Table 4 Comet assay of genomic DNA of human lymphocytes exposed to methanolic extract of Achillea millefolium L. for 24 h
Negative Control (Only Lymphocytes) | Positive Control (Lymphocytes + H2O2) | 50 mg/100 ml | 75mg100ml | 100 mg/100 ml | |
|---|---|---|---|---|---|
Class 0 | 85.0 ± 5.0 | 12.3 ± 2.5 | 47.7 ± 2.5 | 63.7 ± 3.2 | 76.0 ± 5.2 |
Class 1 | 4.7 ± 0.6 | 25.0 ± 5.0 | 28.3 ± 2.8 | 20.0 ± 2.0 | 11.0 ± 3.6 |
Class 2 | 4.3 ± 1.2 | 31.7 ± 7.7 | 12.3 ± 2.5 | 10.3 ± 2.5 | 6.7 ± 2.1 |
Class 3 | 3.0 ± 2.0 | 20.0 ± 10.0 | 7.7 ± 2.5 | 3.7 ± 1.1 | 3.0 ± 1.0 |
Class 4 | 3.0 ± 2.0 | 11.0 ± 8.5 | 5.7 ± 1.1 | 2.3 ± 0.6 | 1.7 ± 0.6 |
TCS | 32.7 ± 18.6 | 192.3 ± 16.6 | 98.7 ± 12.7* | 61.0 ± 3.6* | 39.0 ± 3.6* |