Skip to main content

Table 8 Comet assay of genomic DNA of human lymphocytes exposed to chloroformic extract of Achillea millefolium L. for 24 h

From: HPLC analysis, genotoxic and antioxidant potential of Achillea millefolium L. and Chaerophyllum villosum Wall ex. Dc

 

Negative Control (Only Lymphocytes)

Positive Control (Lymphocytes + H2O2)

50 mg/100 ml

75mg100ml

100 mg/100 ml

Class 0

92.7 ± 2.5

6.7 ± 2.8

42.7 ± 6.8

71.6 ± 7.6

84.0 ± 6.0

Class 1

3.3 ± 1.5

20.6 ± 9.0

21.7 ± 10.4

10.0 ± 5.0

10.0 ± 2.0

Class 2

1.3 ± 1.2

17.6 ± 7.5

15.0 ± 5.0

5.0 ± 5.0

3.0 ± 1.0

Class 3

2.3 ± 2.5

24.0 ± 5.3

11.7 ± 2.8

6.7 ± 2.8

1.3 ± 1.2

Class 4

0.3 ± 0.6

34.3 ± 4.0

7.3 ± 4.0

6.7 ± 2.8

1.3 ± 2.3

TCS

13.3 ± 8.5

265.3 ± 20.4

116.0 ± 5.3*

66.7 ± 18.9**

59.6 ± 58.5***

  1. Values are expressed as mean ± standard deviation (S.D). Difference significant relative to positive control at *P < 0.002, **P < 0.0001, ***P < 0.0001 (One-way ANOVA, Tukey Test)
  2. TCS Total comet score