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Table 4 Effect of the ethanolic bark extract (EBE) and its successive fractions (1 & 2%) of Thespesia populnea (L.) on wound area contraction in circular excision wound model (n = 10)

From: The study of wound healing activity of Thespesia populnea L. bark, an approach for accelerating healing through nanoparticles and isolation of main active constituents

Groups

Dose (%)

Wound contraction (%)

Day 2

Day 5

Day 7

Day 11

Day 14

G(1)

Normal Control

–

–

–

–

–

–

G(2)

Positive control (untreated)

–

7.31C

14.8 g

48.6C

62.1 C

71.92d

G(3)

Vehicle hydrogel base

–

9.13 b

27.54 d

36.60d

69.24 b

74.8C

G(4)

EBE

1

8.56 bC

21.60 f

54.20c

82.98a

90.10a

G(5)

Pet-B

1

7.22 c

30.13 d

57.96 c

83.73 a

94.55 b

G(6)

Met-B

1

9.11b

31.48 d

53.80 c

81.58 b

87.18 b

G(7)

Etac-B

1

8.54 bc

24.70 de

60.40 b

82.14 b

91.43 a

G(8)

But-B

1

9.76b

16.10 g

37.71 d

53.97 d

72.94 d

G(9)

EBE

2

15.40a

25.94 de

65.60a

85.90a

93.30b

G(10)

Pet-B

2

9.58 b

35.42c

62.05 ab

83.70a

95.10 b

G(11)

Met-B

2

9.65 b

39.30 b

61.5 b

79.23a

87.45a

G(12)

Etac-B

2

9.78 b

44.30a

63.77ab

84.87 a

93.10b

G(13)

But-B

2

10.95 b

24.73e

39.7 d

54.84 d

73.24C

  1. Values are expressed as mean, values with different superscript letters (a-g) in the same column at the same interval differ significantly (P < 0.05), Normal control: healthy group, Positive control: untreated group, Vehicle: hydrogel base
  2. Pet-B petroleum ether, Met-B methylene chloride, Etac-B ethyl acetate, But-B butanol fractions