Skip to main content

Advertisement

Table 1 Changes on the histomorphometrical analysis of hind paw skins

From: Combination of Pelargonium sidoides and Coptis chinensis root inhibits nuclear factor kappa B-mediated inflammatory response in vitro and in vivo

Regions Index Groups Dorsum pedis skin Ventrum pedis skin
Thickness (epidermis to dermis; μm) Infiltrated inflammatory cells (cells/mm2 of dermis) Thickness (epidermis to dermis; μm) Infiltrated inflammatory cells (cells/mm2 of dermis)
Normal 554.49 ± 45.78 33.20 ± 6.98 367.00 ± 47.70 38.60 ± 5.81
Carrageenan (CA) 1374.91 ± 133.42a 300.80 ± 48.15a 1103.50 ± 163.77d 1899.20 ± 240.07d
CA + Dexamethasone 705.25 ± 69.63bc 67.60 ± 19.51c 507.85 ± 70.23ef 552.80 ± 111.52df
CA + PS + CR 0.3 (g/kg) 1013.45 ± 89.90ac 197.60 ± 20.72ac 856.48 ± 83.57df 1167.60 ± 213.76df
CA + PS + CR 1.0 (g/kg) 885.66 ± 85.71ac 129.00 ± 41.48ac 605.99 ± 42.23df 808.20 ± 178.40df
  1. Values are expressed as mean ± S.D. of five rat hind paws
  2. ap < 0.01 and bp < 0.05 as compared with normal by LSD test. cp < 0.01 as compared with CA by LSD test
  3. dp < 0.01 and e p < 0.05 as compared with normal by MW test. fp < 0.01 as compared with CA by MW test