Time | 24 h. | 14 days | Reference range | ||||
---|---|---|---|---|---|---|---|
Treatment | AE | FF | 1X PBS | AE | FF | 1X PBS | (Midrange) |
BIOCHEMICAL PARAMETERS | |||||||
Glucose (mg/dL) | 118.7 ± 13.8 | 113.7 ± 17.5 | 138.7 ± 17.9 | 130.2 ± 6.9 | 127.7 ± 15.4 | 141.5 ± 10.4 | 63–176 (89) |
Triglycerides (mg/dL) | 70.13 ± 11.3 | 74.6 ± 7.4 | 81.4 ± 8.6 | 121.8 ± 17.2 | 112.75 ± 19.8 | 98.5 ± 7.3 | 55–115 (85) |
Cholesterol (mg/dL) | 76.3 ± 8.5 | 77.5 ± 14.4 | 75 ± 8.2 | 61 ± 12.7 | 55 ± 5.8 | 65 ± 2.8 | 26–82 (64) |
Protein (g/dL) | 5.4 ± 0.5 | 5.5 ± 0.6 | 5.4 ± 0.25 | 5.7 ± 0.63 | 5.2 ± 0.5 | 5.8 ± 0.82 | 4–8.6 (6.2) |
AST (TGO) (U/L) | 205 ± 45.3 * | 152.5 ± 8.7 | 127.5 ± 19.4 | 132 ± 19.7 | 165 ± 45.5 | 161.8 ± 47.5 | 55–251 (139) |
ALT (TGP) (U/L) | 55.9 ± 8.8 | 78.7 ± 0.3 * | 52.9 ± 6.2 | 64.4 ± 1.4 | 74.7 ± 16.1 | 70.7 ± 5.8 | 17–77 (47) |
LDH (U/L) | 1234 ± 221 | 954 ± 281 | 1330 ± 274 | 1122 ± 201 | 980 ± 286 | 997.3 ± 70.3 | 149–215 (182) |
Creatinine (mg/dL) | 0.62 ± 0.2 | 0.5 ± 0.01 | 0.5 ± 0.01 | 0.5 ± 0.01 | 0.5 ± 0.01 | 0.46 ± 0.09 | 0.2–0.9 (0.5) |
Urea (mg/dL) | 60 ± 5.8 | 56.2 ± 4.8 | 53.7 ± 6.3 | 65 ± 4.1 | 57.5 ± 6.5 | 56.7 ± 7.2 | 46.9–73 (60.1) |
HEMATOLOGICAL PARAMETERS | |||||||
Hemoglobin (g/dL) | 15.16 ± 1.09 | 13.5 ± 0.36 | 14.76 ± 0.90 | 16 ± 1.05 | 13.23 ± 1.8 | 14.13 ± 0.20 | 10–17 (13.1) |
Hematocrit (%) | 47.2 ± 4.07 | 39.33 ± 3.40 | 43.93 ± 2.83 | 49.5 ± 3.99 | 38.8 ± 5.63 | 43.7 ± 0.55 | 39–49 (40.4) |
Erythrocytes (X106/mm3) | 9.69 ± 1.16 | 7.34 ± 0.95 | 9.27 ± 0.97 | 9.92 ± 0.85 | 7.91 ± 1.13 | 8.84 ± 0.43 | 8.3 |
MCHC (%) | 32.06 ± 0.66 | 36.36 ± 4.56 | 33.63 ± 1.04 | 32.3 ± 0.52 | 36.26 ± 2.57 | 32.3 ± 0.72 | 32.3 |
MCH (pg) | 15.66 ± 0.8 | 14.63 ± 3.68 | 15.96 ± 0.96 | 16.1 ± 0.34 | 14.3 ± 2.4 | 15.96 ± 0.86 | 15.9 |
MCV (μL) | 48.9 ± 1.6 | 47.26 ± 11.49 | 47.5 ± 1.83 | 49.9 ± 0.3 | 48.9 ± 1.95 | 49.5 ± 1.83 | 49.1 |
Leukocytes (× 100/mm3) | 5000 ± 953.9 | 4233.3 ± 1404.7 | 5666.66 ± 808.29 | 4466.66 ± 929.15 | 4666.6 ± 1242.3 | 5033.33 ± 1227.8 | 5–12 (6.33) |
RDW-CV | 15 ± 1.17 | 18.7 ± 1.56 | 17.96 ± 1.11 | 13.73 ± 0.57 * | 16.33 ± 0.97 | 16.16 ± 1.20 | |
RDW-SD | 24.26 ± 3.18 * | 32.63 ± 18.9 | 33.2 ± 5.32 | 22.8 ± 0.51* | 26.13 ± 1.5 | 25.73 ± 1.38 | |
Platelets (/μL) | 437,333 ± 94,214 | 558,666.6 ± 230,048.5 | 627,000 ± 95,859.2 | 368,000 ± 46,130 | 425,333.3 ± 325,423 | 572,666 ± 158,190 | 116 × 103 |
MPV (fL) | 7.6 ± 0.2 | 7.5 ± 2.4 | 8.16 ± 0.87 | 7.56 ± 0.15 | 9.43 ± 0.49 * | 7.6 ± 0.3 | |
PDW (%) | 14 ± 0.1 | 14.6 ± 4.5 | 14.96 ± 2.32 | 14.06 ± 0.15 | 13.03 ± 2.8 | 14 ± 0.26 | |
PCT (%) | 0.33 ± 0.07 * | 0.27 ± 0.05 * | 0.51 ± 0.12 | 0.277 ± 0.03 * | 0.585 ± 0.12 | 0.432 ± 0.10 | |
Lymphocytes (%) | 67.33 ± 10.06 * | 74 ± 7.21 | 82 ± 2 | 65 ± 13.4 | 63.3 ± 4.16 | 68 ± 20.7 | 35–90 |
Monocytes (%) | 1.33 ± 1.15 | 0 | 0.33 ± 0.57 | 0.33 ± 0.57 | 0 | 0 | 0–3 |
Eosinophils (%) | 2 | 0 | 0 | 0 | 0 | 0 | 0–7 |
Basophils (%) | 0 | 0 | 0 | 0 | 0 | 0 | 0–1 |
Segmented neutrophils (%) | 38 ± 9.16 * | 25.3 ± 7.5 | 17.66 ± 2.08 | 34.66 ± 13.61 | 16.66 ± 4.16 | 24.66 ± 27.30 | 10–40 |
Neutrophils band (%) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immature shape (%) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |