Conc. (μg/ml) | MCa | NMCb | ||||
---|---|---|---|---|---|---|
MG-63 | IMR-32 | HeLa | A-549 | HepG2 | 293 T | |
Inhibition (% ± SE) | ||||||
31.25 | 32.947 ± 0.809 | 08.141 ± 1.339 | 13.583 ± 0.676 | 15.487 ± 0.366 | 36.338 ± 0.972 | 1.695 ± 0.676 |
62.5 | 34.090 ± 0.024 | 20.261 ± 0.235 | 31.336 ± 0.821 | 27.051 ± 1.012 | 44.376 ± 0.570 | 2.452 ± 0.567 |
125 | 37.926 ± 0.280 | 32.510 ± 0.284 | 34.619 ± 0.911 | 46.275 ± 0.411 | 60.264 ± 0.247 | 5.510 ± 0.440 |
250 | 41.271 ± 0.512 | 50.335 ± 0.598 | 47.664 ± 0.903 | 60.716 ± 0.171 | 67.763 ± 0.027 | 7.206 ± 0.621 |
500 | 51.194 ± 0.537 | 63.810 ± 0.402 | 59.736 ± 0.671 | 68.883 ± 0.230 | 84.514 ± 0.021 | 8.689 ± 0.813 |
1000 | 75.440 ± 0.368 | 71.598 ± 0.257 | 63.992 ± 0.677 | 74.007 ± 0.106 | 95.448 ± 0.011 | 9.658 ± 0.424 |
Regression equation | y = 0.043x + 31.28 | y = 19.19ln(x) - 58.24 | y = 14.43ln(x) - 32.89 | y = 17.82ln(x) - 43.52 | y = 17.45ln(x) - 25.54 | y = 2.482ln(x) - 6.976 |
R2 | 0.995 | 0.991 | 0.970 | 0.964 | 0.991 | 0.971 |
IC50 (μg/ml) | 435.349 | 281.586 | 312.399 | 189.025 | 75.864 | 9.322 × 109 |
Camptothecin (10 μM) | 81.86 | 65.68 | 71.60 | 68.07 | 68.13 | 22.62 |