Table 3 Comet assay of genomic DNA of human lymphocytes exposed to methanolic extract of Chaerophyllum villosum Wall. ex DC. for 3 h
Class | Negative Control (Only Lymphocytes) | Positive Control (Lymphocytes + H2O2) | 50 mg/100 ml | 75 mg/100 ml | 100 mg/100 ml |
|---|---|---|---|---|---|
Class 0 | 85.0 ± 5.0 | 12.3 ± 2.5 | 51.3 ± 1.5 | 69.0 ± 1.0 | 76.7 ± 4.0 |
Class 1 | 4.7 ± 0.6 | 25.0 ± 5.0 | 33.3 ± 1.5 | 21.7 ± 2.1 | 13.7 ± 4.6 |
Class 2 | 4.3 ± 1.2 | 31.7 ± 7.6 | 10.3 ± 2.1 | 6.0 ± 1.0 | 6.7 ± 2.1 |
Class 3 | 3.0 ± 2.0 | 20.0 ± 10.0 | 3.0 ± 1.0 | 2.0 ± 0.0 | 1.7 ± 0.6 |
Class 4 | 3.0 ± 2.0 | 11.0 ± 8.5 | 2.0 ± 1.0 | 1.3 ± 0.6 | 1.7 ± 0.6 |
TCS | 34.3 ± 16.0 | 192.3 ± 16.6 | 69.3 ± 5.8* | 45.0 ± 1.7* | 38.7 ± 4.0* |