Table 2 List of differentially expressed proteins in vehicle- and γT3-treated senescent cells
From: Proteomic profiling of senescent human diploid fibroblasts treated with gamma-tocotrienol
Protein ID | Protein name (symbol) |
|---|---|
Upregulated | |
O00487 | 26S proteasome non-ATPase regulatory subunit 14 (PSMD14) |
P08865 | 40S ribosomal protein SA (RPSA) |
Q969Q0 | 60S ribosomal protein L36a-like (RPL36AL) |
P30533 | Alpha-2-macroglobulin receptor-associated protein (LRPAP1) |
P40222 | Alpha-taxilin (TXLNA) |
P07355;A6NMY6 | Annexin A2 (ANXA2); Putative annexin A2-like protein (ANXA2P2) |
P08758 | Annexin A5 (ANXA5) |
Q9NUU7;Q9UMR2 | ATP-dependent RNA helicase DDX19A (DDX19A); ATP-dependent RNA helicase DDX19B (DDX19B) |
Q05682 | Caldesmon (CALD1) |
P17612;P22694 | cAMP-dependent protein kinase catalytic subunit alpha (PRKACA); cAMP-dependent protein kinase catalytic subunit beta (PRKACB) |
P17812 | CTP synthase 1 (CTPS1) |
P54886 | Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) |
Q9NZN3 | EH domain-containing protein 3 (EHD3) |
O94905 | Erlin-2 (ERLIN2) |
O75822 | Eukaryotic translation initiation factor 3 subunit J (EIF3J) |
Q9Y262 | Eukaryotic translation initiation factor 3 subunit L (EIF3L) |
P14324 | Farnesyl pyrophosphate synthase (FDPS) |
P14314 | Glucosidase 2 subunit beta (PRKCSH) |
Q06210 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) |
Q9UBQ7 | Glyoxylate reductase/hydroxypyruvate reductase (GRHPR) |
P0DMV9;P0DMV8 | Heat shock 70 kDa protein 1B (HSPA71B); Heat shock 70 kDa protein 1A (HSPA71A) |
Q14103 | Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) |
O14979 | Heterogeneous nuclear ribonucleoprotein D-like (HNRNDL) |
P31942 | Heterogeneous nuclear ribonucleoprotein H3 (HNRNH3) |
P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) |
Q16850 | Lanosterol 14-alpha demethylase (CYP51A1) |
Q96AG4 | Leucine-rich repeat-containing protein 59 (LRRC59) |
P40926 | Malate dehydrogenase, mitochondrial (MDH2) |
P29966 | Myristoylated alanine-rich C-kinase substrate (MARCKS) |
Q96AY3 | Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) |
P48739 | Phosphatidylinositol transfer protein beta isoform (PITPNB) |
O60568 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (PLOD3) |
Q99623 | Prohibitin-2 (PHB2) |
Q86UE4 | Protein LYRIC (MTDH) |
Q96M27 | Protein PRRC1 (PRRC1) |
Q15436 | Protein transport protein Sec23A (SEC23A) |
P35241 | Radixin (RDX) |
Q9UN86 | Ras GTPase-activating protein-binding protein 2 (G3BP2) |
Q15019 | Septin-2 (SEPT2) |
P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) |
Q9BWM7 | Sideroflexin-3 (SFXN3) |
P08240 | Signal recognition particle receptor subunit alpha (SRPRA) |
O43765 | Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) |
Q9Y5X3 | Sorting nexin-5 (SNX5) |
Q8WZ42 | Titin (TTN) |
P60174 | Triosephosphate isomerase (TPI1) |
P09493 | Tropomyosin alpha-1 chain (TPM1) |
P06753 | Tropomyosin alpha-3 chain (TPM3) |
Q96FW1 | Ubiquitin thioesterase (OTUB1) |
Downregulated | |
Q15435 | Protein phosphatase 1 regulatory subunit 7 (PPP1R7) |
Q59GN2;P62891 | Putative 60S ribosomal protein L39-like 5 (RPL39P5); 60S ribosomal protein L39 (RPL39) |