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Table 3 Effect of 1-(2-(2-(2-(1-aminoethyl)phenyl)diselanyl)phenyl)ethanamine (APDP) on hepatic SOD (superoxide dismutase), CAT (catalase) and Ascorbic Acid of mice

From: Acute oral toxicity and antioxidant studies of an amine-based diselenide

Groups(mg/kg)

SODa

CATb

Ascorbic Acidc

Control

21 ± 4.2

65.7 ± 10.7

70.2 ± 3.2

APDP-10

19 ± 5.3

122.6 ± 50.4

72.1 ± 15.6

APDP-100

23 ± 6.1

57.2 ± 10.3

75.4 ± 7.3

APDP-350

18 ± 5.2

53.0 ± 8.9

76.5 ± 4.0

  1. Data are reported as mean ± S.D. Data are reported as mean ± SD of seven animals per group. (*) Denoted p < 0.05 as compared to all groups (one-way ANOVA/Duncan).
  2. Data are expressed as aU SOD mg-1, bU mg-1 protein, cμg ascorbic acid g-1 tissue