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Table 5 Effect of E. umbellata fruit methanolic extract/fractions on lipid profile in streptozotocin induced diabetic rats

From: Phytochemical analysis and antidiabetic potential of Elaeagnus umbellata (Thunb.) in streptozotocin-induced diabetic rats: pharmacological and computational approach

S.No Groups Dose (mg/kg) TC (mg/dl) TGs (mg/dl) HDL(mg/dl) LDL(mg/dl)
1 aNormal control 0.3 ml 125 ± 6.10** 123.6 ± 8.5** 37 ± 3.1* 74 ± 5.5**
2 bDiabetic control 0.3 ml 163.3 ± 6.5 165.0 ± 7.9 25.2 ± 2.2 170.4 ± 8.9
3 cGlibenclamide 0.5 138.5 ± 6.3** 125.3 ± 5.5** 40.5 ± 4.5** 89.3 ± 5.5***
4 cMe-Ext 100 140.2 ± 5.3* 145.5 ± 7.7* 33.5 ± 4.3* 145.6 ± 4.2*
5 cMe-Ext 200 131.5 ± 7.5** 138.8 ± 6.5** 36.6 ± 5.5* 93.5 ± 4.6**
6 cChf-Ext 100 145.4 ± 5.5* 143.2 ± 3.2* 34.2 ± 2.5* 125.3 ± 3.5*
7 cChf-Ext 200 135.4 ± 5.7** 133.2 ± 5.1** 37.2 ± 3.5* 95.3 ± 3.5**
8 cEtAC-Ext 100 147.2 ± 5.6* 146.8 ± 4.0* 30.1 ± 4.5* 123.8 ± 6.0*
9 cEtAC-Ext 200 137.2 ± 7.6** 136.8 ± 5.0** 36.1 ± 5.5* 93.8 ± 8.0**
  1. Each value is mean ± SEM of 8 animals. Comparisons were made between anormal control to bdiabetic control using student t-test (*p < 0.05, **p < 0.01) and between bdiabetic control to positive control c(Glibenclamide/extracts) treated groups using one way ANOVA followed by Dunnett’s posthoc multiple comparison test (* p < 0.05,** p < 0.01, ***p < 0.001)