From: Effects of fish oil supplement on psoriasis: a meta-analysis of randomized controlled trials
Study ID | Intervention | Adverse events |
---|---|---|
Bjørneboe 1988 [13] | Fish oil | Routine lab: none of the parameters changed significantly during the trial (CBC, ESR, creatinine, albumin, ALT, GGT, bleeding time, triglyceride, cholesterol). |
Danno 1998 [14] | Fish oil + Etretinate | Cheilitis, dry mouth, dry eyes, desquamation of palms, folliculitis, gastric symptoms, and increased liver enzymes. All were mild or tolerable. No significant difference in the incidence between intervention and control groups. |
Grimminger 1993 [15] | Fish oil (intravenous) | No obvious side effect except for rare irritations at the site of peripheral intravenous route; routine lab: not change substantially (ESR, CRP, cholesterol, triglyceride, BUN, ALT, GGT, amylase, lipase, coagulation variables). |
Gupta 1989 [17] | Fish oil + UVB phototherapy | No side effect was reported in either group. |
Gupta 1990 [16] | Fish oil + betamethasone diproprionate cream | An occasional fishy taste upon eructation in one patient on fish oil and one on olive oil therapy; transient diarrhea at beginning of therapy in 2 patients on fish oil |
Kristensen 2018 [18] | Fish oil | Mild gastrointestinal adverse effects (9 in intervention group and 6 in control group) |
Mayser 1998 [20] | Fish oil (intravenous) + 3% salicyclic acid | Most frequently reported in intervention group: superficial thrombophlebitis; most frequently reported in control group: superficial thrombophlebitis, pruritus, hypertriglyceridemia, and fever; no severe AEs; routine lab: not substantially change (AST, ALT, Alk-P, creatinine, blood glucose, CBC/DC, total cholesterol, triglyceride) |
Strong 1993 [23] | Fish oil + evening primrose oil | Blood test: remained unchanged throughout the trial (CBC, urea, creatinine, total lipids, HDL and LDL, cholesterol, triglyceride, electrolytes) |
Veale 1994 [24] | Fish oil + evening primrose oil | No significant differences in lab indices including ESR, CRP, hemoglobin, urea, electrolytes, liver enzymes |