Fig. 2

In vivo plasma concentrations of warfarin versus time curves in rats after a single oral dose of 0.5 mg/kg warfarin, along with warfarin in combination with: (a) five doses of pomegranate peel extract (100 mg/kg) and ellagic acid (40 mg/kg), (b) five doses of guava leaves extract (250 mg/kg) and quercetin (12.75 mg/kg). Each data point represents the mean ± SEM (n = 8). *p < 0.05, **p < 0.01