Treatment group | Spleen index (mean ± SD) | Spleen index reduction | Log CFU in 0.1 g spleen (mean ± SD) | Log reduction |
Non infected | 0.3 ± 0.2 | Control | – |  |
Pretreatment | 1.09 ± 0.4* | ↑0.79 | 5.46 ± 0.15 |  |
Non treatment | 0.96 ± 0.2* | ↑0.66 | 4.5 ± 0.1 | Control |
Doxycycline | 0.15 ± 0.01* | ↓0.15 | 2.05 ± 0.07** | 2.45 |
Combination treatment | 0.19 ± 0.07* | ↓0.11 | 2.1 ± 0.2** | 2.4 |
C.mongolica root extract | 0.32 ± 0.05 | ↑0.02 | 3.03 ± 0.15 | 1.47 |