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Table 2 Adverse events of included trials

From: Efficacy and safety of Tripterygium wilfordii hook F for chronic urticaria: a systematic review and meta-analysis

Study Adverse events
(author/year) Intervention Control
Pi 2006 [13] Two menstrual disorders Five drowsiness
Zhang 2007 [14] Eight drowsiness, sleepiness and fatigue, gastrointestinal disorder, menstrual disorders Five drowsiness, dry mouth, dizzy
Bao 2008 [15] Seven drowsiness, sleepiness and fatigue, dry mouth; two gastrointestinal disorder, menstrual disorders Five drowsiness, sleepiness and fatigue, dry mouth
Xu 2009 [16] Five drowsiness, sleepiness and fatigue, dry mouth; one irregular menses, abnormal liver function Four drowsiness, dizzy; two gastrointestinal disorder
Wei 2010 [17] Three drowsiness, sleepiness and fatigue, dry mouth; two gastrointestinal disorder; one headache, dizzy; one menstrual disorders, abnormal liver function Three drowsiness, sleepiness and fatigue, dry mouth; two gastrointestinal disorder; two headaches, dizzy;
Zhong 2011 [18] Four cases including drowsiness, sleepiness and fatigue, gastrointestinal disorder Five cases including drowsiness, sleepiness and fatigue, gastrointestinal disorder
Liu 2011 [19] Two drowsiness; one sleepiness and fatigue; three gastrointestinal disorder; one bloating; two menstrual disorders Two drowsiness; two dry mouth; one dizzy;
Qian 2011 [9] Four gastrointestinal disorder; three dizzy; three insomnias; three palpitation; three alopecia Seven drowsiness; one dizzy; one general malaise
Yu 2011 [20] One gastrointestinal disorder; one dizzy Two headaches, gastrointestinal disorder
Lu 2012 [21] Two drowsiness; one sleepiness and fatigue; two gastrointestinal disorder; one dry mouth One drowsiness; one sleepiness and fatigue; two dry mouth
Zhou 2012 [22] 10 gastrointestinal disorder; three abnormal liver functions No significant side effects.
Fan 2013 [23] Two drowsiness; three sleepiness and fatigue; two dizzy Two drowsiness; two sleepiness and fatigue; two dizzy
Liu 2013 [24] Nine drowsiness; two dry mouth 11 drowsiness; three dry mouth
Zheng 2013 [25] One drowsiness; one sleepiness and fatigue; one gastrointestinal disorder; one headache One dizzy; one gastrointestinal disorder; one dry mouth
Chen 2014 [26] Two drowsiness, sleepiness and fatigue; four gastrointestinal disorder; Four drowsiness, sleepiness and fatigue;
Wang 2014 [27] One drowsiness; one sleepiness and fatigue; one gastrointestinal disorder One drowsiness; one sleepiness and fatigue; two gastrointestinal disorder
Zhou 2014 [28] Two drowsiness, sleepiness and fatigue, dry mouth; one gastrointestinal disorder; one headache, dizzy; one abnormal liver function Two drowsiness, sleepiness and fatigue, dry mouth; one gastrointestinal disorder; one headache, dizzy;
Li 2016 [29] One dizzy Three drowsiness; one sleepiness and fatigue; one dizzy
Liu 2016 [30] Three drowsiness; two gastrointestinal disorder; two dizzy One drowsiness; two gastrointestinal disorder; one dizzy
Chen 2017 [31] One headache, dizzy; one gastrointestinal disorder One drowsiness; two headaches, dizzy; one gastrointestinal disorder
Tao 2017 [32] Three drowsiness, sleepiness and fatigue; five gastrointestinal disorder; Five drowsiness, sleepiness and fatigue;