MMSE change | |||||
---|---|---|---|---|---|
6 m | 12 m | 18 m | 24 m | ||
Mild (MMSE 21–26) | |||||
CT + H | mean ± SE | 0.03 ± 0.42 | −0.15 ± 0.47 | −1.21 ± 0.40 | −0.06 ± 0.48 |
95% CI | −0.83 to 0.88 | −1.12 to 0.81 | −2.09 to −0.33 | −1.1 to 0.97 | |
N | 36 | 32 | 14 | 15 | |
CT | mean ± SE | −0.16 ± 0.75 | 0.13 ± 0.83 | −2.66 ± 0.77 | −2.66 ± 0.73 |
95% CI | −1.75 to 1.41 | −1.66 to 1.93 | −4.36 to −0.96 | −4.27 to −1.05 | |
N | 18 | 15 | 11 | 12 | |
P value | 0.043 | 0.660 | 0.030 | 0.012 | |
Moderate (MMSE 10–20) | |||||
CT + H | mean ± SE | 1.5 ± 0.63 | 0.46 ± 0.91 | −1.9 ± 0.7 | −2.84 ± 0.61 |
95% CI | 0.21 to 2.78 | −1.49 to 2.42 | −3.49 to −0.3 | −4.19 to −1.49 | |
N | 28 | 15 | 10 | 13 | |
CT | mean ± SE | 1.14 ± 0.68 | −2.38 ± 0.67 | −3.6 ± 0.42 | −5 ± 0.34 |
95% CI | −0.34 to 2.62 | −3.85 to −0.91 | −4.5 to −2.69 | −5.75 to −4.24 | |
N | 14 | 13 | 15 | 14 | |
P value | 0.196 | 0.001 | 0.253 | 0.025 |