Skip to main content

Table 7 Comet assay of genomic DNA of human lymphocytes exposed to chloroformic extract Chaerophyllum villosum Wall. ex DC. for 3 h

From: HPLC analysis, genotoxic and antioxidant potential of Achillea millefolium L. and Chaerophyllum villosum Wall ex. Dc

Class

Negative Control (Only Lymphocytes)

Positive Control (Lymphocytes + H2O2)

50 mg/100 ml

75 mg/100 ml

100 mg/100 ml

Class 0

90.0 ± 5.0

15.0 ± 5.0

54.7 ± 2.5

75.0 ± 4.0

81.0 ± 2.6

Class 1

4.0 ± 1.7

43.3 ± 11.5

25.3 ± 4.9

13.3 ± 1.1

11.0 ± 1.7

Class 2

3.3 ± 1.5

20.0 ± 13.2

12.0 ± 2.6

7.7 ± 4.0

4.7 ± 0.6

Class 3

1.6 ± 1.1

16.7 ± 7.6

4.3 ± 1.1

2.7 ± 1.2

2.0 ± 0.0

Class 4

1.0 ± 1.0

8.3 ± 2.8

2.3 ± 1.5

1.3 ± 0.6

1.3 ± 0.6

TCS

19.7 ± 11.6

161.7 ± 48.5

71.7 ± 9.5*

42.0 ± 8.7**

31.7 ± 4.7***

  1. Values are expressed as mean ± standard deviation (S.D). Difference significant relative to positive control at *P < 0.01, **P < 0.002, ***P < 0.001 (One-way ANOVA, Tukey Test)
  2. TCS Total comet score