Fig. 5
Dialium guineense root extract (DGR) significantly inhibited the migration of MCF-7 cells after 24, 48 and 72 h. (A) Cell migration was calculated and expressed as the percentage of wound area covered by the cells to the initial cell-free wound area after treatment with either solvent control (0.1% DMSO) or DGR at concentrations of 0.5 x GI50 and 1 x GI50. The assay was repeated at least three different times. Bar and error bars represent mean ± SD. ****p < 0.0001 vs control. (B) The representative images of the migratory cells were taken under an inverted microscope at 10X objective