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Table 4 Neem cream minimum inhibitory and minimum bactericidal concentrations (MIC & MBC)

From: Inhibitory effects of Azadirachta indica secondary metabolites formulated cosmetics on some infectious pathogens and oxidative stress radicals

Test Pathogens Neem cream Controls
NMC NMLC a NMSBC b NMLSBC c Ciprofloxacin d Water e
MIC mg /mL MBC mg / mL MIC mg/mL MBC mg /mL MIC mg /mL MBC mg /mL MIC mg /mL MBC mg/mL MIC mg/mL MBC mg / mL MIC (500 μL)
L. ivanovii 0.800 ± 0.03 0.800 ± 0.01 VG 0.400 ± 0.02 0.800 ± 0.01 NG 0.400 ± 0.02 0.800 ± 0.01 NG 0.400 ± 0.02 0.400 ± 0.02 NG 0.012 ± 0.001 0.050 ± 0.01 NG VG
S. aureus 0.800 ± 0.02 0.800 ± 0.03 VG 0.800 ± 0.04 0.800 ± 0.02 VG 0.800 ± 0.03 0.800 ± 0.03 NG 0.400 ± 0.03 0.800 ± 0.02 NG 0.050 ± 0.001 0.050 ± 0.04 NG V G
M. smegmatis 0.800 ± 0.01 0.800 ± 0.02 VG 0.400 ± 0.02 0.800 ± 0.03 NG 0.800 ± 0.02 0.800 ± 0.01 NG 0.400 ± 0.04 0.800 ± 0.02 NG 0.05 ± 0.02 0.100 ± 0.02 NG V G
E. coli 180* 0.800 ± 0.03 0.800 ± 0.03 VG 0.800 ± 0.01 0.800 ± 0.02 VG 0.800 ± 0.01 0.800 ± 0.01 VG 0.800 ± 0.02 0.800 ± 0.04 VG 0.050 ± 0.01 0.050 ± 0.02 NG V G
V.paraheam-olyticues * 0.800 ± 0.02 0.800 ± 0.03 VG 0.800 ± 0.01 0.800 ± 0.00 VG 0.800 ± 0.11 0.800 ± 0.03 VG 0.800 ± 0.04 0.800 ± 0.03 VG 0.050 ± 0.01 0.050 ± 0.03 NG VG
E. cloacae 0.800 ± 0. 02 0.800 ± 0.04 NG 0.800 ± 0.12 0.800 ± 0.03 NG 0.400 ± 0. 02 0.800 ± 0.01 NG 0.400 ± 0.02 0.800 ± 0.04 NG 0.012 ± 0.001 0.012 ± 0.00 NG ND
S. uberis 0.800 ± 0.02 0.800 ± 0.01 VG 0.800 ± 0.01 0.800 ± 0.03 VG 0.800 ± 0.03 0.800 ± 0.02 NG 0.400 ± 0.01 0.800 ± 0.04 NG 0.050 ± 0.01 0.050 ± 0.04 NG ND
  1. NMS neem cream without neem EO
  2. a NMLC = neem cream with leaf EO, NMSBC = neem cream with stem-bark neem EO
  3. cNMLSBC = neem soap with leaf EO and stem-bark EO
  4. d amphotericin B = positive control
  5. eWater = negative control, P < 0.05
  6. * confirmed bacterial resistant strains