Table 1 Symptoms and clinical manifestations of DPN
Small-fiber neuropathy | Large-fiber neuropathy | |
|---|---|---|
Function | Nociception and protective sensation | Pressure and balance |
Symptoms | Pain Burning Electric shocks Stabbing | Numbness Tingling Poor balance |
Clinical tests | Pinprick Temperature sensation | Ankle reflexes Vibration perception 10 g monofilament Proprioception |
Findings | Reduced or absent thermal discrimination Reduced or absent Pinprick sensation | Reduced or absent ankle reflexes Reduced or absent vibration perception Reduced or absent 10 g monofilament sensation Reduced or absent proprioception |