In vitro anti-nephrotoxic potential of Ammi visnaga, Petroselinum crispum, Hordeum vulgare, and Cymbopogon schoenanthus seed or leaf extracts by suppressing the necrotic mediators, oxidative stress and inflammation

Table 2 Effect of the studied plant extracts and Ketosteril (Ks) on the viability of the untreated Vero cells and their effective doses (ED₁₀₀) that produced 100% therapeutic response from the carbon tetrachloride (CCl₄)-induced nephrotoxicity

	Ammi visnaga extract (AVE)	Petroselinum crispum extract (PCE)	Hordeum vulgare extract (HVE)	Cymbopogon schoenanthus extract (CSE)	Ks
EC₁₀₀ (μg/ml)	999.48 ± 49.05 ^d	2209.87 ± 23.96 ^b	2709.07 ± 18.20 ^a	1371.75 ± 7.65 ^c	450.74 ± 1.31 ^e
IC₅₀ (μg/ml)	6334.53 ± 86.20 ^a	9023.38 ± 46.36 ^b	9024.16 ± 611.32 ^b	11,725.59 ± 13.40 ^c	12,785.56 ± 1.24 ^d
ED₁₀₀ (μg/ml)	83.64 ± 3.06 ^a	140.71 ± 1.78 ^b	174.77 ± 2.06 ^cd	148.10 ± 14.42 ^bc	189.05 ± 5.74 ^d

Results are presented as Mean ± SE (n = 3). Different letters in the same row are significantly different at p < 0.05. EC₁₀₀, safe concentrations of the studied extracts that caused 100% viability for Vero cells; IC₅₀, concentration of the studied extracts that caused 50% viability for Vero cells

ISSN: 2662-7671