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Table 1 MS/MS data and identification of detected ZAs

From: Comparative study on alkaloids and their anti-proliferative activities from three Zanthoxylum species

Peak NO. Rt (min) M+/ [M + H]+ (m/z) MS/MS spectrum Identification
1 4.67 192 192,177,162,148,133 3,4-dihydro-6,7-dimethoxy-isoquinolinea
2 6.11 206 206,190,173,162,145,132 Edulitine
3 7.39 208 208, 176,160,145,117,115 Thalifoline
4 8.83 462 300, 269,237,209,197,175,143, 115, 107 7-methoxy-2-methylhigenamine-4′-glucosideaor7-methyoxy-2-methylhigenamine-6-glucosidea
5 10.92 194 194,177,162,149,145,134,117, 89 Des-N-methyl-thalifolinea
6 11.67 476 476,314, 283,269,268,252,237, 209, 189,174,166,137, 107 Magnocurarine-6-glucosidea
7 12.99 314 314,269,237, 209, 166,137, 107 Magnocurarineb
8 13.01 286 286,269,254,237, 160,143,107 7-methoxylhigenamineb
9 14.09 356 356,338,323,206,188,179,151,149 Hunnemannineb
10 14.41 504 504,459,442,428,414,401,386,357,306,212,207 Unidentified
11 14.61 342 342,297,282,265, 237,222,219,207, 191 Magnoflorineb
12 12.28 300 300, 269,254,237, 160,143,107 7-methoxy-N-methylhigenaminea
13 15.85 434 434,272,255,237,161,143,123,107 2-dihydroxy-3-methoxy-10-methyl-9-acridone-1-glucosideaor1-dihydroxy-3-methoxy-10-methyl-9-acridone-2-glucosidea
14 16.26 328 328,312,234,205,190,178,163,148,135,119,91 Unidentified
15 16.43 344 344,301, 269,239,207, 143,137 (−)-isotembetarineor (−)-xylopinidine
16 17.31 390 390, 330, 285,269,254,241,237, 181 Unidentified
17 17.76 312 312,297,268,252,240,226,192,177,121 Unidentified
18 17.87 330 330,207,192,177, 175,143,137, 115 Reticulineb
19 18.16 290 290,272,242,218,201,188,175,160,132 4′-methoxy-ribalininea
20 18.36 342 342,282,265,250,237,233,222,205,191 Laurifolineb
21 19.56 314 314,269,237, 209, 166,137, 107 Magnocurarineb
22 19.92 358 358,298,283,267,239,221,206,189,174,158,151,137,122,115,105 8-methoxy-isotembetatrinea
23 20.53 356 356,340,289,206,192, 177,163,149 Tetrahydropalmatineb
24 20.58 260 260,242,200,188,176,160,134 Ribalinine
25 20.92 540 540,313,287,272,268,253,249,201,175,163,143,131 Unidentified
26 20.98 356 356,192,177, 151,149 N-methyltetrahydrocolumbamineb
27 21.35 340 340,325,291, 190,161,149,119 2-methoxy-5-dehydro-scoulerinea
28 21.63 352 352,337, 322,319,308,291,280,266 Buegenine
29 21.71 356 356, 311,296,279,264, 248,236, 219,192,177 Menisperineb
30 25.59 354 354,339,322,311,308,293,280,262,252 2-dimethoxy-3-hydroxybeugeninea
31 22.77 512 512,350,335,307,292,264 Unidentified
32 23.07 328 328,283,251,238,208,191,159,143,121 10-demethyl-magnoflorine or avicineb
33 23.31 366 366,350,334, 322,318,294,276 6-methyl-5,6-dihydrofagaridineb
34 24.7 356 356,311,296,280,265,253,237,219, 192,177 Xanthoplanineb
35 25.33 422 422,260,242,224,210, 188 Ribalinine 3′-glucosideb
36 25.6 314 314,269,237, 209, 166,137, 107 Magnocurarineb
37 25.92 452 452,290,272,257,242,240,239,225,218 4′-methoxy-ribalinine-3′-glucosideb
38 26.66 680 680,662, 547,435, 322,227,209,114 Unidentified
39 27.24 368 368,352,338, 324,310,307,292,278 10-hydroxy-2,3,9,12-tetramethoxy-jatrorrhizinea
40 27.11 354 354,338,190,175,149 N-methylcanadine or its isomersb
41 28.18 342 342,282,266,251,235,206,189,174,158, 135,121 Unidentified
42 29.04 370 370,352,320,290,206,188,165,149 α-allocryprotopineb
43 30.05 384 384,368,352,337,335,320,306,292 6,10-dihydroxyl-3-demethyldihydrobenzophenanthridiniumb
44 30.33 338 338,322,308,294,280,279,265 Jatrorrhizineb
45 31.44 370 370, 308,206, 190,173,162,145 N-methyltetrahydropalmatine
46 32.69 292 292,274,256,226,202,188,172,144, 117 Unidentified
47 33.13 354 354,338,190,175,149 N-methylcanadine or its isomersb
48 34.03 350 335,334,320,307,292,277,264,236 Fagaronine
49 34.75 354 354,338,322,310,294, 190 Unidentified
50 35.89 246 246,231,216,202,188,184,156 Haplopineb
51 36.63 334 334,319,304,291,276,262 8-O-demethylchelerythrineb
52 37.38 352 336,322,320,308, 292, 278,264 Palmatineb
53 38.88 336 336,320,306,304,292,278,262 Berberineb
54 38.96 332 332,317,304,287,274,261,246,215 Sanguinarineb
55 40.38 490 490,288,272,246,240 Unidentified
56 41.66 498 498,336,321,305,293,264,250 8-O-demethyl-dihydrochelerythrine −9-glucosidea
57 42.3 468 468,288,270,260,225,242,218,190, 164 Unidentified
58 44.69 380 380,364,349, 320,306,292,278,249 8-methoxy-dihydronitidinea or 8-methoxy-dihydrochelerythrinea
59 44.71 322 322,304,286,271,256,232,217, 201,189,174,159,145 Unidentified
60 45.22 348 348,332,318,304,290 Nitidineb
61 45.22 364 364,348,334,332,320,304,290,246 Dihydrochelirubineb
62 48.2 348 348,332,318,304,290 Chelerythrineb
63 52.84 364 364,348,334, 316,306,289,276 Oxychelerythrineb
64 55.71 382 382,364, 320,306,292,277,265, 201 6-methoxy-dihydronorchelerythrineN-oxideaor6-methoxy-dihydrorhoifoline B N-oxidea
65 56.32 322 322,307,292,279,264 Berberrubineb
66 59.18 336 336,321,305,293,278,264,250 8-O-demethyl-dihydrochelerythrinea
67 61.75 272 272,257,242,215,196,174,164,149,135 1,2-dihydroxy-3-methoxy-10-methyl-9-acridone
68 62.26 320 320,305,277,248 9,10-didemethylchelerythrine
69 63.48 334 334,318,304,290,276 Dihydrosanguinarineb
70 65.6 380 380,362,334,332,316,304,289,275 6-hydroxy-10-methylsanguinarineb
  1. afirstly reported in the genus zanthoxylum
  2. bidentified by comparing with literatures