Fig. 5

QKL inhibited NLRP3 inflammasome activation post-stroke. (A) Western blot analysis of NLRP3, ASC, pro-caspase 1, cleaved-caspase 1, pro-IL-1β, cleaved-IL-1β and GAPDH. (B-E) Quantitative analysis of NLRP3, ASC, Cl-caspase 1 and cl-IL-1β expression. (F-I) Quantitative polymerase chain reaction (QPCR) analysis of NLRP3, ASC, caspase 1 and IL-1β mRNA. Data points indicate means ± SEM. Vs Sham group, # < 0.05, ## < 0.01, ### < 0.001, Vs MCAO group, * p < 0.05, ** p < 0.01. At least three independent experiments were performed for each group