Fig. 5

The representative gene expression cytokines using real-time PCR in the cutaneous samples of mice subjected to Imiq. Topical Roc and CsA reduced significantly the Imiq-induced cutaneous expression of IL-17, IL-23, and TNF-α. The data are expressed as mean ± SEM of three mice per group. ^# P < 0.05, ^## P < 0.01, and ^### P < 0.001 were compared to the Imiq group