Fig. 5

JPYSF suppresses inflammation in cisplatin-induced AKI mice. (a) Representative WB images of pro-inflammatory and anti-inflammatory cytokines, such as TNF-α, IL-6, MCP-1, and IL-10 in the kidneys. (b) – (e) Densitometric analyses of TNF-α, IL-6, MCP-1, and IL-10 proteins expression normalized to GAPDH content (n = 3). (f) Representative IHC images of LY6G protein in renal tissues (n = 3). Scale bar = 20 μm. (g) Quantitative analysis of IHC for the LY6G protein expression. AOD = IOD / area. Data presented are means ± SEM. ∗P < 0.5, ∗∗P < 0.01, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001 vs. the control group; #P < 0.05, ##P < 0.01, ###P < 0.001, ####P < 0.0001 vs. the cisplatin group