Fig. 9

Comparative growth curves representing the drugs augmenting efficacy of punicalagin against E. coli, (A) Time kill curves of E. coli for ceftriaxone with and without punicalagin. Blue: Growth control, no ceftriaxone/punicalagin; Red: punicalagin (30 μg/mL); Grey: Sub-inhibitory concentration of ceftriaxone (60 μg/mL); Yellow: sub-inhibitory concentration of ceftriaxone (60 μg/mL) with sub-inhibitory concentration of punicalagin (30 μg/mL), (B) Time kill curves of E. coli for aztreonam with and without punicalagin. Blue: Growth control, no aztreonam/punicalagin; Red: punicalagin (15 μg/mL); Grey: Sub-inhibitory concentration of aztreonam (15 μg/mL); yellow: Sub-inhibitory concentration of aztreonam (15 μg/mL) with a sub-inhibitory concentration of punicalagin (100 μg/mL)