Table 1 Elevated plus maze behavioral assay

Number of enters in open arms

5 ± 0.79a

1.9 ± 0.33b

2.7 ± 0.3b

1.6 ± 0.18b

5 ± 0.5a

< 0.0001

Time spent in open rms (min)

82.90 ± 11.45a

20.50 ± 2.236b

50 ± 3.5c

15.10 ± 0.5099b

55 ± 3.5c

< 0.0001

Number of enters in closed arms

5.3 ± 0.7a

2 ± 0.3bc

2.9 ± 0.3c

1.6 ± 0.18c

4.6 ± 0.4ab

< 0.0001

Time spent in closed arm (min)

213 ± 18.07a

280 ± 3.5b

281 ± 3.6b

284.3 ± 2.4b

248.3 ± 1.8ab

< 0.0001