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Table 8 Clinical chemistry data for male rats treated with JDHY granules for 13 weeks

From: Subchronic toxicity of herbal compound “Jiedu Huayu” granules in rats

Dose (g/kg/d) 0 80 100 130
Males
 AST(U/L) 217.31 ± 45.65 220.68 ± 66.49 219.30 ± 86.66 196.71 ± 77.69
 ALT(U/L) 61.57 ± 9.09a 61.62 ± 10.59 56.86 ± 10.71 58.01 ± 12.24
 ALP(U/L) 221.68 ± 88.98 239.23 ± 64.49 242.42 ± 81.93 266.23 ± 82.01
 TP(g/L) 85.04 ± 4.67 82.7 ± 06.51 80.61 ± 6.84 86.03 ± 5.78
 ALB(g/L) 42.04 ± 4.63 41.80 ± 4.78 40.84 ± 5.50 38.76 ± 5.31
 TBIL(umol/L) 7.98 ± 2.34 8.30 ± 2.54 7.91 ± 2.30 7.86 ± 3.32
 CHOL(mmol/L) 1.42 ± 0.45 1.64 ± 0.49 1.44 ± 0.46 1.53 ± 0.33
 TG(mmol/L) 0.33 ± 0.11 0.35 ± 0.11 0.36 ± 0.08 0.38 ± 0.08
 GLU(mmol/L) 7.06 ± 0.97 7.43 ± 0.74 7.33 ± 0.71 7.65 ± 0.91
 BUN(mmol/L) 6.80 ± 1.11 6.78 ± 1.64 6.46 ± 1.41 6.47 ± 1.61
 Cr(umol/L) 97.32 ± 15.24 97.65 ± 15.57 99.23 ± 15.67 98.54 ± 13.81
 CK(U/L) 155.05 ± 25.48 147.16 ± 23.52 153.79 ± 26.00 150.48 ± 24.85
 Na+(mmol/L) 150.29 ± 17.72 143.53 ± 15.43 141.36 ± 18.28 145.52 ± 21.69
 K+(mmol/L) 4.59 ± 0.93 5.07 ± 1.31 4.96 ± 1.07 5.01 ± 0.84
 Cl(mmol/) 110.30 ± 6.30 105.50 ± 7.89 105.40 ± 6.93 108.00 ± 7.07
  1. All samples were collected from five rats in each group
  2. aData are given as mean ± SD
  3. ANOVA analysis indicated no statistical significance P > 0.05