Lepidium sativum), T (tadalafil)

ISSN: 2662-7671