Table 1 Histological score of skin burn of control and treated group at different stages stained with H&E., and Crossman’s trichrome graded according to severity into severe (+++), moderate (++), mild (+) and absent (−)
Groups | ||||||
|---|---|---|---|---|---|---|
Lesions | Control | Treated | ||||
| Â | 3rd d | 7th d | 14th d | 3rd d | 7th d | 14th d |
Haematoxylin and eosin | ||||||
 Fibrous tissues formation | – | + | ++ | – | + | +++ |
 Cell mitosis | – | + | ++ | + | ++ | +++ |
 Tissues granulation | – | + | ++ | + | ++ | ++ |
 Re-epithelization | – | + | ++ | + | + | ++ |
 Angiogenesis | – | + | ++ | – | + | +++ |
 Fibroblast | – | + | + | + | + | ++ |
 Neovascularization | – | + | ++ | + | ++ | ++ |
 Ulcerative necrosis with cell debris | +++ | ++ | + | ++ | + | – |
 Inflammatory edema | +++ | +++ | + | +++ | + | – |
 Inflammatory cells infiltration | ++ | ++ | + | ++ | + | – |
Crossman’s trichrome | ||||||
 Extracellular matrix | – | + | ++ | – | + | +++ |
 Fibroblast | – | + | ++ | – | ++ | +++ |
 Collagen fibers | – | + | ++ | + | ++ | +++ |
 Blue-green stained coloration of dense collagen fibers | – | + | ++ | – | ++ | +++ |