Skip to main content

Table 6 Comet assay of genomic DNA of human lymphocytes exposed to chloroformic extract of Achillea millefolium L. for 3 h

From: HPLC analysis, genotoxic and antioxidant potential of Achillea millefolium L. and Chaerophyllum villosum Wall ex. Dc

 

Negative Control (Only Lymphocytes)

Positive Control (Lymphocytes + H2O2)

50 mg/100 ml

75mg100ml

100 mg/100 ml

Class 0

90.0 ± 5.0

8.3 ± 5.7

48.3 ± 7.6

60.0 ± 13.2

68.3 ± 16.1

Class 1

6.0 ± 3.6

21.7 ± 10.4

25.0 ± 8.7

19.0 ± 9.6

13.3 ± 7.6

Class 2

3.0 ± 2.0

21.7 ± 7.6

13.3 ± 2.9

14.3 ± 6.0

10.0 ± 5.0

Class 3

0.3 ± 0.6

18.3 ± 7.6

9.3 ± 6.0

6.0 ± 3.6

5.7 ± 3.7

Class 4

0.7 ± 1.2

26.7 ± 12.6

4.0 ± 1.7

4.0 ± 1.7

2.7 ± 2.1

TCS

14.7 ± 8.4

226.7 ± 41.6

95.7 ± 19.0*

81.7 ± 16.6**

58.7 ± 35.8***

  1. Values are expressed as mean ± standard deviation (S.D). Difference significant relative to positive control at *P < 0.003, **P < 0.002, ***P < 0.001 (One-way ANOVA, Tukey Test)
  2. TCS Total comet score