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Table 1 Effect of extracts of Zanthoxylum armatum and standard drug Glibenclamide on body weight of normal and alloxan monohydrate induced diabetic mice

From: Zanthoxylum armatum DC extracts from fruit, bark and leaf induce hypolipidemic and hypoglycemic effects in mice- in vivo and in vitro study

Groups Body weight in grams
Before treatment After 7 days After 15 days % Variation
Normal 27.67 ± 2.3 30.83 ± 4.3 34.33 ± 6.3 10.77%
Diabetic control 32 ± 1.8 28 ± 3.0 25 ± 3.8** 12.39%
Normal Zf treated 29.67 ± 2.33 31.33 ± 2.50 33.83 ± 2.04** 6.62%
Diabetic Zf treated 31 ± 1.1 25 ± 1.8 26 ± 2.4 12.81%
Normal Zb. Treated 29.67 ± 2.33 31.00 ± 2.09 33.00 ± 2.09** 5.37%
Diabetic Zb treated 30.00 ± 2.82 28.83 ± 3.83 27.27 ± 3.06 4.77%
Normal Zl treated 30.00 ± 1.78 31.00 ± 1.67 32.83 ± 1.83 4.59%
Diabetic Zl treated 29.00 ± 2.75 21.67 ± 2.94 24.50 ± 1.04 14.96%
Diabetic Glibenclamide (10 mg/kg)treated 30 ± 1.8 30.01 ± 1.7 29.3 ± 1.8 13.39%
  1. Data represented as mean ± S.D. values of 6 animals each *p < 0.001, **p < 0.05 (One wayANOVA, Dunnet’s t-test, Graph pad prism software). Normal control was compared with extract treated normal groups. The diabetic control was compared with extract treated diabetic groups and standard