Fig. 4

Nitrite levels. On 0, 7, and 14 postoperative days, animals were sacrificed and samples of excisional wounds were removed to determine nitrite levels by Griess reaction. Data are mean of three independent experiments and are expressed as mean ± SEM of nitric oxide levels (μM). ###p < 0.001 indicated statistical difference diabetic group compared to normal group; * p < 0.05, ** p < 0.01 and *** p < 0.001 indicated treatments groups with respect to diabetic group. (n = 6 animals/group/time point/experiment, ANOVA-Tukey test)