Skip to main content

Advertisement

Table 1 IC50 values (mg/ml) for cytotoxic activity of different extracts towards MDA-MB-231, HT-29, HepG2 and MCF-7 cells a

From: Potent antitumor property of Allium bakhtiaricum extracts

Cell Line/Time MDA-MB-231 HT-29 HepG2 MCF-7
24 h 48 h 72 h 24 h 48 h 72 h 24 h 48 h 72 h 24 h 48 h 72 h
Extracts
 Total 0.03 ± 1.12 0.02 ± 1.09 0.004 ± 1.07 0.08 ± 1.06 0.03 ± 1.06 0.01 ± 1.06 0.05 ± 1.05 0.05 ± 1.05 0.04 ± 1.05 0.05 ± 1.06 0.04 ± 1.06 0.02 ± 1.07
 Hexane >  0.25 >  0.25 0.02 ± 1.15 >  0.25 >  0.25 0.08 ± 1.10 >  0.25 >  0.25 >  0.25 >  0.25 > 0.25 0.2 ± 1.10
 Chloroform 0.07 ± 1.05 0.03 ± 1.10 0.005 ± 1.12 0.04 ± 1.09 0.03 ± 1.12 0.02 ± 1.11 0.08 ± 1.07 0.06 ± 1.08 0.04 ± 1.08 0.06 ± 1.06 0.03 ± 1.08 0.02 ± 1.09
 Ethyl acetate 0.07 ± 1.06 0.04 ± 1.13 0.006 ± 1.10 0.07 ± 1.09 0.05 ± 1.08 0.02 ± 1.09 0.1 ± 1.08 0.1 ± 1.07 0.07 ± 1.10 0.08 ± 1.06 0.06 ± 1.08 0.03 ± 1.06
 Methanol 0.16 ± 1.03 0.05 ± 1.09 0.01 ± 1.06 0.12 ± 1.06 0.07 ± 1.07 0.04 ± 1.09 0.2 ± 1.07 0.1 ± 1.06 0.07 ± 1.07 0.09 ± 1.05 0.06 ± 1.06 0.05 ± 1.07
  1. aValues were determined from at least three independent experiments each performed in triplicate and expressed as mean ± SE