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Table 13 Biochemical parameters of the rats in sub-acute oral toxicity test

From: Acute and sub-acute oral toxicity of Dracaena cinnabari resin methanol extract in rats

Biochemical parameters Groups P value
Sex Control DC 500 mg/kg DC 1000 mg/kg DC 1500 mg/kg
Urea (mmol/L) M 3.76 ± 0.59 3.92 ± 0.34 4.14 ± 0.38 4.18 ± 0.51 0.466
F 3.90 ± 0.74 4.06 ± 0.44 3.97 ± 0.69 4.16 ± 1.24 0.963
Creatinine (umol/L) M 24.20 ± 4.15 24.00 ± 2.55 23.60 ± 6.91 27.20 ± 4.15 0.615
F 28.60 ± 3.05 28.40 ± 2.70 27.40 ± 2.70 28.80 ± 1.92 0.839
Albumin (g/L) M 35.00 ± 2.24 34.60 ± 1.14 36.20 ± 5.26 34.60 ± 1.67 0.817
F 35.00 ± 1.58 34.60 ± 2.40 36.20 ± 2.17 34.00 ± 2.55 0.470
Globulin (g/L) M 20.60 ± 1.14 21.00 ± 1.58 21.20 ± 1.48 21.20 ± 1.30 0.890
F 22.40 ± 1.14 21.80 ± 1.10 22.80 ± 1.30 21.20 ± 1.48 0.245
Total bilirubin (umol/L) M 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00
F 2.00 ± 0.00 2.00 ± 0.00 2.00 ± 0.00 2.00 ± 0.00
Conjugate bilirubin (umol/L) M 1.40 ± 1.14 1.00 ± 0.00 0.40 ± 0.55 1.00 ± 1.22 0.379
F 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00
ALP (U/L) M 216.20 ± 16.99 218.40 ± 12.70 222.40 ± 18.51 236.40 ± 12.74 0.203
F 204.20 ± 14.64 210.80 ± 29.52 209.60 ± 23.70 197.60 ± 16.33 0.769
ALT (U/L) M 29.60 ± 3.29 29.40 ± 1.52 29.60 ± 2.30 32.00 ± 2.83 0.356
F 23.40 ± 3.21 23.60 ± 3.05 25.40 ± 3.36 26.80 ± 1.64 0.243
AST (U/L) M 104.80 ± 6.69 106.00 ± 3.94 105.40 ± 5.55 109.00 ± 4.95 0.623
F 99.60 ± 7.40 103 ± 2.30 103.60 ± 3.44 104.60 ± 2.41 0.320
  1. Values expressed as a mean ± standard deviation, n = 5. Sex (male, M and female, F)
  2. *p-value less than 0.05, (p < 0.05) significant value