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Table 4 Platelet aggregation (%) at different time points

From: Randomized, double-blind, placebo-controlled phase I dose escalation study of Dan Qi Tong Mai tablet in healthy volunteers

Treatment

Cohort

Dose, mg twice daily

Baseline

Day 8

Day 15

Placebo

–

–

61.50 (24.34)

52.67 (23.84)

68.17 (13.82)

Active ingredients

9

360

56.17 (31.56)

68.83 (13.24)

55.00 (15.19)

Active ingredients

10

720

63.50 (14.17)

42.83 (13.91)

58.00 (17.78)

Active ingredients

11

2160

77.00 (7.24)

67.00 (16.78)

72.83 (12.73)

Repeated-measures analysis of variance

Group

F

2.83

  

P value

0.06

  

Time

F

0.97

  

P value

0.36

  

Group*Time

F

1.29

  

P value

0.3

  
  1. Values are mean (SD), unless otherwise noted
  2. *Denote the interaction