Screening of Baccaurea ramiflora (Lour.) extracts for cytotoxic, analgesic, anti-inflammatory, neuropharmacological and antidiarrheal activities

Table 5 Antidiarrheal effects of the methanol extract of the Baccaurea ramiflora pulp and seed on castor oil induced diarrhea in mice

Group	Dose	No. of faces in 4 h	% inhibition of defecation
Negative Control (1% tween 80 in water)	–	23.8 ± 1.6	–
Positive control (loperamide)	3 mg/kg	9.2 ± 1.14^*	61.34
MEBRP	100 mg/kg	12 ± 1.6^*	50
MEBRP	200 mg/kg	9.6 ± 1.1^*	59.7
MEBRS	100 mg/kg	11.6 ± 1^*	51.26
MEBRS	200 mg/kg	8.8 ± 1.1^*	63.03

Values are means ± S.E.M. of five mice (n = 5)
^*p < 0.05 considered as significant compared to control (One-way ANNOVA followed by Dunnet’s test). Control mice received vehicle (1% Tween 80 in water), positive control mice received loperamide 3 mg/kg body weight, MEBRP and MEBRS treated groups were administered with 100 and 200 mg/kg body weight (p.o.), respectively

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